Perricone Reviews - The Dermatology Review

Perricone Reviews

Skin Care Reviews

09.28.18AD DISCLOSURE

Dr. Nicholas Perricone may not be the first celebrity dermatologist to launch his own skincare line (Dr. Howard Murad and Dr. Frederic Brandt also jumped in) but he was one the first to embrace holistic healthcare and wellness. His line has been around for 20 years and has expanded beyond skincare to include “no makeup” makeup as well as supplements. Here’s a closer look at the brand, what it stands for, and does it really work?

Perricone Reviews

Who is Dr. Perricone?

Dr. Perricone was an assistant clinical professor of dermatology at the Yale School of Medicine when he published his first book, “The Wrinkle Cure.” In this book he laid out his philosophy of aging. He rejects the idea that fine lines and wrinkles are an inevitable part of getting older, and has also said he doesn’t believe in using injectables on the face. Dr. Perricone believes that aging is an inflammatory disease that happens at the cellular level, but it can be controlled by what you eat. His theory is that when inflammation is controlled, skin can maintain a youthful look and the cornerstone of this concept is a diet rich in Omega-3 fatty acids.

What are the Best Skin Care Products of 2020?

Dr. Perricone’s three day and 28 day diet plan focus on eating antioxidant rich foods, high-quality proteins and vitamin supplements combined with topical skincare to fight the signs of aging. His diet includes food such as wild salmon, turkey, almonds, beans, pomegranates and yogurt.

Perricone Reviews

His other books include “Ageless Face, Ageless Mind”; “The Perricone Prescription”; “Forever Young”; and “Dr. Perricone’s 7 Secrets to Beauty, Health, and Longevity: The Miracle of Cellular Rejuvenation.” Dr. Perricone no longer practices dermatology and focuses on his business instead. The company was initially called NV Perricone but was rebranded to be named Perricone MD. The packaging was also changed to follow a color coded system. As of 2008, the company had generated $50M in revenue.

What Does Perricone MD sell?

Perricone MD sells a wide range of skincare products as well as makeup and supplements. The brand debuted in 1997 with the goal of treating inflamed skin. In 2003, the line was available on QVC and proved to be a hit. One of the brand’s standout products was the Cold Plasma Cream which launched in 2009. The “No Makeup” makeup line launched in 2014 to rave reviews, and Dr. Perricone is created for being a pioneer of “Cosmeceuticals,” which is makeup that is good for you. The newest line to join the range is the Essential Fx, which includes vitamin F, which is found in argan, rosehip and chia.

The Perricone MD line features multiple collections, including the High Potency Classics, Vitamin C Ester, Hypoallergenic, Cold Plasma Plus, Essential Fx, Neuropeptide, No: Rinse, No Makeup, Masks, Pre:Empt Series and H2 Elemental Energy.

Here’s a closer look at some of the brand’s bestsellers.

Perricone No Makeup: This unique product is a hybrid foundation and a serum, and gives natural looking coverage. It’s also lightweight and helps minimize the appearance of pores, and also protects skin with an SPF 30.

Vitamin C Ester Brightening Serum: The powerhouse ingredient here is vitamin C ester, a more gentle version of vitamin C. The serum delivers a dose of radiance while helping to even out skin tone.

MD Supergreens Supplement Powder: Packed with vitamins C and A, as well as riboflavin, vitamin B6 and folic acid, these single serving packets also contain probiotics and are meant to promote healthy aging.

Cold Plasma Neck & Chest Broad Spectrum SPF 25: The Cold Plasma collection has earned cult favorite status. It’s designed to target sagging neck skin and tone this area, while improving skin texture.

Cocoa Moisture Mask: Another cult favorite product, this mask smells like chocolate and delivers a deep dose of hydration thanks to hyaluronic acid, cocoa extract and DMAE, which is meant to lift sagging skin.

High Potency Classics Face Finishing & Firming Moisturizer: The popular High Potency collection uses ingredients such as vitamin E and kukui nut oil in products such as this deeply hydrating moisturizer.

CBX Lightweight Moisturizer: Designed for men, this lightweight moisturizer is designed to be absorbed quickly. It contains phytocannabinoids, which are derived from the hemp plant.

What are Some of the Ingredients Found in Perricone MD?

Perricone products are formulated with a blend of well known ingredients such as hyaluronic acid, which holds up to 1,000 times its weight in water, and lesser known ones such as vitamin F and DMAE. Vitamin F is the cornerstone of Perricone MD’s new Essential Fx line. Vitamin F is an unsaturated fat like Omega 3, 6 and 9 and is found in chia seed oil, flaxseed oil, macadamia seed oil, pumpkin seed oil and sardines. The line also contains acyl-glutathione, a naturally occurring antioxidant that decreases with age, stress and environmental aggressors.

Perricone Reviews

The Cold Plasma Dub-D line is based around DMAE, or dimethylaminoethanol. This is naturally produced in the brain and also found in oily fish such as anchovies and sardines. DMAE in skincare is thought to boost skin health by boosting cell function. It is also found in the Cocoa Mask.

The Neuropeptide line harness the power of neuropeptides, which Perricone MD explains as “powerful, protein-like building blocks that offer the ultimate visible antidote to wrinkles, sagging, dullness, and discoloration. Neuropeptides encourage surface skin cells to work together via a unique chemical structure.”

Other more commonly used ingredients in Perricone MD products include nourishing vitamin E; cold pressed kukui nut for a dose of moisture; olive leaf extract for hydration; and citrus extract for gentle exfoliation.

Where Are Perricone MD Products Sold?

Perricone MD products are sold at major department stores such as Nordstrom, Macys and Neiman Marcus, as well as specialty makeup stores such as Blue Mercury, Sephora and Ulta. It is also sold on QVC, Amazon and Walmart.

How Much are Perricone MD Products?

Perricone MD products are on the pricier side of the spectrum without nearing stratospheric prices. The Face Finishing & Firming Moisturizer retails for $69, while the No Makeup Foundation Serum is $69. The Lightweight Moisturizer for men is $59. The Cold Plasma collection is among the most expensive- the Cold Plasma Plus Duo, which contains the face and eye cream, retails for $199. The products are sold individually as well as in kits.

Do Perricone MD Products Work?

Perricone products have been best sellers for around 20 years and many of the products have achieved cult favorite status – which suggests the brand is doing something right. Many Perricone products have scooped up beauty industry awards as well. The No Makeup Instant Blur powder received a coveted award in 2017 from O Magazine, which called it a “Magic Eraser for your face.” Perricone’s Pre:Empt Oil-Free Hydrating Cream won Allure’s Best Facial Moisturizer for Oily Skin in 2016, while the Perricone MD Photo Plasma Anti-Aging Moisturizer won a New You Beauty Award in 2017. One of the most prestigious awards was from Good Housekeeping magazine, which named the Perricone MD Photo Plasma Moisturizer Broad Spectrum SPF 30 one of the beauty breakthrough products of 2018. The Good Housekeeping Lab found that the cream increased skin’s hydration by 30%, improved the look of pores by 8%, and texture by 11%, according to the lab’s measurements.

