ISDIN Skin Care Review



When you think of Spain, you might think of bullfighting or their beautiful beaches or even Pablo Picasso. But I bet you wouldn’t think of Spain as being home to one of the world’s top skin care brands, right? Named Spain’s number one dermatological company in 2015, ISDIN is a pharmaceutical skin care company that sells everything from top of the line anti-aging serums to their popular skin drops. If you want to learn more about how ISDIN has rose to be one of the top players in the skin care industry, keep reading below.

Brand background

Born 40 years ago in Barcelona from the alliance between a leading cosmetic company and a benchmark pharmaceutical company, ISDIN has a mission to create a worldwide reference in skin health, treatment, and beauty. The company works closely with doctors and pharmacists in order to create products that treat and correct a variety of skin concerns. Currently, ISDIN has products that either prevent or treat the signs of skin aging as well as several hair care products. They also aim to improve compliance by formulating products with unprecedented textures that will make product use easy and pleasurable. Today, ISDIN is a market leader in the dermo-cosmetics segment in Spain and a reference in Europe, America and Asia.

Key products

ISDIN has four different collections of products: Isdinceutics, Eryfotona Actinica, Lambdapil, and Uradin.

Isdinceutics is the brand’s anti-aging collection, which features eight unique products. One product from this line that is raved about is their Isdinceutics K-OX Eyes, a complete eye contour solution with three ingredients that reduce the appearance of puffiness and dark circles resulting in a fresh look. These three key ingredients include Vitamin K Oxide, Haloxyl and Eyeliss. Their theory is that since topical vitamin K has been known to speed the healing of bruises, using vitamin K oxide underneath the eyes will decrease the appearance of dark circles.

Another key product from the Isdinceutics line is the Melaclear Serum, a corrective serum boosted with vitamin C and phytic acid that is recommended to help even and fade out spots related to hyperpigmentation. Melaclear contains 8% L-ascorbic acid, the most active form of vitamin C. This ingredient works by slowing the production of melanin, the pigment in your skin that gives you a tan or creates age spots. Phytic acid also works to inhibit melanin production by blocking the entrance of iron and copper in the formation of melanin. One study reports that these two ingredients work synergistically to block melanin formation. By decreasing melanin production, Melaclear can prevent and fade dark spots, leaving your skin smooth and glowing.

One of the most popular ISDIN products, especially in the beauty industry, is their Isdinceutics Skin Drops. These ultra-light foundation drops conceal skin imperfections, such as vitiligo, discoloration, varicose veins, bruising, scars, burns and even tattoos. Isdinceutics Skin Drops come in three shades, Sand, Bronze and Caramel.

The Eryfotona Actinica brand contains just one product, which is their SPF 50+ mineral sunscreen. Dermatologists love this product because it contains DNA repair enzymes that have been shown to reduce the appearance of precancer more than just sunscreen alone. It is a zinc oxide-based formula, which means that this product acts as a physical sunscreen. Physical sunscreens protect your skin by using physical UV filters to block or deflect UV light. Common physical sunscreen ingredients include zinc oxide and titanium dioxide. Physical sunscreens tend to be better tolerated by most skin types because they are not absorbed into the skin. Thus, they are especially useful for those with heat sensitive skin (i.e. rosacea patients) as well as those with acne-prone skin as they are typically less pore-clogging.

ISDIN’s Lambdapil collection contains three hair care products that are designed to give you stronger, healthier hair after just three months of use. In addition to a revitalizing shampoo and lotion, Lambdapil also features an oral capsule that corrects thinning hair internally. The key ingredients in this capsule are B vitamins and L-cystine.

Lastly, Uradin is the brand’s line of products for the body, including a moisturizing body lotion and a hydrating gel oil for the feet. The Uradin 10 Lotion is specifically formulated for skin that is irritated, taut, or itchy. With key ingredients like urea and dexpanthenol, this lotion restores your skin’s natural smoothness and hydration. The Uradin Podos Hydrating Gel Oil contains skin-loving ingredients like glycerin, urea, and lactic acid in order to eliminate hard skin, roughness, and thickened skin on the heel and sole of the foot.


