Gundry MD Total Restore Review



Total Restore is a digestive supplement sold by Gundry MD, the brand of health and wellness products by cardiologist Dr. Steven Gundry. 

Formulated with 20 pro-digestive ingredients, Total Restore is claimed to be “scientifically shown to support a strong, healthy gut lining” and, therefore, provide benefits such as promoting smooth digestion, comfortable bowel movements, curbing unhealthy cravings for junk food, increased energy, and more. 

Further reading: Best supplements 2024.

So does Gundry MD Total Restore live up to these claims? To answer that question, we’ll thoroughly review the product formulation based on what the current medical research has found about the benefits of these ingredients. 

We’ll also share some Total Restore reviews from real customers so that you can get their take on the results of this supplement. 

What Are The Gundry MD Total Restore Ingredients?

The Total Restore formulation contains over 20 “gut-boosting” compounds, including both natural and synthetic ingredients. Below we’ll give you the details on the ingredients that have the most research to support their benefits. 


PepZinGI is a combination of Zinc and L-carnosine. This novel compound has been shown in studies to offer a variety of gut health benefits, including its anti-ulcer properties, maintaining the bacterial balance of the stomach and GI tract, preventing free radical damage to gastric cells, and more. 

For example, in a randomized, placebo-controlled, double blind study, 299 patients suffering with symptoms of gastric discomfort were randomly allocated to receive either a PepzinGI or a placebo, or a control drug or its placebo for 8 weeks. 

Out of the 258 trial completers, 136 belonged to the PepzinGI group, where 92% of participants exhibited a rating of “moderately improved” or higher on an improvement scale for symptoms like heartburn, tenderness, epigastric pain, diarrhea, and constipation after 8 weeks.


L-glutamine is a naturally-occuring amino acid that has many important functions in the body, such as removing excess ammonia (waste product in the body), as well as supporting immune system function, brain function, and digestion. 

Supplementing with L-Glutamine offers several benefits. In regards to gut health, L-glutamine has been shown to reduce intestinal inflammation and also help people recover from food sensitivities. 

For instance, a study in the journal Clinical Immunology revealed that L-glutamine helps regulate the TH2 immune response, which triggers inflammatory cytokines, thereby restoring immune balance. 

In simpler terms, the findings from this study indicate that having the right amount of glutamine in the body might affect how the body reacts to various germs and foreign substances.

L-glutamine also contributes to maintaining a balanced gut microbiome by inhibiting the overgrowth of bacterial pathogens.

L-glutamine supplements are typically dosed between two to five grams (G). Unfortunately, there’s only 213 milligrams (mg) used in the Gundry MD Total Restore supplement!

Licorice Root Extract

Licorice root extract is rich in numerous beneficial compounds, one being glycyrrhizin. Glycyrrhizin has antioxidant, antimicrobial, and anti-inflammatory properties, which may help to reduce inflammation and soothe GI discomfort. 

Licorice root may also help to maintain a balanced gut microbiome. For example, a 2016 study found that licorice root helped eliminate a bad gut bacteria called H. pylori, which can cause peptic ulcers.

N-Acetyl D-Glucosamine (NAG)

N-Acetyl D-Glucosamine (NAG) is a form of glucosamine, which is a precursor to glycosaminoglycans (GAGs) found in the gut lining.

NAG is believed to support gut health by promoting the repair and maintenance of the intestinal mucosal lining while also reducing intestinal inflammation and permeability (also referred to as leaky gut).

Additionally, NAG may contribute to the growth of beneficial gut bacteria and help reduce the adherence of harmful pathogens to the gut lining, thereby supporting a healthy, balanced gut microbiome.


Berberine is a naturally occurring compound found in goldenseal, Oregon grape, turmeric, and other plants. It has antimicrobial and anti-inflammatory properties, which may help support the gut microbiome of people with bacterial overgrowth due to irritable bowel syndrome, ulcerative colitis, and other inflammatory bowel diseases.

