Circadia Skin Care Review



Circadia is a line of skin care products that is centered on the body’s circadian rhythms. The name Circadia is derived from the two Latin words circa dies, meaning “around the day.” The word “circadian” refers to a 24 hour cycle and describes rhythmic changes in our physiology and in our behavior. A recent study revealed the importance of the biological clock in the regeneration of skin. When this system is disrupted it results in premature skin aging, like wrinkles, fine lines, and sagging skin. The Circadia products are formulated to balance this system by defending from environmental insult during the day and stimulating repair mechanisms during sleep.

Circadia’s products utilize paraben-free preservative systems as well as a multitude of cutting edge ingredient technologies for comprehensive treatment of aging skin, pigmentation disorders, acne, and rosacea. The company also produces a clinically evaluated moisturizing pillowcase which is a exclusive all-night skin care treatment accessory. To learn more about the formulations behind Circadia products, keep reading below.



1Carrot & Stick Review
-Circadia Skin Care

Brand background

Circadia was founded by Dr. Peter T. Pugliese, MD, who has spent more than 40 years dedicated to the science of skin and aging. Dr. Pugliese believes that the integration of medicine, science, and nature is the basis for creating functional products to enhance skin health and longevity. Only ingredients that can be proven by science are used in the formulation of Circadia products. Michael Q. Pugliese, LE, grandson of Dr. Pugliese, is currently CEO of Circadia.

Key products and formulation

A popular Circadia product is the Micro-Exfoliating Honey Cleanser, which is formulated to gently cleanse and exfoliate while absorbing excess oil. This cleanser contains organic beeswax (cera alba). Beeswax is an excellent skin care ingredient because it creates a thin, protective layer over skin to help prevent loss of moisture. However, it seems as though this ingredient would be better suited in a moisturizer rather than a cleanser that is just going to be washed off of the face. A concerning ingredient found in this cleanser is cocamidopropyl betaine, a foaming agent derived from refined coconut oil. Even though coconut oil is well-known for being an excellent skin care ingredient, the chemical cocamidopropyl betaine is not. Many people have allergic reactions to this ingredient and it is known to cause burning and skin irritation, according to an article published in the journal Dermatitis.

Another key product is the Circadia Vitamin C Reversal Serum, which is said to increase the firm look of skin and neutralize free radicals. The form of vitamin C found in this serum is magnesium ascorbyl phosphate (MAP). Compared to L-ascorbic acid (the biologically active form of vitamin C), MAP is more stable and can also penetrate the skin better. This form of vitamin C is also known to have a hydrating effect on the skin and decreases transepidermal water loss. According to the Indian Dermatology Online Journal, magnesium ascorbyl phosphate is also a free radical scavenger that is photoprotective and increases collagen production under laboratory test conditions. This serum also contains hyaluronic acid and Vitamin B5. Overall, the ingredients in the Circadia Vitamin C Reversal Serum work to brighten and firm your complexion.

The final key product from the Circadia line is the AquaPorin Hydrating Cream. Aquaporins are integral membrane proteins that serve as channels in the transfer of water, and in some cases, small solutes across the cell membrane. Circadia suggests that by stimulating certain aquaporins, skin health can be improved. For example, the ingredient Diffuporine (acetyl hexapeptide-37) is said to boost aquaporin-3, which promotes inner hydration mechanisms and water movement from the basal layer of epidermis and to the stratum corneum, rejuvenating the skin by improving barrier function, collagen I synthesis and cellular proliferation. Similarly, Aquasense (Piptadenia colubrina extract) increases Aquaporins-3, 9, and 10 to hydrate skin, increases fibronectin, and envelope proteins to improve corneocyte cohesion. In addition to these ingredients that stimulate aquaporins, this cream also contains natural oils for their emollient, regenerative and soothing properties.

Compliment your regimen with a serum. Serum contains higher concentration of actives and penetrate deeper. We recommend  Carrot & Stick The Repair Serum. It contains 7 plant-based peptides to help promote smoother looking skin.


Since Circadia treatments and retail products are sold exclusively through estheticians and physicians, the company does not feature reviews on their website. These products are sold on Amazon and have received an overall positive response from consumers. All three of the key Circadia products mentioned above have received ratings of 4 or more stars.

The Circadia Micro-Exfoliating Honey Cleanser reviews state that this product helps to control breakouts and promotes softer skin. Fortunately, none of the reviews for this cleanser mention any irritation or allergic reactions from the ingredient cocamidopropyl betaine.

Reviews for the Circadia Vitamin C Reversal Serum are also very positive, with users saying they notice results such as brighter and more firm skin. None of the reviews mention any burning or skin irritation, which is a possible side effect from other vitamin C products.

The Circadia AquaPorin Hydrating Cream reviews state that this product is an excellent moisturizer, especially for those with dry skin. It will help to keep the skin hydrated for many hours while giving the skin a youthful, dewy glow. One review mentioned that this cream helped to improve rosacea symptoms.

In sum, the Circadia line of skin care products by Dr. Pugliese contain unique and effective ingredients that have been clinically proven to address a variety of skin concerns caused by disrupted circadian rhythms.

What Are Alternatives to Circadia Skin Care

If you’re looking for skincare products to address the signs of aging, we recommend Carrot & Stick. Carrot & Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin.



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