Skin Better Science Review: 10 Best Skin Better Science Products



Here at The Derm Review, we love brands that formulate their products based on science, so it’s no surprise that our team enjoyed reviewing the Skin Better Science products. 


1Carrot & Stick Review
-SkinBetter Science

Founded in 2016, Skin Better Science believes remarkable results can be achieved simply through purposeful product innovation. Their products are formulated to prevent and correct signs of aging, such as lines, wrinkles, hyperpigmentation, uneven skin tone, and more. 

But how well do the Skin Better Science products perform? To answer that question, we’ll have to discuss the formulation details, including the key ingredients in Skin Better Science products and the research that supports (or doesn’t support) their use in skincare.

We’ll also share some Skin Better Science reviews so that you can get an idea of what customers really think of these products.


Is Skin Better Science Worth The Money?

A common question about this brand is if the products are worth the cost. Skin Better Science products are expensive, for example, the Even Glow Regimen is $390.

In our opinion, Skin Better Science products aren’t worth the money, simply because there are other skincare brands that offer similar products that are less expensive.

One brand is Carrot & Stick, a clean skincare brand that perfectly balances the gentle nurturing of plants with the powerful results of innovative science.

Carrot & Stick intro bundles deliver great value for money because you can bundle 3 full-size products worth up to $240 for $88.

What’s Inside The Skin Better Products?

Skin Better is known for using evidence-based ingredients to formulate their products. Vitamin C, peptides, retinol, and alpha hydroxy acids (AHAs) make up the core ingredients for the Skin Better line. These ingredients should all be part of your skincare routine.

Vitamin C
We’ve been hearing for years that Vitamin C is the best anti-aging ingredient. Vitamin C is a potent antioxidant that protects the skin from free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin.

Skin Better Science Alto Defense Serum is an antioxidant serum that combines vitamins C and E, as well as 17 additional antioxidants. 

But our favorite Vitamin C serum is Carrot & Stick The Defence Serum. It contains 3 distinct types of Vitamin C that work together to help fight free radical damage. We recommend using it every morning.

As you age, your body’s production of collagen and elastin slows down. These two proteins are responsible for your skin’s structural support. As a result, the skin loses its natural plumpness and smoothness. 

While collagen is necessary for maintaining youthful-looking skin, the collagen protein is too large to absorb into the skin topically. That’s why applying skin care products that contain collagen won’t provide the anti-aging benefits you’re looking for.

This is where peptides come into action. Peptides are the building blocks of protein, and they are easily absorbed into the deeper layers of skin due to their smaller size. 

Skin Better Science InterFuse Treatment Cream Eye contains the targeted peptide (palmitoyl tripeptide-38), which is designed to smooth the appearance of crow’s feet almost immediately.

We recommend Carrot & Stick The Repair Serum. It contains 7 plant-based peptides to promote plumper and smoother-looking skin. It also has skin-loving ingredients like hyaluronic acid and niacinamide.

Retinol is the go-to anti-aging ingredient recommended by dermatologists and skin experts. While retinol provides many benefits to the skin, it’s also known to cause side effects like skin dryness and irritation. 

Skin Better Science AlphaRet Overnight Cream is formulated with the brand’s patented AlphaRet technology, which successfully combines a retinoid and an AHA (glycolic acid) for effective and tolerable skin rejuvenation. Both of these ingredients help to increase cell turnover while also stimulating collagen production. The result? Brighter, firmer, smoother skin.

It’s best to use retinoids at night. We recommend this retinoid oil serum. It contains Hydroxypinacolone Retinoate, an ingredient that provides similar benefits with less irritation.

What Are The Top 10 Best Skin Better Science Products?

Skin Better Science offers a collection of anti-aging moisturizers, serums, sunscreens, eye creams, cleansers, and exfoliants. Here’s a breakdown of the top 10 best Skin Better Science products.


Skin Better Science AlphaRet Overnight Cream

Skinbetter Science debuted in 2016 and the company says its products are “backed by decades of rigorous clinical research.” The product line is only available through its network of physicians at dermatology offices as well as select medical spas. Skinbetter Science describes its philosophy as being rooted in science—“We believe remarkable results can be achieved simply, through purposeful product innovation, which is why we leverage advanced chemistry to help skincare products do more.”


