CLEARSTEM Skincare Reviews: A Review of The 5 Best CLEARSTEM Skincare Products



CLEARSTEM Skincare, established in 2017 by Danielle Gronich and Kayleigh Christina, emerged from Danielle’s extensive experience as a Licensed Clinical Esthetician and the founder of the San Diego Acne Clinic. 


1Carrot & Stick Review

With a 98% success rate in clearing patients’ skin, Danielle, also known as The Acne Guru™, collaborated with Kayleigh Christina, a Certified Holistic Nutritionist, who successfully addressed her own cystic acne through Danielle’s holistic approach. 

Bonding over their shared commitment to holistic health, they delved into clinical research, unveiling the harsh reality of conventional skincare — most acne products contain harmful ingredients, and those targeting aging are laden with pore-clogging fillers. 

Driven to provide a safer alternative, Kayleigh and Danielle united to create CLEARSTEM, the first toxin-free brand addressing both acne and aging simultaneously.

Below we’ll discuss the best-selling CLEARSTEM Skincare products, including the key ingredients and CLEARSTEM reviews so that you know what to expect before trying these products. 

What Are The Top 5 Best CLEARSTEM Skincare Products?

CLEARSTEM Skincare offers everything that you would need to create a complete skincare routine, including cleansers, moisturizers, serums, sunscreens, and more. Here’s a breakdown of the top 5 best CLEARSTEM Skincare Products. 

CLEARSTEM MIND BODY SKIN Hormonal Acne Supplement

If the thought of taking a daily supplement to reduce acne breakouts and improve the look of your skin sounds like something you’d be interested in, then you’ll want to consider this CLEARSTEM supplement. 

This best-selling oral supplement is formulated for both men and women who struggle with adult hormonal acne. It addresses breakouts in several ways, targeting multiple root causes simultaneously.

By combining DIM, vitamin B5, bioavailable vitamin A, glutathione, turmeric, milk thistle, and digestive enzymes, the formula helps your body to optimize digestion and detoxification while regulating the hormones that lead to acne.

According to the brand, you can expect to see clearer skin in 7 to 10 days with continued results that progress over time.


HYDRAGLOW is a stem cell moisturizer with key ingredients bakuchiol (a plant-based retinol alternative), plant stem cells, and squalane. Together, these ingredients should help to reduce the appearance of lines and wrinkles while promoting soft, moisturized skin. Despite its rich texture, this facial moisturizer is acne-safe! 


The name of this serum implies that you can use it as an alternative to Botox, which is a pretty bold claim. So what ingredients in this serum will help to smooth away lines and wrinkles?

Looking at the ingredient list, we noticed there’s a blend of growth factors, peptides, and collagen-derived stem cells. While these ingredients should help to promote skin repair, it’s unlikely that you’ll notice similar results as Botox. 

CLEARSTEM CELLRENEW Collagen Stem Cell Serum

This CLEARSTEM serum contains extracts from saw palmetto, green tea, and reishi mushroom to regulate oil production, while turmeric and B5 reduce inflammation, allowing skin to re-balance and heal. There’s also a blend of collagen stem cells and hyaluronic acid, making this serum a great choice for those who want to combat signs of aging and acne. 

CLEARSTEM CLEARITY “The Blackhead Dissolver”

This CLEARSTEM serum dissolves blackheads thanks to mandelic acid, a type of alpha hydroxy acid (AHA). 

As an AHA, mandelic acid has the ability to exfoliate the skin, stimulate the skin’s natural regeneration process, and help the skin to retain moisture. It exfoliates the skin by targeting corneocytes (dead skin cells) in a process called corneocyte desquamation. 

By enhancing their breakdown and increasing the separation of skin cells, the rate of cell turnover is increased, leading to smoother, more radiant skin — and fewer blackheads!

The formula also contains vitamin C and turmeric, which are known to help brighten the complexion and even out skin tone. 

What Are The Key Ingredients in CLEARSTEM Skincare Products?

The CLEARSTEM Skincare products contain a variety of evidence-based key ingredients, such as vitamin C, peptides, and bakuchiol, just to name a few. Let’s take a closer look at the benefits that these ingredients offer.

Vitamin C

We’ve been hearing for years that Vitamin C is the best anti-aging ingredient. It’s a potent antioxidant that protects the skin from free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin.

Vitamin C also helps fade dark spots, evens out skin tone, and increases radiance. As if that wasn’t enough, research suggests that when vitamin C is applied to the skin, it significantly reverses aging-related structural changes by influencing collagen and elastin synthesis. 

It’s in CLEARSTEM CLEARITY “The Blackhead Dissolver”. 

