Olay Regenerist Serum - The Dermatology Review

Olay Regenerist Serum



What is the Olay Regenerist Serum?

Olay Regenerist Serum is a silky, ultra-lightweight gel serum that is said to regenerate surface cells while restoring skin’s elasticity. The serum penetrates the skin quickly and is designed to deliver moisturizing ingredients 10 layers deep into the skin surface. According to the brand, Olay Regenerist Serum will improve skin’s firmness after just 4 weeks while also reducing the appearance of fine lines and wrinkles. In this review, we’ll discuss the key ingredients in this serum, how to use it, Olay Regenerist Serum reviews from real customers, and more.

What are the Best Skin Care Products of 2021?

What Are The Key Olay Regenerist Serum Ingredients?

In order to determine if the Olay Regenerist Serum can provide all of the benefits we mentioned above, we must evaluate the key ingredients in the formula. The key ingredients in the Olay Regenerist formula include niacinamide, panthenol, tocopheryl acetate, and palmitoyl pentapeptide-4.

If you’ve read any of our Olay reviews, you know that Olay loves to use niacinamide in nearly all of their skin care products. Not surprisingly, niacinamide is a key ingredient found in Olay Regenerist Serum. Niacinamide is the amide form of vitamin B3 (niacin) and is a precursor to the coenzymes NADH and NADPH. These coenzymes play an important role in cellular metabolism, which means they provide skin cells with the energy needed to function properly. A publication in the Journal of Clinical and Aesthetic Dermatology, states that niacinamide can repair the skin barrier and improve skin moisture, as well as reduce inflammation, blotchiness, hyperpigmentation, acne, and wrinkling.

Another B vitamin in the Olay Regenerist Serum is panthenol (provitamin B5). Panthenol is a highly effective humectant, which means it has a molecular structure with several hydrophilic (water loving) groups. This structure allows humectants to attract and retain the moisture in the air nearby via absorption, drawing the water vapor into or beneath the surface of the skin. In addition to improving skin hydration, humectants like panthenol can help give the skin a more plump appearance.

Tocopheryl acetate is a form of vitamin E used in the Olay Regenerist Serum formula that provides powerful antioxidant properties and natural skin-conditioning effects. Vitamin E is the major lipid soluble antioxidant in skin. As an antioxidant, vitamin E has the ability to stop harmful free radicals right in their tracks, which is important because free radicals contribute to signs of aging, damaged cells, and mutated DNA. According to a 2016 publication in Dermatology News by Dr. Leslie Baumann, MD, vitamin E can protect the skin from both acute UV-induced damage as well as responses to chronic UVA and UVB exposure, including skin wrinkling and skin cancer. In addition to functioning as an antioxidant, tocopheryl acetate can help the skin retain moisture by strengthening the skin’s barrier function.

The final key ingredient in Olay Regenerist Serum is palmitoyl pentapeptide-4, a type of matrikine. Matrikines are messenger peptides that regulate cell activities through cell signaling. For example, when the collagen protein is degraded, matrikines send signals to fibroblasts to produce new collagen. Since matrikines have the ability to increase the production of collagen, elastin, and other macromolecules in the ECM, synthetic peptides like palmitoyl pentapeptide-4 have been created to mimic these effects. Thus, the inclusion of palmitoyl pentapeptide-4 in the Olay Regenerist Serum means you may notice an improvement in skin firmness.

Lastly, we’d like to point out that the Olay Regenerist Serum contains a high concentration of several different types of silicones, such as dimethicone, dimethicone crosspolymer, and polymethylsilsesquioxane. Silicones improve the spreadability of a product and impart a silky, smooth skin feel. In addition, silicones function as film-forming agents by forming an invisible film on the surface of the skin that helps the skin to retain moisture.

How to use Olay Regenerist Serum

After cleansing, apply Olay Regenerist Serum to your entire face and neck, morning and night.

Where is Olay Regenerist Serum sold?

Olay Regenerist Serum and other Olay skin care products are sold on the brand’s website, as well as third party ecommerce websites such as Amazon, eBay, Ulta, and more. You can also purchase Olay skin care products from drug stores like Walgreens, CVS, Walmart, Target, and more.

What is the Olay return policy?

The Olay return policy states, “You will be responsible for the shipping charges to return the item(s). To obtain your refund, the item must be returned to us, unopened and in its original packaging, with all accessories, within 30 days of the date upon which we provided the item to the carrier for shipment to you.”

Is Olay cruelty free?

Olay is not cruelty free. Olay is owned by Procter & Gamble, a company that tests on animals.

Olay Regenerist Serum reviews

Olay Regenerist Serum reviews on the brand’s website are a mix of positive and negative, with the product receiving an average rating of 4.2 out of 5 stars. There are many positive reviews for this serum that report it has a very nice silky texture that absorbs into the skin quickly. There are also quite a few Olay Regenerist Serum reviews that confirm this serum does provide noticeable results.

One very positive Olay Regenerist Serum review says, “I started using this product when it first went on the shelf and I am in my fifties and I can easily pass for my early thirties.

I know good genes help but from the time I started using it and the total effects daily moisturizer all those tiny wrinkles disappeared and even better the deep lines they haven’t appeared. I don’t have droopy skin in the neck and my skin remains smooth and supple.”

There are some negative Olay Regenerist Serum reviews from customers who were upset that Olay made changes to this formula. For example, one review from a long-time customer says, “My mom and I have used and recommend this product for over 8 years. This new formula is not working for me at all. Now I have no clue what product line to use, because I will not be purchasing this new formula. Wish I could insert a picture of my skin… I’ve always received compliments over the year and swore by this product as well as the daily facial cloth. I am disappointed, why change something if it’s not broken.”

What are some alternatives to Olay Regenerist Serum?

Overall, we think the Olay Regenerist Serum formula is good, but it’s very similar to many other Olay skin care products. The key ingredients in the serum (niacinamide, panthenol, vitamin E, palmitoyl pentapeptide-4) are beneficial, but they really aren’t unique. If you’ve tried products from the Olay Regenerist line without any results, you may want to consider an alternative to the Olay Regenerist Serum, such as Formulyst.

One Formulyst product we recommend is the Anti-Aging Concentrate, a highly concentrated formula that conditions your complexion and helps reduce the appearance of age spots, wrinkles, and fine lines. This serum contains natural ingredients like squalane, green tea, vitamin C, and vitamin E. All of these ingredients provide powerful antioxidant activity, protecting the skin against environmental free radicals that are known to degrade collagen. In addition, this serum contains Matrixyl 3000, a peptide complex that works to restore and maintain the skin’s youthful appearance by signaling to cells to produce more collagen. Overall, Formulyst Anti-Aging Concentrate is a multi-tasking serum that is formulated to help promote the five signs of youth – radiance, elasticity, firmness, skin tone and smoothness.

There’s no need to compromise when it comes to finding skincare that is effective and safe. Carrot & Stick takes a tough love approach to skincare, perfectly balancing the power of plants with cutting edge science. Not only is Carrot & Stick good for your skin, it is also good for the environment as the formulas skip harmful chemicals commonly found in skin care products.

1. J Clin Aesthet Dermatol. 2010 Feb; 3(2): 22–41
2. Dermatology News “Updated on Vitamin E” August 2016 Leslie S. Baumann, MD



Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds.Read More


The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants.Read More

Advanced Dermatology

The Advanced Dermatology skin care regimen addresses the most pressing aging concerns.Read More

No comments yet

Your Review

Recommended Articles

The Best Skincare Products of 2021

Uncategorized read more

Best Skin Care Routine

Uncategorized read more