LeanBiome Review: Do Probiotics Help With Weight Loss?



LeanBiome is a probiotic supplement specifically formulated to help you lose weight by reversing the bacterial imbalance in your gut microbiome. 

The brand explains that recent research suggests that gut dysbiosis (an overgrowth of “bad” bacteria in the gut) is the newly-discovered root cause of belly fat and unexplained weight gain.

Further reading: Best supplements 2024.

So does LeanBiome work? To answer that question, we’ll thoroughly review the product formulation based on what the current medical research has found about the benefits of these ingredients. 

We’ll also share some LeanBiome reviews from real customers so that you can get their take on the results of this supplement. 

What Are The LeanBiome Ingredients?

LeanBiome contains nine clinically-researched ‘lean bacteria’ species. Below we’ll focus on the species that have the most research to support their benefits, and we’ll touch on a few of the other key ingredients in this formula. 

Lactobacillus Gasseri

In a 12-week clinical trial featured in the British Journal of Nutrition, 210 overweight volunteers were split into two groups: one consuming milk with L. Gasseri while the other drank plain milk as a placebo. 

The L. Gasseri group experienced an average reduction of 8.5% in belly fat, along with significant decreases in overall body weight, BMI, waist size, and visceral fat. 

In the control group, none of these parameters significantly decreased from baseline.  

Additionally, discontinuation of L. Gasseri intake resulted in halted fat loss and a reversal of improvements, highlighting the species’ effectiveness in appetite control, metabolic enhancement, and fat reduction. 

Lactobacillus Rhamnosus 

Another “lean” bacteria species in the LeanBiome formula is Lactobacillus Rhamnosus, which also has a study published in the British Journal of Nutrition

In this study, the subjects were split into two groups — one taking L. Rhamnosus formulation and the other taking placebo — for a 24 week period. 

Each group was submitted to moderate calorie restriction for the first 12 weeks, followed by 12 weeks of weight maintenance.

The mean weight loss in women in the L. Rhamnosus group was significantly higher than that in women in the placebo group after the first 12 weeks. 

Women in the L. Rhamnosus group continued to lose body weight and fat mass during the weight-maintenance period, whereas opposite changes were observed in the placebo group

Lactobacillus Fermentum

The final ‘lean’ bacteria species that you’ll find in the LeanBiome formula is called Lactobacillus Fermentum. 

A clinical trial published in the Journal of Functional Foods found that L. Fermentum produced a 3% drop in body fat in just 43 days, compared to just 1% for the placebo group.

Put simply, within just six weeks, this particular species tripled the rate of fat loss, even though both groups adhered to identical diets. 


The prebiotic in this formula is called inulin, a type of fiber derived from chicory root. Prebiotics are non-digestible fibers that serve as “food” for the beneficial bacteria in the gut. 

A 2020 study examined the impact of inulin on gut microbial composition through a review of human studies. In these studies, participants consumed 2g to 20g of inulin daily, and results revealed a substantial positive effect on the human gut microbiome.

Unfortunately, the amount of inulin in LeanBiome (only 200 mg) is substantially less than the amount used in studies!

Greenselect Phytosome

Greenselect Phytosome is a proprietary lecithin formulation of a caffeine-free green tea catechin extract. 

In a clinical trial published in the journal Evidence-Based Complementary and Alternative Medicine, 50 overweight men and women were given 300mg per day of Greenselect Phytosome and put on a calorie-controlled diet. The other 50 trial participants were put only on the diet.

After 90 days, the average weight loss in the Greenselect Phytosome group was 30 lbs, compared to just 11 lbs for the diet-only group.

What Are The Benefits of LeanBiome?

After reviewing the various ingredients and probiotics used in LeanBiome, we’ve summarized the benefits you may notice with this product:

May Help With Weight Loss

The combination of the three ‘lean’ probiotic species with Greenselect Phytosome may help to promote weight loss, as evidenced by the clinical trials we cited above. However, it’s important to note that these studies typically incorporated low-calorie diets and exercise regimens alongside the supplement, emphasizing the necessity of a comprehensive approach to achieve optimal results.

May Promote Better Digestion

Another purpose of the probiotics in LeanBiome is to help maintain the balance of the gut microbiome by preventing the overgrowth of “bad” bacteria. A balanced gut microbiome is crucial for supporting digestion and overall health. 

What Are The LeanBiome Side Effects?

Like any dietary supplement, there is a possibility of experiencing side effects. 

The side effects that are typically associated with pre- and probiotic supplements include stomach upset, gas, diarrhea, or bloating.

Always consult with your healthcare provider before incorporating any supplements into your routine to ensure they align with your individual health needs and medical conditions.

Where to Buy LeanBiome?

LeanBiome is sold on the brand’s website (, as well as on Amazon.

How Much is LeanBiome?

On the brand’s website, one bottle of LeanBiome (one month supply) costs $59 USD plus $9.95 shipping. 

On Amazon, one bottle of LeanBiome (one month supply) costs $58 USD. 

What is The LeanBiome Return Policy?

LeanBiome offers a 180-day money back guarantee that states, “I’m so confident you’ll be head-over-heels thrilled with the results you get that I’m giving you a full six months to try LeanBiome for yourself, completely risk-free, regardless of the package you choose. If you change your mind for any reason at all, simply contact my friendly customer support team, and they’ll refund 100% of the purchase price, no questions asked.”

LeanBiome Reviews

In our opinion, Amazon provides a more reliable source for genuine customer reviews compared to a brand’s official website.

On, LeanBiome has earned an average rating of only 3.7 out of 5 stars after more than 200 customer reviews. 

There are many 5-star reviews for LeanBiome from customers who love that it helps to reduce cravings and really works to promote weight loss. 

For example, one review says, “This product worked great for me! I’ve already lost 5 pounds after using it for a month as stated in the description. I also had little to no cravings whilst on the pills, and I didn’t have to alter anything in my routine to get these results.”

And another 5-star review says, “I like this product very much. It has been helping me to shed some of my stubborn belly fat. With the help of some dieting and light exercise LeanBiome is a great helper in getting my body healthier!”

However, there are a handful of negative LeanBiome reviews, which are mostly from customers who were disappointed that they didn’t see the results they were hoping for with this product. 

For example, one review says, “Followed the instructions and saw no change in weight at all. I included working out and eating healthy.”

Another 1-star review says, “I have been taking it for a month and I have not seen any weight loss results I have actually gained 4 lbs since being on it!”

Our Verdict

While there is research to support the benefits of the probiotics in LeanBiome, based on the LeanBiome reviews it’s clear that this supplement doesn’t work for everyone. 


  • Research supports the weight loss effects of the probiotics in this formula
  • May help to improve digestion 
  • 180-day money back guarantee


  • Inadequate amount of inulin in the formula
  • Low overall customer rating (3.7 out of 5 stars on Amazon)

What Are Some Alternatives to LeanBiome?

If you’re looking for an alternative to LeanBiome, below we’ll link to other probiotic supplements that are formulated specifically for weight loss:

  • ProbioSlim Review: ProbioSlim is a dietary supplement sold by the brand Force Factor that promises benefits such as healthy digestion, gut health, more energy, and weight loss. 
  • Provitalize Review: Provitalize is a probiotic supplement that’s claimed to naturally manage abdominal fat during menopause, as well as improve digestion, ease hot flashes, support joint health, increase energy, and more. 

Br J Nutr. 2013 Nov 14;110(9):1696-703.
Br J Nutr. 2014 Apr 28;111(8):1507-19.
J. Funct. Foods 2013 Jan;5(1):116-123.
Evid Based Complement Alternat Med. 2013; 2013: 869061.



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