Interestingly, ISDIN reviews are mixed on The Derm Review. One review stated:  “The ceramic tip on the K-Ox eyes tube is soothing and cooling to touch. It sold me on the product. Nothing gets absorbed on the fingertips and right amount of pressure is exerted during application. A fabulous product with essential ingredients makes this a top of the line eye cream. The tube is small but it lasts a long time due to the application process.”




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  • Anne gault Original review: Feb 01, 2024. Reply

    I am wanting to purchase Isdin retinal intense 50, unfortunately I can’t find a stockist in Uk, I’ve always purchased this in Spain but Ive run out of my last bottle, is it possible to purchase on line, kind regards Anne Gault

  • Nancy Original review: Feb 21, 2021. Reply

    Flavo-C Ultraglican rates as close to a perfect product as one can get with one exception: the vial. I pour it into a sample size vial with a dropper. I use 6 drops in the palm of my hand and combine it with equal drops of Obagi 20% Vit C to get an extra Vit C boost. ISDIN truly needs to re-engineer the application process for the consumer. Genetics plays an important role in how the skin eve lives over time along with care and exposure. However, at 72 I can truthfully say I have no wrinkles except for a few around my mouth due to a hereditary factor. No laugh lines and I laugh all the time. No forehead crunch. I have the blessing of beautiful radiant skin. ISDIN is a contributor.

  • Nancy Original review: Feb 21, 2021. Reply

    The ceramic tip on the K-Ox eyes tube is soothing and cooling to touch. It sold me on the product. Nothing gets absorbed on the fingertips and right amount of pressure is exerted during application. A fabulous product with essential ingredients makes this a top of the line eye cream. The tube is small but it lasts a long time due to the application process.

  • Monique Original review: May 08, 2020. Reply

    I have been using Isdin SI-Nails for the past few months and I can’t see any improvement on my nails. I have kepted them clean and free of polish to favour Isdin Nail put on several times daily. No, not for me.

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    ISDIN Eryfotona Actinica Review

    Finding the right sunscreen can sometimes feel like finding a needle in a haystack. With so many formulas and so many different UV filters, it can be hard to figure out what works best with your skin. Some chemical filters make for an excellent skin-feel, but can spell trouble for those with sensitive or reactive skin. Some physical filters offer great protection for those with fragile skin, but can leave behind a noticeable white cast. Because sunscreen can be such a challenge, Isdin created the Isdin Eryfotona Actinica Broad Spectrum SPF 50+. This sunscreen is 100% mineral based, meaning that it only uses physical filters to protect the skin from UV damage. But while this product is mineral based, it also has a lightweight consistency, allowing it to blend into the skin seamlessly, giving you the best of both worlds. The brand also says that this product leaves behind no greasy residue or sticky feeling, allowing for easy makeup application over top. In order to get the best results from this type of product, and prevent premature aging and sun damage, we recommend applying this product once in the morning and then consistently throughout the day in order to maintain optimal protection.


    Isdin Melatonik Review

    Isdin Melatonik is a 3-in-1 night serum that is said to stimulate your skin’s natural antioxidant defenses, repair environmental stress and damages from the previous day, and support healthy, younger-looking skin. One of the key ingredients in this serum is melatonin. Melatonin is a hormone produced by the pineal gland in the brain that helps to regulate the circadian rhythm (sleep/wake cycle). In addition, melatonin receptors are expressed in many types of skin cells. Melatonin has strong antioxidant activity and works by neutralizing mainly hydroxyl radicals, the most damaging of all free radicals. Regarding UV-induced free radical damage, melatonin has the ability to counteract generation of reactive oxygen species, as well as protect against mitochondrial and DNA damage.

    Isdin Melatonik also contains bakuchiol, an east asian plant seed extract that provides many of the same benefits as retinol, including the ability to diminish the appearance of wrinkles and reduce the effects of sun damage (including uneven skin tone). One of the main benefits of bakuchiol is that it provides retinol-like effects without irritation. Isdin Melatonik contains vitamin C, a potent antioxidant that helps protect against oxidative damage. Vitamin C also serves as a cofactor for two enzymes involved in the synthesis of collagen, the protein that helps keep skin strong and firm. Lastly, vitamin C decreases melanin formation by inhibiting tyrosinase, an enzyme that is required for melanin synthesis. The result is skin that appears brighter with less dark spots and a more even skin tone.


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