Luminesce Review



The luminesce anti-aging skin care line is said to restore youthful vitality and radiance to your skin, reduce the appearance of fine lines and wrinkles and reveal your unique glow. Developed by dermatologists, the formulas in the luminesce line include the proprietary APT-200. So what is APT-200 and how can it help give you more youthful looking skin? Keep reading below to find out!

Brand background

The luminesce line was developed by a global brand of youth enhancement products known as Jeunesse. luminesce is just one of the nine regimens that Jeunesse produces, which are said to work together to keep you looking and feeling young. The skin care products found in the luminesce collection are considered the “rejuvenation” aspect of their nine-part synergistic system.

Key products

There are eight different products that make up the luminesce anti-aging skin care line. Below is a brief description of each of these products.

  • Cellular rejuvenation serum: Applied after cleansing, this serum is said to help minimize the look of fine lines and wrinkles to restore your skin’s youthful radiance. An interesting ingredient in this serum is saccharomyces lysate extract, a yeast compound. The little evidence that can be found for this ingredient suggests that it is a source of beta-glucan, which is a good antioxidant.
  • Flawless skin brightener: This hydrating formula includes ingredients that reduce the appearance hyperpigmentation, refine the look of pores, and brighten skin. Key ingredients in this product include Ascorbyl Glucoside (vitamin C), Niacinamide (vitamin B3), Tranexamic Acid, Achillea Millefolium extract, and Tremella Fuciformis (Silver Ear) Mushroom extract.
  • Hydrashield mask: Jeunesse made the Luminesce HydraShield Mask with biocellulose material rather than paper or hydrogel, because biocellulose masks adhere more snugly to your skin and prevent ingredients from evaporating as quickly. This also helps the HydraShield Mask seal in moisture, giving you up to 24 hours of hydration.
  • Youth restoring cleanser: This cleanser gently removes debris and impurities while exfoliating with alpha and beta hydroxy acids to reveal younger and smoother-looking skin.
  • Daily moisturizing complex: This daytime moisturizer protects your skin from UV rays by using chemical sunscreens, which work by absorbing UV light, then transforming that light energy into some other form of energy, such as heat. It also contains silicones, which give the skin a smooth, silky feel and glycerin, a humectant moisturizer that draws water into the skin.
  • Advanced night repair: Inside this nighttime moisturizer you’ll find antioxidants and hydrating ingredients designed to replenish your skin while you sleep. Some of the antioxidants found in this product include niacinamide (vitamin B3), superoxide dismutase, green tea leaf extract, Tocopheryl Acetate (vitamin E), Retinyl Palmitate (vitamin A), Ubiquinone (CoQ10), and Tetrahexyldecyl Ascorbate (vitamin C).
  • Ultimate lifting masque: After cleansing, this masque can be used to further exfoliate the skin. It is applied for 15 to 20 minutes and then peeled off. Interestingly, this masque does not contain many exfoliating ingredients. It does, however, contain a decent amount of alcohol, so those with dry skin should be cautious if using this product since alcohol can dry out the skin.
  • Essential body renewal: This lotion is designed to be applied all over your body in order to soften and hydrate the skin. It does contain several hydrating ingredients, such as glycerin, niacinamide, squalane, and several fruit extracts.

Key formulation

Developed by Jeunesse’s experienced team of dermatologists, the luminesce products feature the proprietary APT-200, which is the brand’s name for the ingredient “Human Adipose Stromal Cell Conditioned Media Extract”. To break this down for you, adipose is the technical term for fat, therefore, the stromal cells are taken from human fat. Stromal cells have the capability of differentiating into many different types of cells. The conditioned media extract is actually the solution in which the cells are grown. After extracting cells from human adipose tissue thousands of new cells are grown in the lab. Conditioned media is the solution (sugars, amino acids, etc.) that is put in the petri dish in which the cells are grown.

The theory behind using this conditioned media is due to the growth factors and cytokines secreted by the cells as they are being cultured. As we age, these growth factors are reduced, and this is one of the underlying reasons skin has an aged appearance. This commonly shows up as the appearance of fine lines and wrinkles. It is thought that the growth factors and cytokines can work with the natural processes of the skin to support rejuvenation and decrease the appearance of fine lines and wrinkles.

Some people are worried about using products like luminesce because they inaccurately believe that there are actual human cells in these products. It is important to remember that APT-200 is made of the extract from the petri dish in which the cells were grown.

Of note, all of the luminesce products contain fragrance, which is something to be aware of if you have sensitive skin.




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  • Eva szekeres Original review: Jan 29, 2023. Reply

    I am using luminescen skin care ( cleanser, day cream, night cream, serum) for many years and I am very satisfied with the result. I have a dry skin with occasional break out.
    Since I am using this skin care line my skin tone evened out, the break out disappear in one day from the serum and my skin feel nourished. I can highly recommend this product.

  • Linda Servis Original review: Jan 29, 2021. Reply

    NEVER ever buy anything from them. They are crooks. I got what I thought was a $20 product and it ended up costing me $200. Thieves. Never give them your credit card #.

  • Amynah Bhanji Original review: Nov 11, 2019. Reply

    Horrible cream and horrible people. I am disabled and inadvertently clicked to order and then cancelled by email. AND I still got the product AND now they are not picking the phone. Terrible terrible mistake – and they are charging £60 for USELESS product

  • Suhash Original review: May 03, 2019. Reply

    I have used luminesce skin care products such as cleanser, serum, advanced night repair and flawless skin brightner. I used these four products for 2 months .these products are very expensive .i was paid 22000/- . After using these i feel that this is only waste of money.i recommend not to waste your hard earned money in these products

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    Luminesce Cellular Rejuvenation Serum Review

    Jeunesse Skincare is a global beauty and wellness brand that has been creating skincare products, color cosmetics and supplements. Looking at one of their more complex formulas, the Luminesce Cellular Rejuvenation Serum is one of their most intense treatment products that the brand offers active ingredients to target anti-aging, premature aging, skin damage and more. The main actives behind this product include vitamin C, red seaweed and green seaweed extracts. These ingredients are incredibly antioxidant rich, which helps to encourage healthy skin function as well as prevent damage caused by UV rays, pollution and free radicals. Additionally, vitamin C helps to brighten and even out skin tone to deliver a more youthful glow to the skin. In clinical trials, 88% of users saw an improvement in skin’s overall appearance, while 75% saw an improvement in skin smoothness and texture. Additionally, 70% of users saw an improvement in fine lines and wrinkles, and 70% of users saw an improvement in skin’s overall elasticity and firmness. In order to get the best results from this type of product, we recommend applying a thin layer of this product onto freshly cleansed skin two times a day as part of your morning and evening routine, blending until the product has been completely absorbed into the skin.


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