One Skin Reviews: A Review of The 5 Best One Skin Products



What unfolds when four longevity scientists discover the secret to reverse the aging of your skin? Enter OneSkin, a pioneering range of skin health products driven by longevity science to address the root causes of aging. 


1Carrot & Stick Review
-One Skin

In contrast to most “science-backed” skincare companies that rely on external labs, OneSkin sets itself apart with their team of scientists who personally oversee the entire research and development process in-house. The result? Science as the top priority, followed by product development, all backed by validated data. 

In this review, we’ll give you all the details on One Skin products, including the key ingredients and what you need to know about the brand’s proprietary OS-01 peptide. We’ll also share some One Skin reviews so that you can get an idea of what customers really think of these products. 

What Are The Top 5 Best One Skin Products?

The current One Skin lineup consists of five products, and below we’ll give you a breakdown of each one. 

One Skin PREP Facial Cleanser

Start your routine with the One Skin PREP Facial Cleanser, a mild daily facial cleanser designed to effectively eliminate impurities, light makeup, and sunscreen while preserving the skin’s natural barrier.

Unlike most cleansers that contain detergents and harsh chemicals, this One Skin cleanser is formulated with gentle enzymes to help remove impurities without irritating the skin. This paves the way for optimal moisture retention and a healthy complexion, making it suitable for all skin types and ensuring skin is ready to fully absorb the benefits of your skincare routine.

One Skin OS-01 FACE Topical Supplement

Backed by scientific evidence, OS-01 FACE is a daily moisturizer that’s formulated to combat the underlying factors of skin aging, resulting in a healthier and more youthful appearance. The formula features the brand’s proprietary OS-01 peptide for areas of your skin that are most exposed to environmental damage, including your face, hands, and neck.

Additionally, the formula includes six active ingredients that complement the OS-01 peptide, such as three sizes of hyaluronic acid, niacinamide, allantoin, oleic pau mulato extract, andiroba oil, and pracaxi oil. 

We love that the formula contains niacinamide, as we consider this to be one of the best skincare ingredients. It’s proven to repair the skin barrier and improve skin moisture, as well as reduce inflammation, blotchiness, hyperpigmentation, acne, and wrinkling. 

We recommend Carrot & Stick The Repair Serum because it combines niacinamide with seven plant-based neuropeptides and soothing, brightening botanicals to promote a youthful glow. 

One Skin OS-01 EYE Topical Supplement

Scientific studies have revealed that the skin surrounding your eyes ages more rapidly than the rest of your skin, marked by heightened levels of cellular senescence (we’ll talk more about what this means in the Key Ingredients section below). That’s why the brand infused the OS-01 EYE Topical Supplement with the highest concentration of their OS-01 peptide to combat the aging process at the molecular level. 

Additionally, the formula includes three active ingredients that support the OS-01 peptide to mitigate visible signs of aging around the eyes. For example, Moringa seed extract serves as a shield for skin cells against environmental pollutants that can accelerate the aging process. Fucus vesiculosus algae extract aids in reducing the visibility of dark circles and fine lines around the eyes, simultaneously improving the skin’s radiance. 

Lastly, biomimetic vegan collagen emulates the human collagen structure and enhances elastin, laminin, collagen, and fibronectin production. Unlike many topical collagen products, it effectively penetrates the skin barrier.

One Skin OS-01 SHIELD Protect + Repair SPF 30+

The One Skin sunscreen, available both tinted and untinted, uses 100% non-nano zinc oxide to provide broad spectrum protection against UV rays. Plus, the OS-01 peptide that’s found in all One Skin products works to reverse UV-induced aging. So just as the name suggests, this sunscreen helps to both protect and repair your skin. 

Ingredients like vitamin C, green tea, acai extract, and tara fruit extract complement OS-01 to neutralize free radicals from UV, blue light, and pollution.

Vitamin C also helps fade dark spots, evens out skin tone, and increases radiance. As if that wasn’t enough, research suggests that when vitamin C is applied to the skin, it significantly reverses aging-related structural changes by influencing collagen and elastin synthesis. 

