Atopalm MLE Cream Review



Atopalm is a Korean beauty brand that formulates products for sensitive skin, including the very popular Atopalm MLE Cream. 

Created with Atopalm’s patented MLE technology, Atopalm MLE Cream is formulated to mimic the structure of the natural skin lipids, thereby aiding their replenishment in the stratum corneum.

In addition, this cream helps prevent the evaporation of the skins’ moisture and protects the entire face from environmental stresses, leading to softer skin.

What are the Best Skin Care Products of 2023?

However, after evaluating the Atopalm MLE Cream formula, we actually would not recommend this product for sensitive skin. Why? Keep reading to learn the pros and cons of Atopalm MLE Cream.

We’ll also share some Atopalm MLE Cream reviews so that you can get an idea of what customers really think of this product

Is Atopalm MLE Cream Right For You?

Before we get into the details, here’s the TL;DR if you just want to know whether or not  Atopalm MLE Cream is right for you.

  • Key ingredients? Glycerin, Emollients, Myristoyl/palmitoyl oxostearamide/arachamide mea, Vitamin E, Purslane
  • Skin type? Can be used by all skin types, ideal for dry skin
  • Texture? Rich cream
  • Fragrance? Yes
  • Cruelty free? Yes
  • Cost? $25.20 USD for 3.4 oz

What Are The Key Ingredients in Atopalm MLE Cream?

In order to determine how well Atopalm MLE Cream performs, we’ll have to evaluate the key ingredients in this formula. Let’s get started.

Myristoyl/palmitoyl oxostearamide/arachamide mea
When the brand refers to the ‘MLE Technology’ in Atopalm MLE Cream, they are referring to the ingredient called “Myristoyl/palmitoyl oxostearamide/arachamide mea”.

This name is very long and hard to pronounce, but it’s actually an excellent skin care ingredient. 

According to dermatologist Dr. Leslie Baumann, Myristoyl/palmitoyl oxostearamide/arachamide mea —  also referred to as multi-lamellar emulsion (MLE) technology — is a lab-created ingredient known to mimic the natural lamellar structure of your skin’s lipids that comprise the skin barrier. 

The skin barrier can be thought of as a “brick and mortar” system. The bricks are the corneocytes (dead skin cells) and the intercellular lipids (ceramides, fatty acids, and cholesterol) represent the mortar. 

Without these lipids, the skin barrier is weakened, just like without mortar a brick wall would be weak and unstable. The result is skin that can easily become dry, itchy, or irritated. 

Therefore, Using a moisturizer with MLE technology is great for those with very dry skin, including chronic conditions like eczema, because the skin barrier is weakened in these conditions. 

In fact, studies have shown that applying MLE formulations directly to the skin can improve skin barrier function by imitating the structure of its natural lipids.

There’s a high concentration of glycerin, a type of humectant, in Atopalm MLE Cream. 

A humectant is a hygroscopic substance that has a molecular structure with several hydrophilic (water loving) groups. These groups hydrogen bond with water, essentially “grabbing” it and holding it on the skin.

Humectants pull water from the dermis to the epidermis and stratum corneum. In addition, humectants can draw water vapor from the air to help moisturize the skin if the humidity is over 50 percent.

Atopalm MLE Cream also contains many different emollients, including caprylic/capric triglyceride, cetearyl alcohol, glyceryl stearate, grape seed oil, hydrogenated vegetable oil, olive oil, and jojoba oil. 

An emollient is an oily substance that fills in the spaces between dead skin cells, thus creating a smooth skin surface. Basically, an emollient is a film forming substance that makes the skin feel and look smooth. While an emollient will provide some occlusive effects, the primary function is to help soften the skin

Vitamin E
Atopalm MLE Cream also features vitamin E as a key ingredient. Vitamin E is a “chain-breaking” antioxidant because it can hinder the chain reaction induced by free radicals, according to a publication by Dermatology News. This is important because free radicals contribute to signs of aging, such as fine lines, wrinkles, sagging skin, and age spots. 

Another function of vitamin E is to help the skin retain moisture by strengthening the skin’s barrier function. When vitamin E is delivered to your skin through the sebaceous (oil) glands, it improves water-binding capacity and hydrates the stratum corneum (the uppermost layer of skin). 

Synthetic Fragrance
So far, the Atopalm MLE Cream formula sounds pretty good, right? It is, but unfortunately there’s a big problem with this formula: it contains a synthetic fragrance blend. 

The use of synthetic fragrance ingredients can be a problem because the brand can use a proprietary blend of chemicals to create the fragrance. On average, this consists of 30 to 50 chemicals (but it can have as much as 200 components). 