Every product on the Perricone website lists clinical results. For the Cold Plasma Advanced Serum Concentrate, the company says 100% showed a significant improvement in lines & wrinkles, while 97% showed a significant improvement in pore size. The rose scented Face Finishing & Firming Moisturizer also has similar results – the company says 97% agreed skin looked healthier, 91% saw a reduction in the appearance of fine lines and wrinkles and 91% agreed skin had a radiant glow.

Websites such as QVC, Sephora and Amazon offer a wider look at the products’ popularity and efficacy, but for the most part, the sites do not have a high number of reviews for Perricone products. The DMAE Firming Pads, a no rinse toner, gets mixed reviews on QVC from 20 users. One customer complained about the quality- “Dry, dry, dry! For this price I would expect a little more moisture in the product. I know it wasn’t suppose to be dripping with product but come on…. Dr. Perricone your heart is in the right place but your product fails frequently” while another one says “I love this product. When you meet an old friend who you have not seen in a while and they say to you “keep doing what you are doing, you look great”, I will take that as a verification of what I thought about my skin. So much better than before.”

Perricone products on Sephora tend to get higher numbers of reviews. The Cold Plasma Plus+ Neck & Chest Broad Spectrum SPF 25 gets a 4.5 star rating from 223 reviews; 139 of those are five stars. One reviewer says “I started seeing results as soon as I began using the product” while detractors criticize its “filmy feeling” and complain that it’s “not worth the price tag.” The No Makeup Foundation Broad Spectrum SPF 30 has over 1,000 reviews which give it 3.9 out of five stars. Some users call it “The BEST foundation ever!!!” and “This is a great product! Very natural–smooths out my un-even redness but reveals my freckles.” Users who are not fans complained that the foundation didn’t offer enough coverage or didn’t work well with oily skin.

What Are Alternatives to Perricone MD Products?

Perricone MD products come with a hefty price tag which may not be for everyone- or perhaps the products just don’t react well with your skin. There are a few other companies to consider.

Formulyst focuses on long-term and effective skincare, and the product line addresses everything from wrinkles to dark spots and dry skin. If you have anti-aging concerns, stock up on Formulyst’s Anti-Aging Night Cream ($59). It’s packed with the gold standard ingredient for softening the look of fine lines, retinol, which is derived from vitamin A. What makes this formula different is that it contains a high dose of retinol but it’s also packed with ultra-soothing and hydrating safflower seed oil and jojoba to lock moisture in and minimize any potential irritation.

Formulyst Retexturing and Perfecting Serum ($39) is powered by gentle but effective alpha hydroxy acid (AHA) and beta hydroxy acid (BHA) which works to dissolve skin cells. Packed with plant based acids, this serum sloughs off dead skin cells, leaving behind fresher, smoother looking skin. Formulyst’s Pro-Collagen Serum ($59) contains a highly concentrated mix of peptides and proteins, derived from seaweed, wheat and soy, to help tackle these signs of aging. Apply a few drops of this hydrating serum to help skin look smoother and younger.

If you don’t want to build your own skincare regimen, consider a skincare kit from Advanced Dermatology. The Advanced Dermatology line includes everything needed to address the signs of aging. The system can help diminish the appearance of wrinkles, reduce dark spots and hyperpigmentation. The regimen also works to minimize redness, even out skin tone and improve the appearance of eye bags and dark circles. The kit includes a cleanser, serum, anti-wrinkle treatment, moisturizer, day cream and eye cream- in other words, everything you need for glowing, beautiful, healthy skin.

THE BEST SKIN CARE LINES 2020

1

Formulyst

The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Many of the Formulyst’s products harness the power of plant and citrus extracts as well as gold-standard workhorses such as retinol. Read More
2

Advanced Dermatology

The Advanced Dermatology skin care regimen addresses the most pressing aging concerns. It can be used by men and women in their 20s, 30s, 40s, 50s, 60s and beyond. This award-winning system can help diminish wrinkle appearance, reduce dark spots and hyperpigmentation, fade away redness, even out skin tone and improve the appearance of eye bags and dark circles. Some of the standout products in this line include the Super Youth Serum, Complete Age Defense and Anti-Wrinkle Firming Night Treatment. Read More

Perricone MD Vitamin C Ester 15 Review

The Perricone MD Vitamin C Ester 15 is a great place to start if your looking to incorporate vitamin C into your routine. Vitamin C is one of the most well known and well supported active ingredients within the skincare industry. But it can also be a challenge, both as a skincare consumer as well as a formulator. Pure ascorbic acid or vitamin C is extremely unstable and can oxidize overtime in the presence of water and/or oxygen. Pure vitamin C can also be very sensitizing to those who are new to vitamin C. As an alternative, many brands have turned to vitamin C esters in relatively high percentages to create products that are effective and produce many of the same results as an ascorbic acid based product, without compromising on the condition of your skin or the efficacy of the product. The Perricone MD Vitamin C Ester 15 for example, uses a 15% concentration of ascorbyl palmitate to help with everything from skin brightening and smoothing to addressing stubborn dark spots and discoloration. Plus, to take preservation and efficacy even further, this product comes packaged as a pack of 4 individual wrapped, 10mL tubes which you can open and use each week.
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Perricone MD No Makeup Foundation Review

Perricone MD No Makeup Foundation is a sheer, luminous foundation plus sunscreen that is said to create a more uniform complexion that visibly reduces dark spots and uneven skin tone over time, leaving a hydrating dewy finish. It is available in 8 different shades so that you can choose the one that best matches your skin tone. The active sunscreen ingredient in this foundation is zinc oxide, a mineral sunscreen that works by blocking or deflecting UV light, rather than being absorbed by the skin. Zinc oxide provides broad spectrum protection, which means it defends against both UVA and UVB rays. One disadvantage of this foundation is that it is only rated SPF 20, when SPF 30 or higher is recommended for adequate protection.

Another key ingredient in the Perricone MD No Makeup Foundation is Bellis perennis (daisy) flower extract, which contains a compound called arbutin. Arbutin is a glycosylated hydroquinone that has the ability to inactivate tyrosinase. Tyrosinase is a key enzyme involved in the synthesis of melanin, the pigment that gives skin color and also contributes to the formation of undesirable dark spots. Therefore, by inhibiting tyrosinase, the daisy extract in Perricone MD No Makeup Foundation may be able to reduce abnormal pigmentation associated with aging and exposure to UV light. A final key ingredient to point out in the Perricone MD No Makeup Foundation formula is Matrixyl™ 3000, a combination of the matrikines palmitoyl tripeptide-1 and palmitoyl tetrapeptide-7. Matrikines are messenger peptides that provide anti-aging benefits by signaling to cells to produce more collagen, resulting in a healthier, more youthful complexion.