It’s formulated with the brand’s patented AlphaRet technology, which successfully combines a retinoid and an AHA (glycolic acid) for effective and tolerable skin rejuvenation.

Both of these ingredients help to increase cell turnover while also stimulating collagen production. The result? Brighter, firmer, smoother skin. 

Bottom Line: An anti-aging night cream that combines an AHA (glycolic acid) with a retinoid to rejuvenate skin. 


Skin Better Science Intensive AlphaRet Overnight Cream

Like the AlphaRet Overnight Cream, this skincare cream features a unique ingredient that is made up of a retinoid combined with an alpha hydroxy acid (AHA).

The only difference is that this formula includes a higher concentration of glycolic acid, giving you a more intense rejuvenation (hence the name). 

According to the brand, this cream should significantly reduce the appearance of wrinkles in as little as four weeks, with little-to-no irritation.

Bottom Line: This product is similar to the Skin Better Science AlphaRet Overnight Cream, but contains a higher concentration of glycolic acid. 


Skin Better Science Even Tone Correcting Serum

A hydroquinone-free serum that brightens and evens the appearance of skin tone thanks to ingredients like alpha arbutin and hexylresorcinol.

Both of these ingredients improve hyperpigmentation through inhibition of tyrosinase. Tyrosinase is a key enzyme involved in the synthesis of melanin, the pigment that gives skin color. By inhibiting tyrosinase, alpha arbutin, and hexylresorcinol help to reduce abnormal pigmentation associated with aging and exposure to UV light.

There’s also hydrating ingredients like hydrolyzed hyaluronic acid and bisabolol, as well as ingredients to strengthen the skin barrier like ceramides. 

Bottom Line: This Skin Better Science serum can help brighten the complexion and reduce the appearance of dark spots. 


Skin Better Science Trio Rebalancing Moisture Treatment

This facial moisturizer includes a plethora of hydrating ingredients, such as glycerin, hydroxyethyl urea, sodium lactate, sodium PCA, urea, and many more. These ingredients help to increase the skin’s hydration by replenishing the Natural Moisturizing Factor (NMF).

The NMF is primarily composed of free amino acids and various derivatives of these amino acids, for example, PCA, urocanic acid, and inorganic salts, sugars, as well as urea and lactic acid.

The role of the NMF is to maintain adequate skin hydration. The NMF can become depleted with age and also from routine exposure to sensitizing ingredients like drying cleansing agents and denatured alcohol. This leads to visibly dry, tight-feeling, flaky skin.

Thus, by using products that help to replenish NMF — such as Skin Better Science Trio Rebalancing Moisture Treatment — the skin will be better hydrated. Ultimately, the skin will look and feel healthy, smooth, and supple. 

Plus, the formula also contains ingredients to strengthen the skin barrier, such as cholesterol and ceramides, as well as emollients like squalane and caprylic/capric triglyceride to soften skin and lock in moisture. 

Bottom Line: Skin Better Science Trio Rebalancing Moisture Treatment is an excellent moisturizer because it combines ingredients to replenish the NMF with emollients and barrier-strengthening ingredients. 


Skin Better Science InterFuse Treatment Cream Eye

This Skin Better Science eye cream has a silky texture that absorbs into the skin quickly without feeling greasy or sticky. 

We love that the formula contains a decent amount of niacinamide, which is one of the best skincare ingredients, in our opinion. And there’s research to back it up.

For example, a publication in the Journal of Clinical and Aesthetic Dermatology; states that niacinamide can repair the skin barrier and improve skin moisture, as well as reduce inflammation, blotchiness, hyperpigmentation, and wrinkling. Pretty impressive, right?

And like most eye care products, the Skin Better Science eye cream includes caffeine. We all know caffeine can help wake up our minds, but did you know caffeine also helps combat dark circles and puffiness when applied topically?

After caffeine penetrates the skin barrier, it’s absorbed by the surrounding blood vessels, causing vasoconstriction while also stimulating blood flow. This helps in reducing the amount of blood that accumulates under the eyes (a major factor that contributes to dark circles). 

Caffeine also acts as a diuretic and can help to relieve water retention, a major cause of puffiness under the eyes.

Last but not least is the targeted peptide (palmitoyl tripeptide-38), which is designed to smooth the appearance of crow’s feet almost immediately.