But our favorite Vitamin C serum is Carrot & Stick The Defence Serum. It contains 3 distinct types of Vitamin C that work together to help fight free radical damage. We recommend using it every morning.


As you age, your body’s production of collagen and elastin slows down. These two proteins are responsible for your skin’s structural support. As a result, the skin loses its natural plumpness and smoothness. 

While collagen is necessary for maintaining youthful-looking skin, the collagen protein is too large to absorb into the skin topically. That’s why applying skin care products that contain collagen won’t provide the anti-aging benefits you’re looking for.

This is where peptides come into action. Peptides are the building blocks of protein, and they are easily absorbed into the deeper layers of skin due to their smaller size. 

CLEARSTEM BOUNCEBACK “No Botox Serum” contains three different peptides that offer anti-aging benefits. 

If you’re looking for a potent peptide serum, we recommend Carrot & Stick The Repair Serum. It contains 7 plant-based peptides to promote plumper and smoother-looking skin. It also has skin-loving ingredients like hyaluronic acid and niacinamide.

Bakuchiol (Retinol Alternative)

If you’re trying to prevent or reduce signs of skin aging, then you’ve probably heard that it’s a good idea to add a retinol serum into your nightly routine. Maybe you’ve tried a retinol product, but you’ve experienced the common (yet annoying) side effects of retinol, like skin dryness and peeling. 

If so, the CLEARSTEM HYDRAGLOW Stem Cell Moisturizer could be a good option due to the key ingredient bakuchiol, a plant-based retinol alternative. 

Bakuchiol has been shown to produce many of the same effects of using retinol, including the ability to diminish the appearance of wrinkles and reduce the effects of sun damage (including uneven skin tone). One of the main benefits of bakuchiol is that it provides retinol-like effects without irritation.

Another retinol alternative is Hydroxypinacolone Retinoate (HPR), which you’ll find in this retinoid oil serum. We recommend this serum because HPR provides similar benefits as retinol with less irritation.

How Much Do CLEARSTEM Skincare Products Cost?

CLEARSTEM Skincare products are mid-range in terms of cost; they aren’t cheap but they are ridiculously expensive. 

For example, the HYDRAGLOW™ Stem Cell Moisturizer costs $56 USD for 2 fl oz (60 mL), while the BOUNCEBACK™ “No Botox Serum” costs $98 USD for 1 fl oz (30 mL). 

Where to Buy CLEARSTEM Skincare Products?

CLEARSTEM Skincare Products are sold on the brand’s website, as well as on 

What is The CLEARSTEM Skincare Return Policy?

The CLEARSTEM Skincare return policy states, “We accept returns from within 30 days of delivery. If you have purchased a product from one of our authorized retail partners, please follow that retailer’s return policy.”

Is CLEARSTEM Skincare Cruelty Free?

Yes, CLEARSTEM Skincare is cruelty free. 

CLEARSTEM Skincare Reviews

CLEARSTEM Skincare reviews on the brand’s website are overall very positive. One of the products with the most reviews is the CLEARSTEM acne supplement, which has earned an average rating of 4.7 out of 5 stars after more than 600 customer reviews. 

There are many raving 5-star reviews for the CLEARSTEM acne supplement from customers who experienced reduced acne breakouts and clearer skin very quickly after starting this supplement. 

For example, one review says, “This supplement started working for me almost immediately. I had a small breakout around a week in but cleared up after and have stayed clear. I’ve been on accutane 3 TIMES and have tried everything and my acne has always came back. This pill along with using the rest of the clearstem line and cutting out gluten has actually changed my life!!

However, there are a handful of negative reviews for the CLEARSTEM acne supplement, which are primarily from customers who didn’t see the results they were hoping for with this product. 

For example, one review says, “Have been using it for a month with no results. Will try another month and hope for the best, but morale is low considering you’re supposed to see results in 2-3 weeks.”

Our Verdict

Overall, we think that CLEARSTEM Skincare products are formulated well with evidence-based key ingredients, and we appreciate the brand’s holistic approach to skincare. 


  • Products are formulated with evidence-based key ingredients
  • CLEARSTEM is cruelty free
  • Many positive CLEARSTEM Skincare reviews


  • Some products contain fragrant essential oils

What Are Some Alternatives to CLEARSTEM Skincare Products?

If you’re looking for skincare products to address the signs of aging, we recommend Carrot & Stick. Carrot & Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin. We recommend the Day & Night Routine. This 24-hour skincare routine will defend against and help repair visible signs of aging by addressing fine lines and wrinkles. 



Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds. Read More


The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Read More

No comments yet

Your Review

Recommended Articles