CeraVe Skin Renewing Night Cream - The Dermatology Review

CeraVe Skin Renewing Night Cream



CeraVe is a brand of dermatologist-developed skin care products that can alleviate a range of common skin concerns by starting at the source of the problem: the skin’s natural barrier. A strong, intact barrier is important to keep moisture in and keep things like allergens, bacteria, and irritants out. When the barrier is weakened, these intruders can pass through the top layer of skin, causing damage that ultimately leads to common skin conditions such as acne, rashes, sensitive skin, and even signs of aging.

Based on this concept, the dermatologists that developed the line of CeraVe products incorporated specific ingredients that would help to repair and strengthen the skin’s natural barrier. In this review on the CeraVe Skin Renewing Night Cream, we’ll discuss how this product can replenish your skin’s natural barrier overnight, allowing you to wake up with a healthy, radiant glow.

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What is it?

CeraVe Skin Renewing Night Cream is designed to deliver essential ceramides and other beneficial ingredients to your skin in a time-controlled manner throughout the night in order to replenish the skin’s natural barrier function.

Who is it for?

Cerave Skin Renewing Night Cream is suitable for all skin types, from oily to dry to combination skin. This product is said to address the following areas of concern:

  • Acne prone skin: By improving the skin’s barrier function, the Cerave Skin Renewing Night Cream helps to keep bacteria, dirt, and other impurities that are responsible for causing acne out of the skin.
  • Dry skin: The delivery of essential ceramides to the skin helps to rebuild the skin barrier, which increases the retention of moisture; exactly what dry skin needs!
  • Aging skin (fine lines and wrinkles): The Cerave Skin Renewing Night Cream contains biomimetic peptides that work to stimulate collagen production in order to reduce the appearance of fines lines and wrinkles.

Formulation insight

All CeraVe products, including the CeraVe Skin Renewing Night Cream, contain essential ceramides that your skin needs to help restore and maintain its natural protective barrier. Ceramides are lipids (oils) that are naturally produced by the skin and are vital in supporting the stratum corneum. The stratum corneum is the outer layer of skin, which can be thought of as a “brick and mortar” system. The bricks are the corneocytes (dead skin cells) and the intercellular lipids (ceramides) represent the mortar. Without ceramides, the skin barrier is weakened, just like without mortar a brick wall would be weak and unstable. The result is skin that can easily become dry, itchy, or irritated. Thus, a properly functioning stratum corneum is essential for healthy skin as it maintains epidermal hydration and serves as a barrier that responds to environmental stressors, infections, irritants, and allergens.

Topical application of ceramides on the skin can help to replenish ceramide levels, thus restoring the skin’s natural barrier. In order to facilitate the delivery of these essential ceramides to your skin, Cerave has developed something called MVE Delivery Technology. MVE stands for multivesicular emulsion and it represents a way of delivering ceramides to the skin in a time-release manner for a continuous rather than burst effect. In order to accomplish this, the MVE Delivery Technology contains layers of oil-in-water emulsions. A 2016 article published in The Journal of Clinical and Aesthetic Dermatology compares this technology to “nesting dolls” as one vesicle is contained within another inside the MVE. After applying CeraVe Skin Renewing Night Cream to the skin, there is a sequential opening of each vesicle, with a gradual release of the ceramides and other ingredient contents, rather than the burst of immediate release with some other products. What this means is that the CeraVe Skin Renewing Night Cream works throughout the night as your sleep to restore your skin’s natural barrier.

Another key factor in the formulation of CeraVe Skin Renewing Night Cream is biomimetic peptides. Peptides are short chains of two or more amino acids that have various roles throughout the human body. One function of peptides is cell-signaling, which is the communication between cells in order to coordinate certain actions. For example, according to research from the National Institutes of Health (NIH), when collagen is degraded it produces peptides that signal skin cells to generate more collagen. Since collagen degradation is a key factor in the appearance of aging skin, scientists have created biomimetic peptides which can mimic the effects of these naturally-occurring peptides. Therefore, by incorporating biomimetic peptides in the CeraVe Skin Renewing Night Cream, this product can improve the firmness and elasticity of skin by increasing collagen production.

How to use

After nighttime cleansing, apply the CeraVe Skin Renewing Night Cream right before going to bed. Use gentle, circular motions to massage this cream into the skin in order to make sure it is fully absorbed.


On the CeraVe website, the overall rating for the CeraVe Skin Renewing Night Cream is a 4.6 out of 5 stars. Multiple reviews say that this product outperforms other night creams on the market, even the more expensive brands, and that it is a very rich, thich moisturizer. Despite this rich texture, many reviewers point out that it does not leave their skin feeling greasy or oily. Furthermore, there are many comments that this product will help you achieve glowing, dewy skin by morning.

In sum, the CeraVe Skin Renewing Night Cream contains an innovative delivery technology to provide your skin with essential ceramides exactly when they’re needed in order to replenish the skin’s natural barrier function.




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