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Perricone MD Intensive Pore Minimizer Review

Pores can be one of the most misunderstood skin concerns out there, especially when it comes to pore visibility. Despite popular belief, pores don’t actually grow or shrink based on external factors. They also don’t open and close. In fact, most of your pore size and appearance has to do with your genetic makeup. So armed with this knowledge, what can we do if were still not too thrilled with the appearance of our pores? Well, there are products out there like the Perricone MD Intensive Pore Minimizer which help to minimize the appearance of your pores as well as encourage clear and clean pores, free of blackheads, whiteheads and bad bacteria. The two main ingredients in this formula include DMAE and salicylic acid, both of which help to gently exfoliate, purify and diminish the appearance of pores without oversensitvizing or stripping your skin of its natural oils. These types of treatments help to make sure that your skin is freshly exfoliated without being too dry so that your pores look as small and clear as possible.
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Perricone MD Vitamin C Ester Serum Review

Perricone MD Vitamin C Ester Brightening Serum is a multi-tasking formula that targets uneven skin tone and discoloration. It is claimed to promote the appearance of collagen-rich skin by visibly smoothing, brightening, and minimizing discoloration. This serum contains tetrahexyldecyl ascorbate, an ester of hexyldecanol (synthetic fatty alcohol) and ascorbic acid (pure vitamin C). Tetrahexyldecyl ascorbate is oil-soluble, highly stable, more potent, and less irritating than other forms of vitamin C. Once tetrahexyldecyl ascorbate is absorbed into the skin, it is converted to ascorbic acid, which provides several benefits. Ascorbic acid is a potent antioxidant that protects the skin from free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin. Ascorbic acid also has the ability to improve skin firmness, brighten skin tone, and reduce the appearance of dark spots.

Perricone MD Vitamin C Ester Brightening Serum also contains the key ingredients squalane, hydrogenated lecithin, and rosemary leaf extract. Squalane is a saturated and stable hydrocarbon that mimics squalene (note the e) that is naturally found within the skin, resulting in softer and better hydrated skin. Hydrogenated lecithin is the product of controlled hydrogenation (addition of hydrogen) of lecithin, a natural fatty substance. Hydrogenated lecithin functions as an emollient and a penetration enhancer. Rosemary leaf extract is rich in antioxidants like carnosic acid and rosmarinic acid, which protect the skin from free radicals. With the highly stable, potent vitamin C ester combined with antioxidants and botanical extracts, Perricone MD Vitamin C Ester Brightening Serum should help to brighten, firm, protect, and hydrate the skin.
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Perricone MD Pre:Empt Skin Perfecting Serum Review

The Perricone MD Pre-Empt Skin Perfecting Serum was designed to serve as a powerful and potent antioxidant serum. The star ingredient blend within this product is the unique Nrf2 Antioxidant Support Complex. This patented formula was developed to help protect the skin’s natural lipid barrier and preserve the appearance of smooth, hydrated and even toned skin. This product contains an array of botanical extracts including green tea, turmeric, olive leaf and cress sprouts to help brighten and smooth the skin while simultaneously protecting it from damage. In a four week consumer test, 90% of participants noticed that their skin felt firmer, while 88% agreed that their skin looked smoother, tighter and brighter overall.
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Perricone MD Hydrating Booster Serum Review

The Perricone MD Hydrating Booster Serum was created in order to address dull and dehydrated skin. This hyaluronic acid-based serum helps to plump and smooth the skin. But unlike other hyaluronic acid based serums on the market, this product also contains ingredients that targets the appearance of wrinkles, enlarged pores and redness. Some of these key ingredients include a stabilized form of vitamin C, and the H2 Energy Complex, which is unique to Perricone MD. These two ingredients target different skin concerns. Vitamin C works to brighten the skin, reducing the appearance of hyperpigmentation and other formulas of discoloration. The H2 Energy Complex on the other hand is described as an antioxidant-rich mineral complex that was designed to nourish the skin and re-energize simultaneously. Because of these two ingredients, we’d recommend this product for those of you who are looking for a hydrating serum that offers a little bit extra in terms of active ingredients.
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Perricone MD High Potency Eye Lift Review

The Perricone MD High Potency Eye Lift is one of the classic cult favorite products that Perricone MD has been offering consumers for years. This eye serum aims to specific target loss of firmness and elasticity as well as dark circles. But how does this formula address those concerns? The High Potency Eye Lift provides vital hydration that helps to plump the skin, thereby reducing fine lines and wrinkles around the eyes. The formula behind this product contains hyaluronic acid, DMAE and squalane in order to deeply nourish and visibly firm the skin. In clinical trials, 86% of participants saw improvement in overall appearance of eye area, and that same 86% of participants reported that their skin felt and looked smoother after 28 days.
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Perricone MD Firming Neck Therapy Review

The Perricone MD Restorative Neck & Chest Therapy Broad Spectrum SPF takes some of the same powerful actives that are typically reserved for skincare and uses them to help nourish and protect your neck. After 20 years of research, this formula offers the most advanced firming solution available for your neck and chest area. The resulting cream helps to smooth crepey, fragile skin, reduces sagging, firms skin, fades the appearance of wrinkles and fine lines, and corrects signs of sun damage and hyperpigmentation. Vitamins B3 and C help to brighten, soothe and correct the skin, while SPF 25 continuously protects the skin from further damage caused by environmental stressors. Additionally, neuropeptides help to fight against wrinkles,stimulating collagen production and promoting healthy skin cells.
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Perricone MD Face Finishing Moisturizer

Looking at the aggregated ratings and reviews for Perricone MD Face Finishing Moisturizer, it’s easy to become optimistic about this face moisturizers. Packed with antioxidants and cutting edge ingredients like DMAE, the manufacturer claims this cream can significantly boost hydration in the skin and repair skin damage. However, at a cost of $75 for just two ounces, Perricone MD Face Finishing Moisturizer is not the most affordable face cream on the market. This dynamic makes it imperative for the cost-conscious consumer to evaluate the tradeoff between the price, and the possible improvement in the skin’s appearance. To make this assessment, it’s vital to look at the ingredients, analyze your unique skin needs, and read Perricone MD Face Finishing Moisturizer reviews from consumers in similar situations.
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Perricone Cold Plasma

Perricone Cold Plasma: Overview and Usage Perricone Cold Plasma is manufactured by a beauty and skin care company that was founded by Dr. Nicholas Perricone, a dermatologist who specializes in aging skin. This product contains a variety of ingredients like Palmitoyl Tetrapeptide 3, Dimethicone, and Acetyl Hexapeptide 8, and is designed to reverse the signs of aging, reduce blotchiness, increase skin tone, and improve the texture of the skin. In addition to the Perricone Cold Plasma treatment, the company also carries products for sensitive skin, those that fight dry skin, and enlarged pores. The manufacturer, Perricone MD, was launched in 1997, and the products created by the company focus on reducing inflammation as a strategy to kin treatment. Perricone Cold Plasma and other skin care products manufactured under the brand are now available at the company website, at online skin care retailers, and at select U.S. spas.

About Perricone Cold Plasma

Perricone Cold Plasma contains both chemical and natural ingredients such as proprietary neuropeptides that are designed to tone the skin and erase the appearance of fine lines and wrinkles. Other ingredients include tocotrienols, which is a high-grade form of vitamin E, and can act as a natural preservative. This Perricone Cold Plasma ingredient also provides the formula with an emollient that is to lock in moisture so that the product can continue to treat the skin for a longer period of time. Perricone Cold Plasma also contains glycerin, glycol, and palm oil, and avoids the inclusion of fragrance. However, if you read the Perricone Cold Plasma reviews on the company website, you will note that an unpleasant odor is sometimes associated with the product when it’s first applied – making it a better choice for evening usage.

