Mesoestetic Dosmelan 2 Review - The Dermatology Review

Mesoestetic Dosmelan 2 Review



Cosmelan 2 is the second part of the Cosmelan Depigmentation System by Mesoestetic. The first part of the system is a chemical peel that must be applied by a physician. Cosmelan 2 is the topical anti-spot cream for home use after the peel, or it may be used alone. It is a lightweight cream that is intended to treat discoloration, brown spots, and dark patches. The key ingredients in Cosmelan 2 include kojic acid and phytic acid. Kojic acid is a very potent tyrosinase inhibitor. Tyrosinase is a key enzyme involved in the synthesis of melanin, the pigment that gives skin color. Therefore, by inhibiting tyrosinase, kojic acid is able to reduce abnormal pigmentation associated with aging and exposure to UV light. Phytic acid also works to inhibit melanin production by blocking the entrance of iron and copper in the formation of melanin.

In addition to these two skin lightening agents, Cosmelan 2 contains the antioxidants vitamin C (ascorbic acid) and vitamin A (retinyl palmitate). Both of these antioxidants offer protection against environmental free radicals. Vitamin C is also known to brighten the complexion and fade dark spots. Retinyl palmitate has the ability to minimize the appearance of fine lines and wrinkles, improve uneven skin tone, restore skin firmness, and shrink the appearance of enlarged pores. Overall, Cosmelan 2 provides you with an at-home solution for treating hyperpigmentation and maintaining results gained from the Cosmelan peel.


When you see “water\aqua\eau” on a product’s ingredient label, it simply means water. Manufacturers of cosmetics and personal care products are required by law to list all of the ingredients...

Titanium Dioxide

Titanium dioxide is the naturally occurring oxide of the element titanium. In cosmetics and personal care products, titanium dioxide functions as a sunscreen active ingredient, pigment, and thickener. Titanium dioxide

Octyl Methoxycinnamate

Cetearyl Alcohol

Cetearyl alcohol is a fatty alcohol used as an emollient, emulsion stabilizer, surfactant, opacifying agent, and a viscosity-increasing agent in cosmetics and personal care products....

Sodium Lauryl Sulfate

Sodium Cetearyl Sulfate

Paraffinum Liquidum

Paraffinum liquidum, also referred to as liquid paraffin, is the latin name for mineral oil. It is acceptable to use the term “paraffinum liquidum” on a product’s ingredient list, however,

Kojic Acid

The name kojic acid derives from “Koji”, the Japanese common name for a species of fungi known as Aspergillus oryzae. During the fermentation of malting rice, for use in the...

Butyl Methoxydibenzoylmethane

One of the more effective ways to take care of your skin is to protect it from the sun with sunscreens containing ingredients like avobenzone, which absorb UV radiation. While...

Phytic Acid

Phytic acid is the phosphate ester of inositol, a carbocyclic sugar. Phytic acid naturally occurs in seeds, grains, legumes, nuts, and some vegetables. It is sometimes classified as an alpha...

Ascorbic Acid

Ascorbic acid is another name for vitamin C, an antioxidant that is popular in skin care products due to its ability to brighten skin, reduce the appearance of fine lines...

Retinyl Palmitate

Retinyl palmitate is a type of retinoid that is used in skin care products due to its ability to improve signs of aging, hyperpigmentation, and acne....





Methylchloroisothiazolinone, also referred to as MCI, is a preservative with antibacterial and antifungal activity. It is effective against gram-positive and gram-negative bacteria, yeast, and fungi. Methylchloroisothiazolinone has been used in


Methylisothiazolinone is a powerful synthetic biocide and preservative within a group known as  isothiazolinones. In cosmetics and personal care products, it is used for controlling microbial growth in water-containing solutions.

No comments yet

Your Review

Recommended Articles