NeoStrata Review - The Dermatology Review

NeoStrata Review

Skin Care Reviews


Brand background

NeoStrata is a skincare brand that offers dermatologist grade anti-aging skin care products. The name NeoStrata translates to “new layers”, which describes the brand’s skincare philosophy: that visible results come from renewing layers of the skin. This philosophy began in 1974 when Neostrata founders discovered the profound benefits of alpha hydroxy acids (AHAs) on skin. Today, Neostrata is sold by doctors in 85 countries and has more than 100 publications and patents. In this Neostrata review, we’ll discuss key products, key formulation details, NeoStrata reviews from real customers, and an alternative for your to consider. 

Key products

As mentioned above, NeoStrata is well known for their use of AHAs. We’ll discuss how AHAs can benefit your skin in the next section, but first we want to introduce a few of NeoStrata’s most popular products: Foaming Glycolic Wash, Intensive Eye Therapy, and Bionic Face Cream. 

NeoStrata Foaming Glycolic Wash is a high strength AHA cleanser designed for experienced glycolic acid users. This cleanser is formulated to exfoliate and cleanse congested pores to prepare the skin for optimal benefits of the regimen that follows.

Looking for a NeoStrata eye cream? Intensive Eye Therapy is a good choice for those who have eyelid sagging, crow’s feet, and under eye wrinkles. This anti-aging cream uses multiple mechanisms to build and plump the appearance of slack eye skin.

NeoStrata Bionic Face Cream is said to provide intense hydration, as well as help to soothe and revitalize the look of stressed skin. This rich, soothing emollient is fragrance free and specifically designed for dry, sensitive skin.

Key formulation

Many of NeoStrata’s product formulations include alpha hydroxy acids (AHAs), a family of acids that have the unique ability to slough away surface skin cells to reveal new healthy ones for softer, smoother, less visibly lined skin. AHAs can be naturally derived from fruit and milk sugars or synthetically produced. For example, glycolic acid can be isolated from natural sources like sugarcane, sugar beets, pineapple, cantaloupe, and unripe grapes. 

Glycolic acid is the AHA used in the NeoStrata Foaming Glycolic Wash. Glycolic acid is unique because it has the smallest molecular size out of all the AHAs. So why should you care about molecular size? Molecular size matters because the smaller a molecule, the more easily it gets into the skin. Thus, glycolic acid penetrates the skin better and faster than all of the others. This is why glycolic acid is considered to be the strongest AHA. Other AHAs that are used in NeoStrata skin care products include lactic acid, mandelic acid, tartaric acid, malic acid, and citric acid. 

NeoStrata also uses polyhydroxy acids (PHAs) and Bionic polyhydroxy acids. PHAs are second generation hydroxy acids that are similar to AHAs but provide high-strength anti aging benefits without irritation. Therefore, PHAs are an ideal choice for sensitive skin types. Bionic PHAs are third generation hydroxy acids that are non-irritating, but they are also strong chelators and humectants. Bionic PHAs are ideal for very dehydrated, dry skin types.

Both PHAs and Bionic PHAs are included in the NeoStrata Bionic Face Cream. The first is gluconolactone, which provides anti-aging, antioxidant, and gentle exfoliating benefits without sun sensitivity. In addition, gluconolactone strengthens the skin’s moisture barrier, thereby leaving it more resilient. Bionic Face Cream also includes lactobionic acid, a Bionic PHA. Derived from natural sugars, this patented ingredient helps to reduce the appearance of lines and wrinkles, discoloration, enlarged pores, and roughness through gentle exfoliation. In addition, lactobionic acid is a potent antioxidant that has been shown to target naturally-occurring, skin degrading enzymes to help maintain a youthful look. Lastly, lactobionic acid is a humectant, which means it has the ability to attract moisture to the skin and hold it there to prevent dehydration. 

