Saccharide isomerate is carbohydrate complex formed from a mixture of plant-derived saccharides (sugars). Specifically, saccharide isomerate is obtained from the D-glucose of wheat. It is designed to mimic a carbohydrate complex that is found in the Natural Moisturizing Factor (NMF) of the stratum corneum. After being absorbed through the skin, saccharide isomerate binds to an amino group of lysine in the keratin of corneocytes (dead skin cells). Due to this unique binding mechanism, saccharide isomerate cannot be washed off easily. Ultimately, this enables it to provide the skin with hydration until it is removed during the skin’s natural exfoliation process. The manufacturer reports that saccharide isomerate can generate a moisture reservoir that lasts for 72 hours. Saccharide isomerate is primarily used in creams, lotions, and other types of moisturizers, especially those for dry, flaky skin.