Our favorite Vitamin C serum is Carrot & Stick The Defence Serum. It contains 3 distinct types of Vitamin C that work together to help fight free radical damage. We recommend using it every morning.

One Skin OS-01 BODY Topical Supplement

Formulated as a daily moisturizer for your body, this hydrating body lotion targets the root cause of skin aging with the brand’s proprietary OS-01 peptide, as well as six supporting key ingredients that support damage repair, enhance the skin barrier, and boost hydration. 

For example, snow mushroom extract, known for being up to 400 times more moisturizing than regular hyaluronic acid, collaborates with glycerin and beet-derived betaine to significantly elevate skin softness and moisture levels. Sulforaphane, a robust antioxidant phytonutrient, boasts antimicrobial and anti-inflammatory attributes. 

Genistein, a potent anti-inflammatory antioxidant, aids in the prevention and reduction of photoaging and dark spots. Lastly, ceramides play a crucial role in supporting the skin’s natural lipid barrier, enhancing moisture retention, and repairing dry and sensitive skin.

What Are The Key Ingredients in One Skin Products?

All One Skin products are powered by OS-01, the first peptide proven to reverse skin’s biological age by preventing the accumulation of senescent cells. But what exactly are “senescent cells” and how do they contribute to aging? 

Over time and with heightened exposure to environmental factors — such as UV light, blue light, and pollution — the DNA of your cells becomes damaged. As this damage accrues, they transition into a state of dysfunction known as senescence, and cellular senescence is a root cause of aging. 

Commonly referred to as “zombie cells,” senescent cells release pro-aging agents, accelerating the aging of nearby healthy cells and inducing their own senescence. As more cells succumb to this “infection,” the body experiences increased inflammation, suppressed immune function, and increased expression of pro-aging genes. 

The greater the number of senescent cells present, the more rapidly your skin undergoes aging. With an increased accumulation of these cells, your skin exhibits an expedited aging process, evident in the form of visible signs such as wrinkles, diminished elasticity and firmness, crepiness, and thinning.

The OS-01 peptide by One Skin enhances the repair of DNA damage in senescent cells, preventing them from releasing pro-aging substances. This effectively halts the spread of senescence and reduces your skin’s biological age at the cellular level. The outcome? Skin that is not only healthier but also maintains a youthful look, feel, and function for longer. 

How Much Do One Skin Products Cost?

One Skin products are mid-range in terms of cost; they aren’t cheap but they are ridiculously expensive. For example, the One Skin OS-01 FACE Topical Supplement costs $120 USD for a one time purchase, and $99 with a subscription. 

Where to Buy One Skin Products?

One Skin Products are sold on the brand’s website, as well as on Amazon. 

What is The One Skin Return Policy?

One Skin offers a 45-day money back guarantee. The policy states, “We are confident you will LOVE our products! So much so that we offer a 45-day money back guarantee on your first order. This means that you can request a refund at any point within 45 days of your first purchase and get your money back with no questions asked. That’s how much we believe in our products!”

Is One Skin Cruelty Free?

Yes, One Skin is cruelty free. 

One Skin Reviews

One Skin reviews  are overall very positive. The product with the most reviews is the One Skin OS-01 FACE Topical Supplement, which has received over 2,000 five-star reviews. 

The positive reviews for the One Skin OS-01 FACE Topical Supplement mention that it’s lightweight, has a nice texture, and does what it says it’s going to do. 

However, there are a handful of negative reviews for the One Skin OS-01 FACE Topical Supplement, which are mostly from customers who did not see the results they were hoping for. 

Our Verdict

Overall, we appreciate how One Skin products stand out amidst the vast array of skincare options available thanks to their OS-01 peptide, which specifically targets the root cause of skin aging.


  • Innovative formulas with OS-01 peptide and supporting key ingredients
  • One Skin is cruelty free
  • Many positive One Skin reviews


  • Some One Skin reviews mention that the products didn’t produce any results, even after months of use

What Are Some Alternatives to One Skin Products?

If you’re looking for skincare products to address the signs of aging, we recommend Carrot & Stick. Carrot & Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin. 



Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds. Read More


The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Read More

No comments yet

Your Review
User Rating: 0.0 (0 votes)

Recommended Articles