Perricone MD Neuropeptide Facial Cream Review

Perricone MD Neuropeptide Facial Cream is a daytime wrinkle cream that is said to sculpt and firm skin's appearance immediately after application, as well as dramatically improve the appearance of severe loss of skin elasticity and volume. Neuropeptides are small protein-like molecules used by neurons to communicate with each other. The main peptide in the Perricone MD Neuropeptide Facial Cream is acetyl tetrapeptide-9. Acetyl tetrapeptide-9 stimulates the synthesis of the proteins lumican and collagen I, which in turn increases the quality of dermal extracellular matrix (ECM). The ECM is a complex structural scaffold that supports and surrounds the cells in the skin. Destruction and loss of the ECM is a major cause of skin aging. Therefore, by increasing the quality of the ECM, acetyl tetrapeptide-9 promotes a more firm, youthful complexion.

Another key ingredient in the Perricone MD Neuropeptide Facial Cream is dimethyl MEA (DMAE). DMAE is an analog of the B vitamin choline and is a precursor of acetylcholine, a neurotransmitter. DMAE works by helping the underlying facial muscles to contract, thus tightening the skin and increasing skin firmness. Lastly, Perricone MD Neuropeptide Facial Cream contains the amino acid tyrosine. Amino acids assist the skin in making important proteins, such as collagen and elastin. Tyrosine also improves skin hydration because amino acids work together with aquaporins (the body’s water transport system) to move moisture throughout skin. Overall, Perricone MD Neuropeptide Facial Cream provides your skin with the important building blocks it needs to restore firmness, elasticity, and volume.
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Perricone Blue Plasma

Perricone Blue Plasma: Product Overview and Information Perricone MD Blue Plasma is a skin exfoliant formulated to brighten the skin and even out skin tone by lifting away dead skin cells. Perricone MD which was founded by Dr. Nicholas Perricone in 1997, also markets other skin care products, such as; anti-aging serums and creams, moisturizers, skin cleansers, and products to repair sun-damaged skin. The company claims that Perricone MD Blue Plasma attacks only dead skin cells and lifts them away without damaging or irritating healthy skin, which leaves it looking bright and refreshed. Perricone MD Blue Plasma contains a number of natural and synthetic ingredients and is suitable for both men and women over the age of eighteen.

About Perricone MD Blue Plasma

Perricone MD Blue Plasma is a thin liquid serum that is blue in color, which gives the product its name. The coloration of the product comes from a variety of ingredients, such as copper and synthetic dyes. The serum is packaged in a clear bottle that is topped with a dropper that dispenses the serum. Because this bottle is not opaque and the serum's ingredients may be damaged by direct sunlight, you should always store your Perricone MD Blue Plasma in a cool, dry place that is not exposed to sunlight.
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Perricone Sub D

Perricone Sub D is a cream that was designed to slow down the effects of aging that occur around the jawline, neck and chin. The company, Perricone MD, which was founded by Dr. Nicholas Perricone, who created this cream to help the sagging skin in these areas appear firmer, tighter and more radiant. Now, the cream is thought to help improve the user’s appearance in two ways… Firstly, Perricone Sub D tightens the loose skin and may help to eliminate the appearance of a double chin that is often caused by sagging skin due to loss of collagen and the gradual effects of gravity. This is important, because many people think that a double chin is simply the effect of excess fact, and few focus on treating the skin in this sensitive area to fortify it against the constant pulling of gravity and facial muscles. Secondly, Perricone Sub D can help eliminate the lines and wrinkles that appear on the neck and helps to improve the overall texture of the skin.
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  • General 05.11.20 Reply

    DMAE creams contain an ingredient called DMAE, which stands for Dimethylaminoethanol. This ingredient is a nutrient that occurs naturally in our brain, in small amounts, and facilitates the synthesis of acetylcholine. Acetylcholine is a neurotransmitter that helps in establishing communication between nerves and muscles, and also in carrying messages between brain cells. Acetylcholine works by sending messages to the muscles and stimulates their contraction. Because of this property, a DMAE cream has been used by some patients to address sagging skin. The active ingredient helps stimulate the production of acetylcholine, and that enhances the skin tone by firming and tightening its appearance from beneath the skin.

    Another way that DMAE helps the skin is by reducing the accumulation of lipofuscin deposits inside cells. Lipofuscin is a skin pigment that can create discolorations. It has a brownish color and is a result of molecular waste when fatty acids are not metabolized properly by the body. This pigment oftentimes shows up in the form of liver spots or age spots, especially in people who are at a more mature stage in their life. DMAE creams also tend to have anti-inflammatory properties and can help reduce free radicals in the body.

    DMAE is commonly used in different skin products partially as a pH buffer. It is often recommended to take vitamins, such as vitamin C and B, when using a DMAE cream in order to maximize the anti-aging benefits of the cream. DMAE creams are often combined with treatments containing other anti-aging ingredients such as alpha lipoic acid and anti-oxidants. It is important to check that the DMAE cream is free of irritants like parabens and synthetic fragrances.

  • Lori Mohs 01.18.20 Reply

    For my 35th birthday, I bought myself the book, The Wrinkle Cure, by Dr. Perricone. Over the years, I have built up my cleansing, moisturizing, and anti aging regime to include his products. Along with that, I do eat healthy meals. I stay away from red meats, and processed foods, and stay out of the sun. I take omega 3 fish oil every day, along with COQ10, and Vitamin C. I am sure to workout every day by doing cardio exercises and 3 days a week of strength training. I just turned 53 and can definitely say that I look and feel younger than my age and I am blessed with very few wrinkles, thanks to this book. It was the best birthday gift I have ever gave myself🌸

  • Mary Enloe 10.08.19 Reply

    I do NOT believe the latest comments – too suspicious with similar dates and similar comments. Someone is trying to discredit a really good product.

  • Scratching Diva 05.07.19 Reply

    I can confirm that I am itching all over and I have a rash on my neck from using Cold Plasma. I have been itching all day and night since I bought a this a week ago. I’m glad others have spoken up about this as I couldn’t figure out what it was but decided to Google itchy and MD Perricone and this page came up. Thank you for the reviews. I will stop using it.

  • Katherine Shapiro 04.21.19 Reply

    I have very sensitive skin and have had no adverse reaction from The Dr Perricone products. In fact my skin looks healthy and glowing and my neck has shown noticeable improvement . I took off one star for the price and slightly unpleasant scent of the sub d neck plasma.

  • Jan Hanahan 04.15.19 Reply

    I’ve had the same issues: skin under my eyes is red, swollen, puffy, itchy, scaly and it burns! I thought initially it was due to some oral surgery I have but now confirmed it’s the Perricone Eyelid Lift Serum.

  • Susan Green 01.19.19 Reply

    I feel that i must warn people about this product. It burned my skin and on my second test to ensure it was the products resulting in itching and burning i contacted the company. The company did not seem interested and refused to refund my money. I saved the products in case there was a class action. I believe this company needs to realize not everyone should use this. It was agony for several weeks

  • Lulu 01.18.19 Reply

    I used the no foundation foundation serum. I experienced a terrible face burn and a scaly face. My eyes puffed up. It is horrible. Initially it was itchy, when I woke up my face was all red and dry feeling, scaly. I called the company and they were useless. The product was refunded by the company I purchased it from. Very fortunate. I used the regular no foundation with no problems for three years. The serum must be stronger. I would not recommend the serum.