Bottom Line: Skin Better Science eye cream includes key ingredients like niacinamide, caffeine, and an anti-aging peptide to brighten and firm the skin around the eyes. 


Skin Better Science Alto Defense Serum

This antioxidant serum helps to protect your skin from free radical damage with the potent antioxidants vitamins C and E, as well as a whopping 17 additional antioxidants. 

Using an antioxidant serum is important because free radicals can damage important cellular components, including collagen. Damaged collagen manifests as signs of premature skin aging, including wrinkles, lines, and sagging skin. 

There are also hydrating ingredients like hydrolyzed hyaluronic acid and bisabolol, as well as ingredients to brighten the complexion, such as licorice and turmeric root extract. 

Bottom Line: An antioxidant serum that protects against environmental free radicals while also hydrating and brightening skin. 


Skin Better Science sunbetter TONE SMART SPF 68 Sunscreen Compact

This is a 100% mineral sunscreen that combines zinc oxide and titanium dioxide to provide broad-spectrum SPF 68 protection.

These sunscreen ingredients are formulated into a tone-adapting, silky smooth compact that provides a hint of blendable color. It acts as a primer under makeup and you can layer it for additional coverage.

Plus, this Skin Better sunscreen provides benefits beyond UV protection, including blue light, pollution, and infrared radiation.

Bottom Line: A 100% mineral sunscreen compact that acts as a primer under makeup and provides a hint of blendable color. 


Skin Better Science sunbetter SHEER SPF 56 Sunscreen Stick

Another 100% mineral sunscreen with zinc oxide and titanium dioxide that’s formulated into a weightless, transparent, and easy-to-apply stick. These ingredients provide broad-spectrum SPF 56 protection against UVA (aging) and UVB (burning) rays.

The formula has a very silky texture thanks to a combination of several different silicones and emollients. However, unlike the sunbetter Sunscreen Compact, this product does not provide any color. 

Bottom Line: A 100% mineral sunscreen stick that creates a silky, sheer effect when blended into the skin. 


Skin Better Science Hydration Boosting Cream

This dual-action moisturizer delivers immediate and long-lasting hydration, creating a velvety finish on the skin.

We noticed that this formula is packed with ceramides, the waxy lipid molecules that are naturally produced by the skin and are vital in supporting the stratum corneum (outer layer of skin). 

A properly functioning stratum corneum is essential for healthy skin as it maintains epidermal hydration and serves as a barrier that responds to environmental stressors, infections, irritants, and allergens.

Applying products that contain ceramides — such as Skin Better Science Hydration Boosting Cream — can help to replenish ceramide levels, thus restoring the skin’s natural barrier. 

The formula also includes plenty of humectants (betaine, xylitol, glycerin, beta-glucan, and more) to draw moisture into the skin, as well as the antioxidants vitamins C and E to protect against free radicals. 

Bottom Line: A facial cream that’s rich in ceramides, humectants, and antioxidants to hydrate and protect skin. 


Skin Better Science Cleansing Gel

This is a mild, foaming gel cleanser that gently and thoroughly cleanses the skin and removes makeup. Like most cleansers, this formula includes surfactants as the key ingredients. 

A surfactant molecule contains one end that is hydrophilic (attracted to water) and one end that is lipophilic (attracted to oil). This allows surfactants to attract and suspend oils, dirt, and other impurities that have accumulated on the skin and wash them away. 

These surfactants are combined with hydrating and soothing ingredients, such as aloe vera, chamomile, and cucumber extract. 

Bottom Line: A mild, foaming gel cleanser that gently cleanses skin, removes makeup, and hydrates. 

Is Skin Better Science AlphaRet Overnight Cream Right For You?


Before purchasing the Skin Better Science AlphaRet Overnight Cream, here’s a summary of the most important factors to consider:

  • Key ingredients? Glycolic acid, retinoid
  • Skin type? All skin types
  • Texture? Lightweight cream
  • Fragrance? No
  • Cruelty-free? Yes
  • Cost? $125 USD for 1 oz

How Much Do Skin Better Science Products Cost?

Skin Better Science products are priced on the higher end; they are much more costly than drugstore products, but they aren’t outrageous. For example, Skin Better Science AlphaRet Overnight Cream costs $125 USD for 1 oz, while the InterFuse Treatment Eye Cream costs $105 for ½ oz. 