NeoStrata includes their patented ingredient called Neoglucosamine in Intensive Eye Therapy. Neoglucosamine, a non-acid amino sugar technology, is a building block of skin’s natural filler hyaluronic acid. This ingredient gently exfoliates to reveal fresh new cells, diminishes the appearance of lines and wrinkles, and targets hyperpigmented spots for a more even skin tone. Other beneficial ingredients in this NeoStrata eye cream include caffeine, peptides, and plant stem cells. 

NeoStrata reviews

NeoStrata reviews on the brand’s website are overall very positive, with each of the key products mentioned above receiving an average of at least 4.3 out of 5 stars. 

NeoStrata Foaming Glycolic Wash has an average rating of 4.8 out of 5 stars after 50 customer reviews. Positive reviews for this product say that it is really great for those with oily and acne prone skin. For example, one review says, “I’ve used this product for almost a year and a half and LOVE it!! I have very oily, blemish prone, and uneven toned skin. After I started using this product, I noticed that my face started to glow more, it became less oily, and the blemishes improved!” There aren’t many negative reviews for this product, but the few that are on the website say that it can cause the skin to become dry. 

NeoStrata Intensive Eye Therapy has an average rating of 4.6 out of 5 stars after 163 customer reviews. One positive review for this NeoStrata eye cream says, “I love this product! It visibly improved the texture of my under eyes leaving them look fresh and bright! I would recommend this product to friends and family. It is a bit pricey though.” However, there are quite a few negative reviews that say this eye cream really did not show any visible results. 

NeoStrata Bionic Face Cream has an average rating of 4.3 out of 5 stars after 824 customer reviews. The majority of the positive reviews for this cream were incentivized, meaning the customer received a free sample of the product in exchange for the review. Most of the negative reviews for the Bionic Face Cream have one common theme: it leaves your skin very greasy. For example, one review says, “I really did not like this. It was too thick for my skin and felt like smearing thick vaseline all over my face. It didn’t absorb and I was left with a sticky face even after a full nights sleep.”

What are some alternatives to NeoStrata?

NeoStrata has a reputation for discovery and innovation in skincare, especially with their use of AHAs, PHAs, bionic PHAs, Neoglucosamine, and more. The brand’s most popular product, NeoStrata Foaming Glycolic Wash, can help improve skin texture, pigmentation, tone, and clarity. However, keep in mind that the NeoStrata Foaming Glycolic Wash should only be used by experienced glycolic acid users since this is a high strength formulation. 

If you’re new to using glycolic acid but want to reap all of the benefits of this multi-tasking ingredient, we recommend Formulyst Clarifying AHA Cleanser. This cleanser can be used by all skin types and is formulated with glycolic acid to gently cleanse and exfoliate the skin while removing dirt and makeup. Glycolic acid exfoliates the skin by targeting corneocytes (dead skin cells that make up the top layers of skin) in a process called corneocyte desquamation. By enhancing their breakdown and increasing the separation of skin cells, the rate of cell turnover is increased, leading to smoother, brighter skin. Glycolic acid can also help to refine pores, boost hydration, control excess oil, and even stimulate new collagen production.




The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Many of the Formulyst’s products harness the power of plant and citrus extracts as well as gold-standard workhorses such as retinol. Read More

Advanced Dermatology

The Advanced Dermatology skin care regimen addresses the most pressing aging concerns. It can be used by men and women in their 20s, 30s, 40s, 50s, 60s and beyond. This award-winning system can help diminish wrinkle appearance, reduce dark spots and hyperpigmentation, fade away redness, even out skin tone and improve the appearance of eye bags and dark circles. Some of the standout products in this line include the Super Youth Serum, Complete Age Defense and Anti-Wrinkle Firming Night Treatment. Read More

Neostrata Foaming Glycolic Wash Review

The Neostrata Foaming Glycolic Wash offers an extremely effective, active cleanser to those who need a little extra purifying and exfoliating in their everyday routine. This self-foaming, water based cleanser has been designed to deeply purify the skin without stripping it completely of its natural oils. Harsh surfactants can often strip the skin, leaving you feeling tight, dry and uncomfortable. But the Neostrata Foaming Glycolic Wash proves that you can have a foaming and exfoliating cleanser without damaging or disrupting your skin’s moisture barrier. In fact, this cleanser contains a specific smart delivery system to minimize any irritation that could come from using a daily AHA. With that being said, the brand specifically states that this product is best for experienced glycolic acid users, so we do not recommend this product to those who are just starting out with exfoliating acids, as this formula may prove to be too much for daily use.