For example, a randomized, placebo-controlled trial featured in the journal Phytotherapy Research administered 400 mg of berberine daily for eight weeks to patients with diarrhea-predominant IBS. Results from this trial demonstrate that berberine reduced diarrhea frequency, urgency, and abdominal pain.

Unfortunately, the dose of berberine in Gundry MD Total Restore is only 3 mg! This is significantly lower than the 400 mg dosage used in the aforementioned study. 

What Are The Benefits of Gundry MD Total Restore?

After reviewing the various ingredients and probiotics used in Gundry MD Total Restore, we’ve summarized the benefits you may notice with this product:

Balanced Microbiome

There are many ingredients in Total Restore that help to maintain the balance of the gut microbiome by preventing the overgrowth of “bad” bacteria. A balanced gut microbiome is crucial for maintaining overall health, supporting digestion, immune function, and even mental well-being.

Reduce Intestinal Inflammation

Several of the ingredients used in Total Restore have anti-inflammatory properties, which means they should help to reduce intestinal inflammation. Reducing intestinal inflammation can alleviate discomfort, promote proper nutrient absorption, and support overall gut health.

Where to Buy Gundry MD Total Restore?

Gundry MD Total Restore is sold on the brand’s website (, as well as on 

How Much is Gundry MD Total Restore?

On the brand’s website, Total Restore costs $69.95 USD for a 30 day supply (the member price is $49.95). 

On, Total Restore costs $44.95 for the same amount.

What is The Gundry MD Return Policy?

The Gundry MD return policy states, “We offer a 90-Day Money Back guarantee on all Products purchased through our Website. Your guarantee comes into effect on the day your Product is shipped from our fulfillment center, and expires ninety (90) days after the shipped date.”

Gundry MD Total Restore Reviews

In our opinion, Amazon provides a more reliable source for genuine customer reviews compared to a brand’s official website.

On, Gundry MD Total Restore has earned an average rating of 3.9 out of 5 stars after more than 9,000 customer reviews. 

There are many 5-star reviews for Gundry MD Total Restore from customers who love that it helps reduce stomach pain, promotes more regular bowel movements, and improves energy levels. 

For example, one review says, “This definitely helped reduce my hard-to-define stomach discomfort after about a week of use. After the first month, I have no stomach discomfort at all. It is just gone. I have less gas/bloating, and it also helped well with regularity.” 

And another 5-star review says, “The first day I took this supplement, i didn’t feel the pain anymore but was a bit groggy. By day 3 I had great energy and felt pain free in my intestines.”

However, there are a handful of negative reviews for the Gundry MD Total Restore, which are mostly from customers who didn’t notice any benefits from this product.  

For example, one review says, “After a month of use, I have not lost a single pound, and there is zero change to my overall health.”

Another 1-star review says, “Does not work at all, I used one full bottle and do not feel any difference or any results, save your money as it is not worth it and is very expensive.”

Our Verdict

Overall, we think that there are beneficial ingredients in Gundry MD Total Restore, however, many of them are used in very low doses. 


  • Many of the ingredients have research to support their gut health benefits
  • Many positive Gundry MD Total Restore reviews
  • 90-Day Money Back guarantee


  • Most of the ingredients are used in very low doses
  • Some reviews mention that the product did not provide any benefits

What Are Some Alternatives to Total Restore?

If you’re looking for alternatives to Gundry MD Total Restore, check out our reviews for these gut supportive supplements:

  • Align Probiotics Review: Align is a brand that offers a variety of supplements to help support your gut health and daily wellness.
  • Activated You Morning Complete: Morning Complete is formulated with a custom-selected blend of nutrients designed to support regular digestive function, daily energy levels, and overall wellness. 

Miyoshi A, et al.: Jpn PharmTher 1992;20(1):199-223.
Clin Immunol. 1999 Dec;93(3):294-301.
Braz J Infect Dis. 2016 Nov-Dec;20(6):534-538.



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