Dr. Sister Skincare Reviews: A Review of The 5 Best Dr. Sister Skincare Products



After 43 years as a preeminent expert in the field of anti-aging skincare, Dr. Daniel Sister has created a line of products that are meant to help you feel youthful and confident at any age, with a natural look that lasts morning through night. 

In a world where skincare brands often make bold claims, it’s essential to delve deeper and examine the ingredients to determine the true effectiveness of their products. And that’s exactly what we’re going to do in this review. 

Below we’ll cover the formulation details, including the key ingredients in Dr. Sister Skincare Products and the research that supports (or doesn’t support) their use in skincare. 

We’ll also share some Dr. Sister Skincare reviews so that you can get an idea of what customers really think of these products.

What Are The Top 5 Best Dr. Sister Skincare Products?

The Dr. Sister Skincare line currently consists of five products to treat various skin concerns, from dark spots to wrinkles to crepey skin and more. Here’s a breakdown of each Dr. Sister Skincare product: 

Dr. Sister Skincare Dark Spot Vanish

Dr. Sister Skincare Dark Spot Vanish is formulated to deeply penetrate to address the root causes of dark spots with key ingredients like Bicowhite Complex and niacinamide. 

Bicowhite Complex has targeted delivery of 5 different whitening ingredients to specific skin layers where each ingredient is most effective. The 5 whitening ingredients each play a different role in de-pigmentation processes and preventing the formation of dark spots.

Niacinamide is another ingredient in Dr. Sister Skincare Dark Spot Vanish that helps to reduce hyperpigmentation and brighten the complexion. In a study published in the British Journal of Dermatology, niacinamide was found to significantly decrease hyperpigmentation and increase skin lightness compared with vehicle alone after 4 weeks of use.

Dr. Sister Skincare Younger You Skin Cream

Younger You Skin Cream is rich in chronobiological cell energizers and collagen-enhancing ingredients, aimed at reversing the signs of skin aging.

Chronodyn energizes skin cells, reducing wrinkles and promoting a firmer appearance. Matrigenics 14 G enhances skin’s lifting and firming effects by reactivating collagen, elastic fibers, and hyaluronic acid genes. Revivyl supports a healthy skin microbiome, activating skin stem cells and natural cell turnover for a healthier complexion. 

Pentavitin provides deep, long-lasting hydration and helps smooth wrinkles. CITYSTEM acts as a protective “Skin Shield” against pollution and blue light, preventing premature aging.

Dr. Sister Skincare Inner Beauty

If the thought of taking a daily supplement to improve the look of your skin sounds like something you’d be interested in, then Dr. Sister Inner Beauty could be a good option for you. It’s a dietary supplement that’s said to help you achieve more youthful skin thanks to a combination of vitamins, minerals, and skin-supporting ingredients like hyaluronic acid. 

The formula also includes SOD B Dimpless, a potent molecule designed to combat cellulite effectively. Plus, the inclusion of ingredients like Mesoporosil and Biotin helps to promote healthier hair and nails, too. 

Dr. Sister Skincare Crepe Rewind

Dr. Sister Skincare Crepe Rewind is an advanced firming complex specifically designed to address the look of thin, wrinkled, and “crepey” skin across the entire body. This skin-smoothing cream combines deep hydration, collagen-boosting elements, and firming agents, delivering both immediate and sustained results.

For instance, Hydranov, a red algae complex, increases skin hydration significantly, resulting in smoother and plumper skin for up to 72 hours. Dermosculpt acts as a “collagen builder,” rejuvenating skin texture and firmness in a matter of weeks. 

Inst’tight C reduces the appearance of wrinkles, sagging, and crepey lines in just 3 minutes, offering an almost instant “skin perfecting” effect. Reforcyl supports the skin barrier, locking in vital moisture while safeguarding against age-accelerating factors like pollution and UV light. VITASMOOTHY, derived from butterfly lavender, effectively regenerates skin’s water reserves by 69% and repairs even the driest areas, providing luxurious hydration.

What Are The Key Ingredients in Dr. Sister Skincare Products?

There’s not just one key ingredient that’s used in Dr. Sister skincare products, but rather a combination of tried-and-true ingredients, such as niacinamide and hyaluronic acid, with innovative ingredients, such as Bicowhite Complex, Pentavitin, and Revivyl, just to name a few. 


One concern we have with Dr. Sister Skincare products is the use of fragrance, which can be a problem due to the potential to cause contact allergies, skin irritation, and even skin damage. 

For example, Dr. Sister Dark Spot Vanish contains fragrance ingredients like limonene, coumarin, alpha-isomethyl ionone, and citronellol. All fragrance ingredients (whether natural or synthetic) impart scent through a volatile reaction, and this natural reaction almost always causes a sensitizing reaction on skin.

Even if you don’t have a full blown reaction to the ingredient, the damage may still be occurring every day. Ultimately, this can cause mild problems for your skin in the short term and worse problems in the long term.

How Much Do Dr. Sister Skincare Products Cost?

Dr. Sister Skincare products are mid-range in terms of cost; they aren’t cheap but they are ridiculously expensive. For example, the Dr. Sister Dark Spot Vanish costs £89.00 for 50 mL (1.75 fl oz). 

Where to Buy Dr. Sister Skincare Products?

Dr. Sister Skincare Products are sold exclusively on the brand’s website. Is Dr. Sister Skincare Cruelty Free?

Yes, Dr. Sister Skincare is cruelty free. 

Dr. Sister Skincare Reviews

Dr. Sister Skincare reviews on the brand’s website are overall very positive, however, there aren’t very many customer reviews. Reviews for the Dark Spot Vanish are all four- or five-star ratings. 

Our Verdict

Overall, we like that Dr. Sister Skincare products are formulated with a combination of tried-and-true ingredients and innovative ingredients. However, we’re concerned that the products contain fragrance. 


  • Formulas contain beneficial key ingredients
  • Cruelty free
  • Many positive Dr. Sister Skincare reviews


  • Formulas contain fragrance
  • Mid-range cost


Br J Dermatol 2002 Jul;147(1):20-31.



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