  • Nataliia 11.19.18 Reply

    I rarely write reviews … I am not an allergic usually … but I am allergic to these products! itching, rashes, and scaly, scaly skin … It’s a nightmare! I can not leave the house! I would sue the company! I am on the verge and in shock !!! I bought as many as 3 products of this company, what a terrible regret!

  • Celestine Optland 10.25.18 Reply

    I love the perricone products. I have very sensitive skin and this product has never let me down. The eye creams are truly my favs. Give it a try, give it a chance.

  • Luba 06.03.18 Reply

    Cold plasma Sub-D equals Rash from hell. After just two uses, I developed a burning, itching rash on my neck, which lasted over a week.
    Scratching all night, almost went to a doctor. It felt like a really bad burn, nothing I put on it helped. After a month I tried again just a small
    Patch on my neck, just to make sure, same exact thing happened. I do not have a sensitive skin at all. There should be a label with worning.
    The manufacturer must know about this, there is way too many people complaining. I am 56, it never happened with any other cosmetics.
    Thanks for all your reviews, glad I am not the only one.

  • Chad 02.26.18 Reply

    First off I am a doctor and this is a real review. I heard about the Perricone Cold Plasma D products and wanted to give them a try. This stuff is nothing more than an expensive moisturizing system. Guys, you need a serum in addition to moisturizers. The Perricone MD products I used did not absorb easily into the facial skin, rather the products just sat on the surface of the skin. No, I am not using too much and I exfoliate daily. Don’t waste your money. I am not one to give other product endorsements, but I have had much better luck and results with the skin care products from Life Cell. For guys that travel often…like me…Life Cell is one tube — NOT five jars. Plus, you see results fast. With the Perricone MD products, I had to really rub and pull on my skin to get the products to absorb. That really defeats the purpose. Poor absorption + excessive pulling on the skin = potential for exacerbation of the appearance of “wrinkling skin”.

  • Joanne Johnson 02.25.18 Reply

    Cold Plasma: Is this product a joke. I’ve used a lot of amazing products in my life but nothing like this. I’m not sure if your noses work but it stinks. It absolutely stinks like dead fish/ castor oil. My husband won’t come near me. I can’t even stand the smell of myself. Even if in looked 30 years younger I wouldn’t use it again. Thanks for allowing me this forum to tell the truth.

  • Bruce Barnburner 02.20.18 Reply

    As a long time avid believer in Perricone MD Product Line, this mainly because it shows results and works.! It Seems to be Serious Science Based Skincare, seemingly innocuous and some Holistic Verbage thrown in….and as so, you would have to be serious about putting out the big $$$ in the long run to get the results you need. We have big faith , and believe in the Science, there fore it rolls along…But amongst all the superficial claims and what All Those Glowing Reviews proclaim, there is a dirty little secret buried within the science of Perricone MD that should be revealed. Pls read, this is important for all us fans of our dear Doctor P.

    Myself… Regarding the following disclosures. I am quite shocked and feel quite betrayed… As This is perhaps so wide spread throughout the Whole of the Cosmoceutical Industry ….. It is a wake up call….Pls read on:

  • Paul 02.05.18 Reply

    I am a 40 year old guy who was looking for a quality skin cream so that I could stop wasting time and money on stuff that doesnt work. Perricone is actually amazing and finally a cream that I can actually see a difference with. Even if it looks like it costs more, it doesnt, compare that to a cheap bottle of moisturpriser from your local supermarket that last a week, this stuff lasts forever so is not only far better quality, but also works out to be the same price or cheaper. I won’t be moving from Perricone now that I’ve found how good it is!

  • Lucinda Walker 01.27.18 Reply

    I developed an itchy rash from two uses of a sample of the high potency anime face lift serum. It’s been a week and it’s still bothering me. I wish I never tried it. It should come with a warning label!

  • Mary 01.11.18 Reply

    I bought items from Perricone, I live in the uk. I have only been using it for 4 days and now my face is burning and there are small red cyst like bumps on my face. It also feels like it is in the muscle of my cheeks. I have stopped using the product immediately and washed it off my face. I have never had any problems with any other products. Fortunately I bought it from a TV show and can get a refund. I am shocked as I have never reacted to anything like this in my life. There is obviously something in it that is not agreeing with some customers. I have always taken care of my skin and thought I would “upgrade”. Never again. I’m sticking to my usual products and routines from now on.

  • Karen 11.30.17 Reply

    I am 63 years old an have been using Perricone products for 20 years and am quite happy with it. I no longer have forehead wrinkles, or the laugh lines by my eyes. I also don’t have the deep folds by my mouth. I have never had a reaction to the products. Most people think I am much younger than I am due to the lack of wrinkles on my face and neck. I am quite happy with the products and will continue to use them. I still have a small bit of sun damage due to getting a deep tan every summer in my younger days but even that is far less apparent.

  • Kristin 09.24.17 Reply

    I wish I had read all these reviews before purchasing the products. I purchased and used (twice) the High Potency eye cream and had the most horrific allergic reaction that kept me out of work for 5 days. My eyes were severely swollen, itchy, red, constantly watering/tearing, and matted shut when I would wake up. I thought I had pinkeye, but then I wasn’t showing the same symptoms. After three doctor appointments and 4 trips to the pharmacy, I was put on a topical steroid, oral steroid and steroid eye cream. The amount of money that I spent on doctors appointments and trips to the pharmacy far supersedes what I paid for this eye cream. I did email the company and they sent me a return label that same day. But NO ONE should put themselves at risk with this stuff. This has been one of the worst weeks of my life.

  • Leigh Poole 06.11.17 Reply

    I have been using dr. Perricone no makeup makeup serum for around two years now about two weeks ago I had to purchase my Foundation as well as my bronzer. Something has gone wrong. I have never had a negative reaction to this product until this last batch that I purchased. After about an hour after applying my skin begin to itch I washed my face and through the next few hours my face continue to itch and burn now my face appears to have a horrible sunburn I contacted a doctor Perricone representative and she assured me that dr. Perricone had not changed his product in any way and that this is the first she has heard of any reaction to any of his products something is going on my face is burning and itching it was suggested to use hydrocortisone cream but it is not helping I don’t think I will be using this product ever again

  • Ida Strickland 05.18.17 Reply

    Like all the women in the world we are looking for the miracle cream. We all want to look younger. I believe when you hear about a product and they use characters like actors and I cannot believe they stand by this product. They don’t put the ingredients in their products. When I first saw the commercial on tv and of course we are suckers to these beauty products. After trying the product I think a week I starting breaking out with itchy and red scaly rash puffy face it last month’s before it clear my face was a solid red and I was so embarrass to present myself to the public. The eye cream called the blue plasma for eyes. The results were horribly horrific. I recommend to research more about this products. I cannot believe that they get away by selling of this products. I am not the only one with this results. I recommend protect your skin do not buy the product. I feel I am going to research what can I do to find out more about their company and what can I do to help people like myself who has taking advantage of women wanted to look younger and not knowing what your putting in your skin. My products do not have the ingredients. I want to take my product to have it tested.