Where to Buy Skin Better Science Products?

Skin Better Science products can only be purchased by the company’s authorized physicians. Once a customer has purchased products from an authorized physician, they can register to buy additional products directly from the website.

What is The Skin Better Science Return Policy?

The Skin Better Science return policy states, “We strive to exceed the expectations of our customers with our products and dedicated service. We stand behind our products and are committed to providing customers with the most effective and highest quality professional skincare products on the market. If the product you purchased at did not meet your expectations, please feel free to contact our Account Concierge Team.”

Is Skin Better Science Cruelty-Free?

Yes, Skin Better Science is cruelty-free. 

Is Skin Better Science Vegan?

Skin Better Science may offer some products that are suitable for vegans, but this is not a 100% vegan brand. 

Skin Better Science Reviews

One way we rate products on our review lists is by looking at what the customers have to say after they’ve tried the product. 

Unfortunately, Skin Better Science does not display customer reviews on their website. This is a shame because the real proof of how well a product performs is in what the customer has to say after they’ve tried the product.

But we did take a look at to evaluate Skin Better Science reviews. There’s a handful of reviews for the popular AlphaRet Overnight Cream, and all the reviews are 4 and 5 star ratings. 

For example, one review says, “I have used this for a month now. I use it as the last step in my routine, at night. When I wake up, my skin is radiant. It is the only retinol product I can use every night without any dry skin or flakiness. In addition it had AHA’s in it that help exfoliate. This product definitely has multiple benefits, especially since my skin feels moisturized as well.”

While there aren’t very many Skin Better Science reviews from customers, this brand has received plenty of editorial coverage and awards. 

For instance, the AlphaRet Overnight Cream has won 8 awards, including the 2021 NewBeauty Beauty Awards and 2021 InStyle Best Night Cream.

In a 2018 Vogue round up on best eye creams, Francesca Fusco, M.D. named SkinBetter Science Interfuse Eye Cream one of her favorites due to the “neuro calming peptide that has a wrinkle diminishing effect.”

Other Skin Better Science products have been featured in Elle, In Style, O magazine, New Beauty, Allure, PopSugar, and more. 

Our Verdict

Overall, we think that Skin Better Science products are formulated well with a combination of evidenced-based ingredients with proprietary ingredients. 


  • Products contain evidenced-based ingredients (AHAs, retinol, hyaluronic acid, etc.)
  • All Skin Better Science products are paraben free, fragrance free, and dye free
  • Skin Better Science is cruelty free


  • High cost
  • Very few Skin Better Science reviews from customers

What Are Some Alternatives to Skin Better Science Products?

If you’re looking for skincare products to address the signs of aging, we recommend Carrot & Stick. Carrot & Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin. We recommend The Repair Serum, followed by The Moisturizer.

J Clin Aesthet Dermatol. 2010 Feb; 3(2): 22–41



Carrot & Stick

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  • DR Original review: Dec 18, 2023. Reply

    Here’s a lost of FAQ about Skinbetter Science.

    What’s the best skinbetter sunscreen?
    skinbetter tone smart, since it is mineral. So it is safe for the planet and your body.

    If you are allergic to mineral sunscreens, you can try sunbetter SHEER SPF 56 Sunscreen Stick. They even make an spf 70 version, but 56 is more than suffieent.

    Is skinbetter orth the price?
    It’s a great product but it is not worth the price.
    Products like mystro skinbetter  will cost you hundreds.

    Which skinbetter promo code should I use?
    We recommend signing up to their newsletter at the bottom of the homepage. That way you can look our for the best savings. You can also wait for skinbetter sale.

    What’s the best skinbetter moisturizer?
    If you have dry skin, I recommend Trio Rebalancing Moisture Treatment.

    What about the best cleansers?

    Both skinbetter cleansing gel and skinbetter oxygen wash

    What is a good skinbetter retinol cream?
    Definitely AlphaRet Overnight Cream

    They have a number of eye creams. What is the best eye cream in this range?
    skinbetter eye max or skinbetter interfuse eye cream.

    If you are looking for an eye gel, Instant Effect Gel EYE is a great gel eye cream

    Where to buy skinbetter science 
    The good news is that you can purchase directly from their website.