Want to know the worst part? The brand does not have to disclose which chemicals they use on the label. They are allowed to list this blend as “Fragrance (Parfum)” on the ingredient list.

2018 study by Women’s Voices for the Earth discovered that in over 3,000 chemicals reportedly used for fragrances, 1,242 were chemicals of concern – and that included at least 7 possible carcinogenic (cancer-causing) agents. 

Furthermore, fragrance ingredients have the potential to cause skin irritation and sensitivity reactions. This is a major problem because Atopalm MLE Cream is marketed for those with sensitive skin!

Due to the inclusion of fragrance in this formula, we cannot recommend Atopalm MLE Cream.

How to Use Atopalm MLE Cream?

After cleansing, apply all over dry areas. Use as often as necessary, paying special attention to those stubborn, troublesome dry spots on elbows, knees and heels.

Where to Buy Atopalm MLE Cream?

Atopalm MLE Cream and other Atopalm skin care products are sold on the brand’s website (, as well as on several third party websites such as Amazon, iHerb, CostCo, PeachandLily, and more. 

How Much is Atopalm MLE Cream?

Atopalm MLE Cream costs $25.20 USD for 3.4 oz on the brand’s website. 

What is The  Atopalm Return Policy?

The Atopalm return policy states, “Are you unhappy with your order? If so, you may return your item(s) for an exchange or refund within 14 days of the shipping date.”

Is Atopalm Cruelty Free?

Yes, Atopalm is cruelty free. 

Atopalm MLE Cream Reviews

Atopalm MLE Cream reviews on the brand’s website are mostly very positive, but there aren’t that many reviews at this time, so we went over to to get a better idea of what customers think of this product. 

On Amazon, Atopalm MLE Cream has received an average rating of 4.5 out of 5 stars after more than 500 customer reviews. 

There are many 5-star reviews for Atopalm MLE Cream from customers who love that it hydrates and softens skin without feeling greasy or heavy. 

For example, one review says, “I have used all kinds of moisturizer from Olay to La Mer, and SK-II. This is by far the best product I have used any time and any season and will continue to purchase them again and again!!!”

And another 5-star review says, “At 62 years of age my skin was starting to get very dry, therefore I cannot believe how smooth and soft my skin feels after using this cream and what’s more you need so little. The size of a pea and your face is completely covered, so although expensive it will last for months. Other ladies have actually commented on my complexion, so I would definitely recommend this wonderful cream.”

However, there are a handful of negative reviews for the Atopalm MLE Cream, which are mostly from customers who had allergic reactions to the fragrance in this product. 

For example, one review says, “This is the worst cream I’ve EVER used; not only does it smell of chemicals, but my skin also broke out horribly–something it never does. I’ve used a lot of moisturizing creams, but I am sending this one back–it’s THAT BAD!

A similar 1-star review says, “I was recommended this product to help with my severe eczema, so I assumed that it would be unscented, but it has a strong floral scent, and “fragrance” listed in the ingredients. I tried it twice but on my sensitive dry face, it turned it red and burned. Sadly a waste of money. Please don’t buy it for eczema or sensitive skin.”

Our Verdict

Overall, we don’t recommend Atopalm MLE Cream due to the inclusion of fragrance in this product, which is one of the worst things for those with dry, sensitive skin!


  • Formula contains beneficial key ingredients
  • Many positive Atopalm MLE Cream reviews
  • Atopalm is cruelty free


  • Product contains a synthetic fragrance blend, which can cause skin sensitivity reactions

What Are Some Alternatives to Atopalm MLE Cream?

If you’re looking for skin care products to address the signs of aging, one brand we recommend is Formulyst. Formulyst maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in clinically advanced skin care solutions that help promote healthy, more youthful-looking skin.

For example, Formulyst’s Anti-Aging Concentrate can help to address multiple signs of aging at once. This serum contains natural ingredients like squalane, green tea, vitamin C, and vitamin E, which provide powerful antioxidant activity to protect the skin against environmental free radicals that are known to degrade collagen. In addition, this serum contains Matrixyl 3000, a peptide complex that works to restore and maintain the skin’s youthful appearance by signaling to cells to produce more collagen.

Another brand that balances the power of plants with cutting edge science is Carrot & Stick. Not only is Carrot & Stick good for your skin, it is also good for the environment as the formulas skip harmful chemicals commonly found in skincare products.

J Invest Dermatol. 2003 Oct; 121(4): 794-801
Dermatology News “Update on Vitamin E” Aug 2016
Women’s Voices for the Earth “Unpacking The Fragrance Industry” 2018



Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds. Read More


The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Read More

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