  • Jen 04.29.17 Reply

    Absolutely LOVE the products I have been using!!!! I used another “Dr. G*&^%” and never saw this amount of improvement. I used the other product for one year, used Dr. Perricone for 2 months. My family and friends still think I went under the needle. Lol. I hope to get them hooked!! Thank you
    Much Care
    Jennifer

  • Ray 04.20.17 Reply

    I just decided to check my billing statement on-line and there was a charge of $49.95 from Perricone. I called their 800 number and spoke with a call center person (with an Indian (?) accent) who explained that this was for my final balance of my order. I only ordered once and it was from Sephora. The call center person said, per my account, my next shipment would be in May and I told him I do not want any more product. He asked me why and I told him I rarely use the product. He said he would delay the next shipment. I told him I want to close my account (which I had no idea I even had an account). He was very pleasant and not pushy at all but I smell a rat with this company. Maybe this review has nothing to do with the product itself but I do not trust this company and now I am leery of Sephora

  • Yohanna 04.06.17 Reply

    Was excited to try Sub-D from Perricone but after trying for awhile it didn’t work. I called Perricone and told them to cancel and returned the product. It took a very long time to receive the refund and finally did it but the refund was less than originally paid for. However, I received another package from them and they charged me again and they said this was the auto refill of which I said I did not want and have already cancelled it. They asked to return again and now I have to wait for a long time before receiving refund. I am super upset with Perricone and this company is not to be trusted. Be very careful with their marketing gimmicks and closely monitor your credit card statement.

  • Lynn 04.04.17 Reply

    I was really excited to try the Dr. Perricone products when I saw them on GMA steals & deals. I had my eye on the product line at Sephora so I was thrilled to be able to get my hands on them at half off and without having to enroll in the auto program offered by Perricone. Unfortunately, I had a severe reaction to the Cold Plasma eye cream and a mild one to the Cold Plasma face/neck cream. After two uses I had burns under both eyes. One of my eyes actually looks like I was hit in the eye the burn is so dark. I think this product is “use at your own risk” after reading all the posts on burns. I have used other products that are considered somewhat harsh on the skin with no negative effects (Obagi). I did experience good customer service when I called to get the refund process started. The woman was friendly & there was no run around. It’s unfortunate this happened and I am now hesitant to try any other products from Dr. Perricone. I definitely think a warning on the label is needed. I also hope this burn goes away in a timely fashion. It’s very enflamed and uncomfortable. The rash on my chest from the face/neck cream is already starting to heal and wasn’t as severe, but again, not ideal and won’t be using that product anymore going forward. Again, use the eye cream at your own risk and I wouldn’t recommend it. My burns came on fast and are not mild. Even neosporin is aggitating the burn. Much more significant than a “sun burn” and more along the lines of a chemical burn.

  • Rachel Casto 03.14.17 Reply

    Anyone that says anything good about this product is either getting paid to say it or is full of crap. This products does absolutely nothing, and as far as the return policy, you have to fight with the operator

  • Marcy 03.06.17 Reply

    Well after hearing good and bad reviews of this products i will give them the benefit of the doubt. There can be lots of factors that the product is not working for every one, maybe they neglect their skin for a long time and now they want miracles over night, or maybe using to much product and saturating the skin, maybe the products they used after like make ups that is making a bad chemical combination reaction to the skin. I know they are pricey but sometimes we spent more money neglecting our sink and body with other bad habits. Im 37 and i have very very sensitive skin and dark circles, i have used the products for few days and seems to work fine, but we never know after a while, but other experiences i had with other facial products gave a rash or itching immediately and i could tell right there in then that the product wasn’t for me. So i want to belive in Perricone and give it a chance. I will write another review after using the product enough time, and time will give me the reason to stay or quit.

  • Trin 02.15.17 Reply

    I ordered this product after viewing a commercial. I started to use the products with no issue. 3 weeks later I developed a rash on my face and neck. I visited my Doctor and was given cortisone injection and put on medication. The itching was horrific, I would wake up at night and scratch to no end. It felt like my skin was on fire. I was unable to go out for a week as my rash was bright red and extremely uncomfortable. I decided to try the product again 3 months later ( I was sent an automatic shipment). After just one day the rash and itching started. I sent a letter to the company informing them of my rash, and requested them to stop sending the product. They did not respond and continue to send the product bill me. It obvious they do not take the time to read letters and care about their clients. Disappointed

  • Louise 02.07.17 Reply

    I’ve been using these products (Perricone MD Neuropeptide Night Cream, Hypoallergenic Firming Eye Cream, Cold Plasma Sub-D, Face Finishing Moisturiser and No Foundation Foundation) for about two weeks. Initially, I was delighted noticing a real improvement in the texture and appearance of my skin. A couple of days ago I felt my eyes feeling scratchy and very itchy in the corners and yesterday, a red, bumpy and itchy rash on my neck. Tonight, my eyes are burning and streaming. QVC are happy for me to return products and receive a refund which is brilliant of them but really worried that I may have caused some real damage. Really unhappy ?

  • Antoinette in Queens, NY 01.16.17 Reply

    Dr, Perricone products in my experience and opinion are not only bad for your skins causing severe skin damage and permanent discoloration it may also be hazardous to your health. I used his product for only a few days and it appears it caused a lifetime of damage. I have always had beautiful near flawless skin and I only decided to use the products after seeing a very convincing Infomercial. I thought since I was in my 50’s I might be time to get started on preventive care before the wrinkles came. Honestly I had no wrinkles and have very little two years after the severe skin damage I experienced from Dr. Perricone product use. My face was severely burned, dry and it looked like I was cut – that is how deep and severe the wrinkles that I never had but after use of this product, The itching and redness were severe and lasted for months. It cause me great embarrassment and humiliation. I became depressed and just wanted to hide my face. The product had also lightened my already light skin in areas and I was told the damage could not be revered. This is a horrible product that not only didn’t work but caused severe and permanent damage. I am afraid everyday. I have headaches and I am not sure if the product entered my body and will later cause other issues.

  • Vicky S. 10.13.16 Reply

    I have been using Perricone MD for over a year now and it does work wonders for me. At 45 years old I started seeing the signs of aging in my face: discoloration, wrinkles on my forehead, and dryness. I started using Dr. Perricone’s products and I have seen a huge improvement. I use: Neuropeptide Facial Cream, Acyl-Glutathione Eyelid Serum, Neuropeptide Necolletage and Firming Pads (this is my toner). I got the first 4 products mentioned as a skin care set through QVC and it was affordable. These along with the Nutritive and Sensitive Cleansers keeps my skin young and healthy. No more issues. My skin looks radiant, wonderful. Got many compliments at work, at the gym, everywhere.

  • Barbara Ewalt 09.18.16 Reply

    I ordered a trial kit and thought that was that. But then all of a sudden more products were coming and my credit card was charged. I never was told about this. I had to cancel my credit card to avoid more billing. On top of that the products made my face very red and rough. I finally figured out the products were the cause. My eyes were puffy with a red itchy rash. I have used Retin A and have never had the amount of redness and eye discomfort I have had with this product. Besides the poor customer service the product didn’t work for me either. it will take awhile for my skin to return to its prior state.

  • Editor 09.07.16 Reply

    We’re sorry to see you didn’t see any results. Please take a look at Advanced Dermatology. It is our #1 recommendation on the site. Read the review but don’t expect fancy packaging or pleasant fragrances. These are dermatological skin care products. Not luxury products.

