CLEARSTEM Skincare Reviews: A Review of The 5 Best CLEARSTEM Skincare Products



CLEARSTEM Skincare, established in 2017 by Danielle Gronich and Kayleigh Christina, emerged from Danielle’s extensive experience as a Licensed Clinical Esthetician and the founder of the San Diego Acne Clinic. 

With a 98% success rate in clearing patients’ skin, Danielle, also known as The Acne Guru™, collaborated with Kayleigh Christina, a Certified Holistic Nutritionist, who successfully addressed her own cystic acne through Danielle’s holistic approach. 

Bonding over their shared commitment to holistic health, they delved into clinical research, unveiling the harsh reality of conventional skincare — most acne products contain harmful ingredients, and those targeting aging are laden with pore-clogging fillers. 

Driven to provide a safer alternative, Kayleigh and Danielle united to create CLEARSTEM, the first toxin-free brand addressing both acne and aging simultaneously.

Below we’ll discuss the best-selling CLEARSTEM Skincare products, including the key ingredients and CLEARSTEM reviews so that you know what to expect before trying these products. 

What Are The Top 5 Best CLEARSTEM Skincare Products?

CLEARSTEM Skincare offers everything that you would need to create a complete skincare routine, including cleansers, moisturizers, serums, sunscreens, and more. Here’s a breakdown of the top 5 best CLEARSTEM Skincare Products. 

CLEARSTEM MIND BODY SKIN Hormonal Acne Supplement

If the thought of taking a daily supplement to reduce acne breakouts and improve the look of your skin sounds like something you’d be interested in, then you’ll want to consider this CLEARSTEM supplement. 

This best-selling oral supplement is formulated for both men and women who struggle with adult hormonal acne. It addresses breakouts in several ways, targeting multiple root causes simultaneously.

By combining DIM, vitamin B5, bioavailable vitamin A, glutathione, turmeric, milk thistle, and digestive enzymes, the formula helps your body to optimize digestion and detoxification while regulating the hormones that lead to acne.

According to the brand, you can expect to see clearer skin in 7 to 10 days with continued results that progress over time.


HYDRAGLOW is a stem cell moisturizer with key ingredients bakuchiol (a plant-based retinol alternative), plant stem cells, and squalane. Together, these ingredients should help to reduce the appearance of lines and wrinkles while promoting soft, moisturized skin. Despite its rich texture, this facial moisturizer is acne-safe! 


The name of this serum implies that you can use it as an alternative to Botox, which is a pretty bold claim. So what ingredients in this serum will help to smooth away lines and wrinkles?

Looking at the ingredient list, we noticed there’s a blend of growth factors, peptides, and collagen-derived stem cells. While these ingredients should help to promote skin repair, it’s unlikely that you’ll notice similar results as Botox. 

CLEARSTEM CELLRENEW Collagen Stem Cell Serum

This CLEARSTEM serum contains extracts from saw palmetto, green tea, and reishi mushroom to regulate oil production, while turmeric and B5 reduce inflammation, allowing skin to re-balance and heal. There’s also a blend of collagen stem cells and hyaluronic acid, making this serum a great choice for those who want to combat signs of aging and acne. 

CLEARSTEM CLEARITY “The Blackhead Dissolver”

This CLEARSTEM serum dissolves blackheads thanks to mandelic acid, a type of alpha hydroxy acid (AHA). 

As an AHA, mandelic acid has the ability to exfoliate the skin, stimulate the skin’s natural regeneration process, and help the skin to retain moisture. It exfoliates the skin by targeting corneocytes (dead skin cells) in a process called corneocyte desquamation. 

By enhancing their breakdown and increasing the separation of skin cells, the rate of cell turnover is increased, leading to smoother, more radiant skin — and fewer blackheads!

The formula also contains vitamin C and turmeric, which are known to help brighten the complexion and even out skin tone. 

How Much Do CLEARSTEM Skincare Products Cost?

CLEARSTEM Skincare products are mid-range in terms of cost; they aren’t cheap but they are ridiculously expensive. 

For example, the HYDRAGLOW™ Stem Cell Moisturizer costs $56 USD for 2 fl oz (60 mL), while the BOUNCEBACK™ “No Botox Serum” costs $98 USD for 1 fl oz (30 mL). 

Where to Buy CLEARSTEM Skincare Products?

CLEARSTEM Skincare Products are sold on the brand’s website, as well as on 

Is CLEARSTEM Skincare Cruelty Free?

Yes, CLEARSTEM Skincare is cruelty free. 

Our Verdict

Overall, we think that CLEARSTEM Skincare products are formulated well with evidence-based key ingredients, and we appreciate the brand’s holistic approach to skincare. 


  • Products are formulated with evidence-based key ingredients
  • CLEARSTEM is cruelty free
  • Many positive CLEARSTEM Skincare reviews


  • Some products contain fragrant essential oils



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