Neostrata Pigment Controller Review

Neostrata Pigment Controller is an oil-free skin tone corrector and brightening formula that is said to promote a complexion that is smoother, more luminous, with enhanced radiance and more even tone. One of the key ingredients in this formula is NeoGlucosamine™ (acetyl glucosamine). Acetyl glucosamine is naturally found within the human body, for example, when acetyl glucosamine is combined with glucuronic acid, it forms hyaluronic acid, a major component of the extracellular matrix. NeoGlucosamine™ is a patented non-acid amino sugar that diminishes the appearance of fine lines and wrinkles while also alleviating discoloration for a more even skin tone. It gently exfoliates the skin to reveal healthy new cells. NeoGlucosamine™ is the ingredient solution for clarity of discolorations, firmness, and mild exfoliation.

Another key ingredient in Neostrata Pigment Controller is retinol (0.1%). After being absorbed by the skin, retinol is converted to retinoic acid, the active metabolite of vitamin A, which increases the production of collagen and promotes healthy cell turnover. Retinol is clinically proven to minimize the appearance of fine lines and wrinkles, improve uneven skin tone, restore skin firmness, and shrink the appearance of enlarged pores. One of the key brightening ingredients in this formula is ascorbyl glucoside, a stable water-soluble derivative of vitamin C. Vitamin C is a potent antioxidant that helps the skin combat free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin. Vitamin C also helps to prevent the development of dark spots on the skin by inhibiting tyrosinase, a key enzyme involved in the synthesis of melanin. Lastly, Neostrata Pigment Controller contains many brightening plant extracts, such as mallow extract, lady’s mantle extract, lemon balm extract, yarrow extract, and more.


Neostrata Brightening Eye Cream Review

Neostrata Brightening Eye Cream is a fragrance-free eye cream for all skin types that is said to reduce the appearance of dark circles under eyes, as well as restore a look of firmness and moisture for a smooth, bright appearance. Two of the key ingredients in this eye cream are gluconolactone and lactobionic acid, which are both classified as polyhydroxy acids (PHAs). Both of these ingredients are chemically and functionally similar to alpha hydroxy acids (AHAs), such as glycolic acid, which are known for their ability to exfoliate the skin. The key difference between PHAs and AHAs is that PHAs have a larger molecular structure, which reduces their ability to penetrate the skin. Ultimately, this decreases the risk of side effects, such as dryness, redness, and irritation. Plus, the reduced absorption into the skin does not make PHAs any less effective than AHAs.

Neostrata Brightening Eye Cream provides the delicate skin around your eyes with numerous soothing and hydrating ingredients, including arginine (amino acid), green tea leaf extract, algae extract, cucumber fruit extract, panthenol (provitamin B5), and sodium hyaluronate. Neostrata Brightening Eye Cream also contains tetrahexyldecyl ascorbate (vitamin C ester) and tocopheryl acetate (vitamin E ester), which both provide antioxidant effects. Antioxidants limit oxidative damage caused by free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin. Additionally, vitamin C is known to improve skin firmness, brighten skin tone, and reduce the appearance of dark spots, while vitamin E is known to strengthen the skin’s barrier. Lastly, Neostrata Brightening Eye Cream contains two peptides: palmitoyl tetrapeptide-7 and palmitoyl tripeptide-1. Peptides work by sending signals to cells to produce new collagen. Over time, increased collagen levels promote firmer skin with less fine lines and wrinkles.