  • Hilda Conti 08.19.16 Reply

    I have used this products and end up in the dr office just like you – burning swelling and my eyelids failed down – very painful
    I am under Drs care now and I hope this is a temporary damage !!!
    Terrible experience !!!

  • Ruk claro 08.16.16 Reply

    Why is it hard to return the items ? Please help . I developed rash all over my face and neck after two days of using it !

  • Lori Zimmerman 04.10.16 Reply

    I, too, develop a rash after using the product for a couple of months. I stopped using everything and slowly introduced products one at a time. I opened a new jar of the neck cream and applied it. I had what felt like second degree sun burn with bumps on my next area for four days. It was so itchy and burning I couldn’t sleep. I do not have overly sensitive skin either. I was not happy with the product performance before as there are lots just as good and not as expensive. Returning or stopping the automatic billing is not easy. I do NOT recommend and warn others to look else where for skin products. NO STARS!

  • Leigh 02.01.16 Reply

    I had been using Dr. Perricone’s Sub-D for several weeks and developed a red, very itchy rash on my neck. I stopped using it and used OTC cortizone creme for a couple of days, then the rash subsided a good deal. I tried the Sub-D once more and…the rash returned. There may be some herbs in it that cause allergy, but I think I’m going to stop all his products, just to be safe.

  • Cindy 01.06.16 Reply

    Stay away from this Company. In addition to getting a very hot itchy rash on my neck and eyes (I do not have sensitive skin), I cancelled my order. However, for the last 8 months I’ve been battling to get them to stop sending their product and stop charging me. Finally the product stopped but not the billing! Very bad customer servie ~ you’ve been warned!

  • Cindy 01.06.16 Reply

    Dear Coral,
    I’ve just been on the phone off and on (between my bank and Perricone MD) for the last 2 hours. They are impossible! However, I will share with you the fax number they gave me to send my bank statment as proof they charged but have not credited back what they owe me. The number is 828 684 1730. I asked for proof from them that they paid and of course they could not. Likely because they hadn’t done it, hoped I forget about it. Good luck!

  • Phyllis O'Neal O'Brien 11.07.15 Reply

    I would actually give these products a minus star if I could as I, too, developed the same skin irritation as others. Not only did my neck develop an itchy rash, but my eyes became puffy and my entire face was a dry, flaky mess! It took me a while to figure out the cause, because I had been using the Perricone products for almost 8 months (proof that a new shipment after three months is NOT needed). After eliminating all products I was using and bringing things back one at a time, there’s no doubt the Perricone products were the cause of my troubles. I also did not like their marketing practices. After receiving the initial package of products for the “three month trial,” I could not find any written information regarding what I had signed up for. I called immediately, asked again for the terms, and came to the conclusion that they purposely don’t send written documentation of the terms. I expressed my dissatisfaction with their sales practices and discontinued the recurring shipments. So glad I did!

  • peg 09.30.15 Reply

    I bought the sub d plasma neck cream and developed an itchy rash from use. it took a week to get my skin back to normal. I decided to try again months later and same thing happened. I used product in late fall, at night before bed and cleansed skin in morning to remove before going outside thinking sunlight might be causing sensitivity. it is very expensive and I do not recommend it to anyone.

  • Tanya 09.21.15 Reply

    I love Perricone products. I have been using them for the past 12 years. It is expensive, but it works for me. I started using products, when I was 28, because, I had Rosesea and antibiotics did not work, but Perricone products did work. I’m 40 years old now. I love my skin and people say I do not age. People say, I look in the early 30th. I do have to budget which products I buy. I do have sensitive skin and skin allergies, so I almost always use the same products that I used 12 years ago and they are not the most expensive ones. I never returned products that I ordered, and I never did automatic renewals, so I never had to deal with customer service. I usually wait for promotions on Perricone website. I switch to other brands, but always came back to my favorite Perricone, because my skin loves it. Over the years, I used Perricone hypoallergenic line. I like it. However, my favorites are: face finishing moisturizer, eye serum, citrus wash, and vitamin c ester products. I’m planning on using Perricone products as long as I can afford them.

  • Annie 04.28.15 Reply

    I just had a very similar thing happen. I bought Perricone High Potency Eye Treatment and after two days of using it my eyes are swollen with angry red marks and very itchy. The area also feels very dry and slightly grainy. I am upset with myself for paying $118 for this product at Sephora and tossing the receipt when I got home. I’m pretty sure I can’t take it back anymore.

  • Nancy Bowman 04.05.15 Reply

    Ordered the trial kit and was told no subsequent shipment would arrive, UNTRUE, 30 days later, my charge card was billed for another shipment. The first shipment arrived with no instructions for use, that’s how rushed they are to send out the stuff. I called this morning pretending to order and was told no future shipments would be sent,. HA! I have returned all products but Perricone MD keeps sending me a bill. Even the collection agency they use, apologized for any inconvenience upon hearing from my attorney.Perricone answered my one blog because it was a public site but haven’t responded to my later comments. Should have remembered my rotation in dermatology, creams on the outside don’t work. Beautiful skin is from the inside. I would guess most of the positive comments are from Perricone, itself.

  • mindy paul 03.31.15 Reply

    I also am suffering from a red, hot, itchy rash on my neck. I don’t know what to do about it and my dr. is not calling me back. I put an ice pack on my neck this morning and am using anti-itch cream. It seems a little less red after a day. This was a very expensive rash!

  • Lynne 03.30.15 Reply

    I had been using the no Foundation Foundation along with the bronzer and blush. It was fine for a couple months, then I stopped due to foot surgery and not going out of the house. When I used the products again, I developed a rash with swelling and itching. Had to take a Benedryl to get the swelling and itch to stop. I waited till that cleared up and tried it again. Worse reaction that time. After more Benedryl and Shea butter to clear what looked like a chemical burn on my face I will not be using any Perricone products again.

  • Lynn 03.19.15 Reply

    Also used Plasma Sub D for my neck and developed a red itchy rash. I stopped using it and the rash cleared up. After a few weeks I tried using it again because I was not certain of the cause, and once again the rash appeared. Wound up throwing the jar away.

  • Ramona 03.12.15 Reply

    After two months of using these products my face has developed an itchy red rash. Will have to discontinue and never purchase again.

  • wanda 02.17.15 Reply

    I tried the Cold Plasma Sub D the blue plasma eye and face lift.
    I used 1 time the next day my entire face and neck burnt, the next day my face was so swollen I could not go to work.
    They did give my money back right away but that did not cover the Doctors bill I had to pay. I am on day three of my recovery face red and eyes still swollen, now skin is starting to crack it hurts,
    I just hope there is no lasting scars.

  • Gerry 01.10.15 Reply

    I bought the today special value. I was very excited to try the product. One girl I worked with said gerry you will never get ride if your lines on your face and neck. I guess it was about four days into using the product when some one asked me was I getting Botox. I started noticing that my cheek bones and my eye lids where swelling. I starting using smaller amounts. After the 5 day I noticed my neck had a red rash all over. Called the company they suggested me to stop using the product for a couple of days. After that try one at a time to see what one I had a reaction to. So that is where I am at now. We will see how it goes I guess.