    Which is better? Skinbetter vs skinceuticals.
    Both make efficacious products. Both brands are owned by L’oreal. Skinbetter is a bt more innovative and easier to purchase.

    What are some other progressional brands like Skinbetter?

    Alastin Skincare, Zo Media, Skinmedica. Elastin and Skinbetter are the newer brands.

    What is the skinbetter order of application?
    If you’re trying to build your skincare routine remove these steps.

    Start off with cleansing.
    Follow with a toner. You can skip this step if you want a simple routine.

    Then use a serum.

    Follow this with a cream.

    And when you go out, always use spf.

    Keep your skincare regimen simple, and you will be rewarded with radiant skin.

    Is Skinbetter pregnancy safe?
    Avoid ingredients like retinol when you are pregnancy.

    What skinbetter dupes?
    We recommend avoid any dupes. They are not safe.

    skinbetter night cream 
    If you can afford to blow over $100 on a cream, SkinBetter Science AlphaRet Overnight Cream FACE is a good choice.

    They also make travel size products, to make it easier for travel.
    SkinBetter Solo Hydrating Defense MEN is a good product for men.

    Is Skinbetter cruelty free?
    Skinbetter does not test on animals. However, they are part of L’oreal. L’oreal does retail their products in countries that require animal testing, like China.

    What are their most popular skincare products?

    Trio Rebalancing Moisture Treatment
    Tone Smart Spf
    Techno Neck Perfecting Cream
    Refresh Oxygen Infusion Wash 1
    Refresh Hydration Boosting Cream
    Refresh Detoxifying Scrub Mask
    NEW A Team Duo Kit
    Interfuse Treatment Cream Face
    Interfuse Treatment Cream Eye
    Interfuse Intensive Treatment Lines
    Instant Effect Gel- Eye
    EyeMax Alpharet Overnight Cream
    Even Tone Correcting Serum
    Cleansing Gel
    Alto Defense Serum Face
    Alto Advanced Defense And Repair Serum
    Alpharet Overnight Cream Face
    AlphaRet Intensive Overnight Cream
    Alpharet Exfoliating Peel Pads 30 Pack
    Alpharet Clearing Serum

  • lynsey Original review: Aug 08, 2023. Reply

    You should reach out to their customer service as they are quite responsive. I believe only the oxygen wash foams up and the cleansing gel does not.

  • Kelly papagikos Original review: Feb 14, 2022. Reply

    I bought the wash because I loved it and have the whole set when I bought the second one it does not foam up and it smells real bad don’t know if it’s old or not I also bought the alphahydroxy the packaging fell on the floor and broke my bottle now it does not pump very upset I spent a lot of money for something that looks good but doesn’t last in the packaging

  • Denise Quercia Original review: Dec 13, 2021. Reply

    At 64 I have used lancome products for most of my life. last 8 years medical grade from dr. Offices. These are the first skin care products that I have almost canceled a treatment for !!!! 2 months with skin better products and I’m still happy!

  • Linda fortin Original review: Feb 20, 2020. Reply

    I purchased the Rejuvenate Trio moisture cream for my face , I have tried everything out there just about band this is definitely the one for me , it is absolutely wonderful !! 5 star for sure !!!

  • Your Review
    User Rating: 3.5 (2 votes)

    SkinBetter Science AlphaRet Night Cream Review

    If you’re looking for a multi-tasking serum for your night time routine, the SkinBetter Science AlphaRet Night Cream could be an excellent option. This product contains Alpha Hydroxy Acids or AHA’s, as well as retinol to gently but effectively exfoliate the skin, increase cell turnover, and reduce signs of premature aging. Retinol and AHA’s are some of the most well researched active ingredients in skincare, making this product an excellent choice for those of you who like to do your research before investing in a skincare product. But the benefits don’t stop with these two ingredients. This formula also contains multiple types of peptides as well as ceramides which help to stimulate collagen and maintain healthy skin barrier function. With such a powerful and packed formula, we highly recommend incorporating this product into your routine slowing, starting off with a couple of times a week rather than every evening. In addition, since this product does contain actives, you should also incorporate a sunscreen into your morning routine as these ingredients can make your skin more sensitive to sun damage.


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