Neostrata Ultra Smoothing Lotion Review

Neostrata Ultra Smoothing Lotion is a lightweight face and body exfoliating moisturizer and cell renewal treatment that is said to relieve dry, damaged skin, while preventing further damage on non-sensitive skin. It contains 8% glycolic acid and 2% citric acid, which are both alpha hydroxy acids (AHAs). AHAs exfoliate the skin by targeting corneocytes (dead skin cells that make up the stratum corneum) in a process called corneocyte desquamation. By enhancing their breakdown and increasing the separation of skin cells, the rate of cell turnover is increased, leading to smoother, brighter skin and a more even complexion. Furthermore, Neostrata Ultra Smoothing Lotion is specially formulated to provide a potent and precise delivery of glycolic acid while maintaining an optimal pH.

Neostrata Ultra Smoothing Lotion also contains a few moisturizing ingredients, such as arginine, glycerin, and mango seed butter. Both arginine (an amino acid) and glycerin are classified as humectants. A humectant is a hygroscopic substance that has a molecular structure with several hydrophilic (water-loving) groups. This structure allows humectants to attract moisture and draw that moisture into the skin’s surface, preventing it from evaporating. In addition, arginine is able to help synthesize components of the skin’s Natural Moisturizing Factor (NMF), such as ceramides, cholesterol, urea, and glycosaminoglycans. Together with the naturally-occurring lipids in skin, NMF components work to keep skin’s surface intact, supple, and hydrated. Mango seed butter functions as an occlusive emollient, which means it forms a physical barrier on the skin’s surface to lock in moisture. Overall, Neostrata Ultra Smoothing Lotion combines two exfoliating AHAs with moisturizing ingredients to restore a visibly smoother appearance to skin.


NeoStrata Smooth Surface Daily Peel Review

Neostrata offers an entire range of well formulated, highly potent products that focus on using the most well researched active ingredients to deliver results. One of their most well loved products is the NeoStrata Smooth Surface Daily Peel. Although NeoStrata offers a wide array of exfoliating products, each option offers something different. With the Smooth Surface Daily Peel, this product uses chemical exfoliants to deliver a powerful exfoliation in a gentle moisturizing cream formula. The ingredients list including 10% glycolic and citric acids to target a variety of skin concerns including fine lines and wrinkles, dullness and uneven skin tone. Glycolic acid is an alpha hydroxy acid with the smallest molecule size, meaning that they penetrate the skin the deepest. Because of this, you may find that this product is fairly intense and can only be used once or twice a week without causing any irritation. With that said, this product has been specially formulated to deliver the optimum amount of glycolic acid to the skin while simultaneously maintaining the ideal pH so that you get all of the benefits of this ingredient, without any redness or sensitivity.


NeoStrata Skin Active

When the natural process of aging causes the skin to sag and develop wrinkles, skin care lines like NeoStrata Skin Active promise to heal the skin and give it added support. However, before using any anti aging products, it’s important to understand how and why your skin ages. There are many facets to this process, including damage to the collagen support network, sun-induced hyperpigmentation, and a weakened moisture barrier. Therefore, any man or woman who is serious about anti aging skin care should speak with their dermatologist before using NeoStrata Skin Active. A trained skin expert can help you understand the causes that contribute to your skin aging the most, and the best ingredients to address the issue. Additionally, reading NeoStrata Skin Active reviews from consumers who are in your age range and have a similar skin type can also go a long way in assessing whether the company’s products are right for you.

NeoStrata Skin Active Triple Firming Neck Cream Review

The NeoStrata Skin Active Triple Firming Neck Cream was designed to reverse some of the main physical signs of aging including fine lines and wrinkles as well as dark spots and hyperpigmentation. This product contains three main active ingredients including pro-amino acids, as well as NeoCitriate and NeoGlucosamine, both of which are unique to NeoStrata. These ingredients work to boost collagen production, which can slow down as we age. Additionally, NeoGlucosamine gently exfoliates the skin in order to reduce the appearance of uneven skin tone or hyperpigmentation. Because this product contains exfoliating agents, the brand recommends applying this product once a day, ideally as part of your evening routine. This helps to ensure that you don’t experience any sensitivity or barrier damage due to overuse or over-exfoliation.


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