  • Coral 01.10.15 Reply

    I am very upset that I can not talk to a customer person if I am not placing an order. They are fast to answer if you press 1 to place an order but if it is for anything other than placing an order a recording comes on and you are not able to speak to someone. The service sucks…. I need to speak to someone other than the order desk. They are fast to take your order and your money but tif there is a problem no one will answer the phone and you can’t leave a message. Guess I will go some where else..

  • Maryel 12.18.14 Reply

    I reordered the product, and after a couple of uses noticed the SubD for the neck caused a bright red broken out rash to my chest and jaw line. It was itchy and so irritated I had to cover up considerably when leaving the house! I stopped immediately and it took a few DAYS for the severe scarey rash and red flush to go down. I can still see a bit of it “under the skin,” and have been just trying to wash gently and apply skin soothing rash ointment which seems to be working. this smelly product hopefully has not left any permanent damage to my skin.

  • paula 11.08.14 Reply

    Andrea, i also used the neck cream and developed a horrible rash, with bumps and itched horribly. Skin is bright red. Any suggestions on what to do?

  • Donna 10.20.14 Reply

    Within a week after first using the product, my husband thanked me for using the product, he was happy with the results on my neck…

  • Lauri 09.05.14 Reply

    I have to say that, when used in the recommended combinations, Dr. Perricone products really do what they say they’ll do. I’ve used the acne/pore reducing regimen, as well as an anti-anging regimen. My issue with Dr. Perricone is 2-fold. First of all, the products are extremely expensive. My second issue is with customer service. I signed up for the auto-renewal to save a bit of money, but as another reviewer mentioned, it is very clear that this company’s customer service M.O. is to trap you into spending money and then being very hard to reach to deal with problems. You cannot manage your auto-renewals online (say to skip a delivery or change the frequency), you have to call the company…which you inevitably are too busy to do and then wind up with a bunch of extra product. All of this being said, the products work extremely well and will achieve results in just a manner of weeks.

  • rjfelix 08.17.14 Reply

    I tried the Perricone plasma but found it left my skin too dry. I called and cancelled future orders and I was so surprised and grateful that it was cancelled and the money was redeposited in my account. This is one honest and reputable company is my experience.

  • Linda 07.31.14 Reply

    I have had a problem with a very red itchy rash on my neck and the hand I used to apply it, after using Sub D cold plasma. After the first bout I stopped, then tried it again and the same thing occurred. I do not have sensitive skin and have had no previous skin problems.

  • Linda 07.31.14 Reply

    I used Sub D Plasma on my neck for several months, once, occasionally twice a day. I developed a very itchy, red rash on my neck and on the hand I use to apply it.

  • Tommy 07.30.14 Reply

    Pat,

    Have you ever received your refund? I am having the same issue with something that my wife purchased and the told her 4-6 weeks for the credit to show but I don’t believe it will happen.

  • Karen 06.04.14 Reply

    I have just ordered my first shipment, and am looking forward to trying Dr. Perricone’s products. I was able to get in on a great deal that was being offered, otherwise I would have said no, to the price. I will post another review once I have my products!

  • Lurline 06.04.14 Reply

    The Amine Face Lift did not work for me ,it makes my complexion dark,and the
    Sub-D after three months use I did not see much improvement. Besides the products are too expensive.

  • Barbara 05.23.14 Reply

    I asked for a TRIAL SHIPMENT from this company. They sent it to me then sent another shipment and charged my credit card $104. I had to pay to ship it back and I’m jumping through hoops to get my money back.

    They will not give anyone a phone number for their billing department and require 4 to 6 weeks to process a return!

    I would not encourage anyone to deal with this company!

  • Andrea 05.17.14 Reply

    I was very curious about the Perricone Sub-D cream for the neck and finally succumbed to purchasing when I received a department store gift certificate that defrayed part of the ridiculously high cost. Just like another person’s comment above, I used the product with no problem (and no results) for about a month when developed a very itchy rash that was difficult to clear up. When it finally healed, I waited a couple of weeks and tried the cream one more time, hoping it was not the cause. It was. I won’t use this stuff again.

  • samin 04.27.14 Reply

    I ordered the neck cream kit to try his products. I did not see any changes and the product was smelly.

    The bigger problem came later when I received another package that I never ordered. I called them and they tolled me I can return it. Who has the time to go to post office to return it. Anyway I have filled a dispute….let see. If you want to buy it, buy it from QVC.com only. I never buy his products anymore.

  • Diana 04.27.14 Reply

    I just started using the cold plasma eye cream, I am a 51 yr young woman with very dry skin and dark circles under my eyes, when I put on concealer it does not blend well due to dryness. I just started using this cream twice daily and so far it feels better, but I am still not sold that it works. I will try for a few months and return with a verdict.

  • Susan Trear 04.08.14 Reply

    I will take responsibility for not following their pricing when I first purchased, however: Ordered first “kit” in January 2014, a “3-mo supply” of items, for $99.95. Then was billed additional $79.95 in February and again in March. So, a 3-mo supply (one kit) will actually cost you around $260.00. Too much for a retired person I’m afraid. No complaints about the products; they seem pretty good, but too pricey. There are other effective product lines I believe.

  • Pat 04.03.14 Reply

    This product not only did not provide the skin care results it touted – there were repeated charges over months that are still unresolved for over $1400.00 for product I never reveived nor wanted. Perricone was unwilling to stand by their products, accept returns of product and issue the appropriate credits.
    Not a reputable company – wouldn’t recommend anyone purchase anything from them.

  • RH 02.22.14 Reply

    I used the Sub-D neck area cream and liked it at first, but after about a month I had an adverse reaction to it. My neck turned red from a very itchy rash which lasted 3days after I stopped using it. The extreme night cream hasn’t caused me any problems, nor has the daytime facelift cream, and they both seem to keep my skin soft. My favorite product is the No Foundation Foundation – now that is awesome. My overall opinion is that his products are good, but not any better than Murad products.

  • Stella 11.07.13 Reply

    Okay, after reading this review I bought both the Targeted and Corrective Skin Care Regiments to try. So I am using all o the following products:
    Targed Skin Care regimen with Cold Plasma, High Potency Eveniong Repair and Advanced Eye Area Therapy. I also added Ntritive Cleanser., Formula 15 and Face Finishing Moisturizer.
    Perricone skin care products are expensive but I have read good things about them.

  • Sabrina 10.24.13 Reply

    Great products. I trust Doctor Perricone MD with my skin care needs. I am not sure if it just me or everybody has the same experience with Perricone skin care products. The Cold Plasma Eye Cream is out of this world. Great product.

  • Peter 09.08.13 Reply

    I have been using Perricone skin care product for several years and people keep telling me I have beautiful skin. Yes the products are expansive but they are well worth it because they use higher grade ingredients that actually work.

  • Amy 07.23.13 Reply

    Perricone Cold Plasma skin care for a week, I dont feel any dryness on my face anymore. Seriously. Great product.

  • Perricone Review 07.18.13 Reply

    I am so glad to see this review on Perricone skin care. I’m a big fan of Dr Perricone anti aging products I agree with the review above about cold plasma and it is definitely the best wrinkle cream you can buy – if you can afford it. I get tons of positive comments on my skin so I definitely know how to take care of it and which products to use.

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