Dr. Denese Reviews



Harvard and Cornell trained physician Adrienne Denese, M.D. Ph.D, has devoted her career to creating topical treatments for aging skin in her brand known as Dr. Denese SkinScience. Dr. Denese has been featured on PBS, QVC shows and infomercials, Cosmopolitan, Elle, and ABC. In this review, we’ll discuss a few of the brand’s best selling products, key ingredients, Dr. Denese reviews from real customers, an alternative for you to consider, and more. 


1Carrot & Stick Review
-Dr Denese


What’s Inside Dr. Denese Skin Care?

There really isn’t just one key ingredient that can be found in every single Dr. Denese Skin Care product. Rather, the brand uses a variety of beneficial ingredients, such as Vitamin C, peptides, and retinol. These ingredients should all be part of your skincare routine.

Vitamin C
We’ve been hearing for years that Vitamin C is the best anti-aging ingredient. It’s a potent antioxidant that protects the skin from free radicals, the unstable molecules that contribute to the formation of premature wrinkles and fine lines on the skin.

Vitamin C also helps fade dark spots, evens out skin tone, and increases radiance. As if that wasn’t enough, research suggests that when vitamin C is applied to the skin, it significantly reverses aging-related structural changes by influencing collagen and elastin synthesis.

It’s in Dr. Denese Pro C Clinical PM Brightening Serum. 

But our favorite Vitamin C serum is Carrot & Stick The Defence Serum. It contains 3 distinct types of Vitamin C that work together to help fight free radical damage. We recommend using it every morning.

As you age, your body’s production of collagen and elastin slows down. These two proteins are responsible for your skin’s structural support. As a result, the skin loses its natural plumpness and smoothness. 

While collagen is necessary for maintaining youthful-looking skin, the collagen protein is too large to absorb into the skin topically. That’s why applying skin care products that contain collagen won’t provide the anti-aging benefits you’re looking for.

This is where peptides come into action. Peptides are the building blocks of protein, and they are easily absorbed into the deeper layers of skin due to their smaller size. 

Dr. Denese Triple Strength Peptide Super Drops contains several peptides known to combat aging and help promote skin barrier function and repair. 

If you’re looking for a peptide serum, we recommend Carrot & Stick The Repair Serum. It contains 7 plant-based peptides to promote plumper and smoother-looking skin. It also has skin-loving ingredients like hyaluronic acid and niacinamide.

Retinol is the go-to anti-aging ingredient recommended by dermatologists and skin experts. It’s clinically proven to minimize the appearance of fine lines and wrinkles, improve uneven skin tone, restore skin firmness, and shrink the appearance of enlarged pores.

The only downside? Retinol can often lead to side effects like skin dryness, peeling, and irritation. 

It’s in Dr. Denese SkinScience HydroShield Ultra Moisturizing Face Serum, as well as in Dr. Denese Triple Strength Peptide Super Drops. 

Use retinoids at night. We recommend this retinoid oil serum.  It contains Hydroxypinacolone Retinoate, an ingredient that provides similar benefits with less irritation.

What are the best selling Dr. Denese Skin Care products?

Dr. Denese suggests following her Six Step Skin Care Program every night to successfully address the eight visual signs of aging skin. However, if you’re not ready to invest in six products from this brand, we recommend starting with one of these best selling Dr. Denese Skin Care products:

Dr. Denese HydroShield Ultra Moisturizing Face Serum
Dr. Denese HydroShield Ultra Moisturizing Face Serum is a hydrating serum that is said to lock in moisture to drastically reduce the look of dry lines and wrinkles and to plump the appearance of the skin. This Dr. Denese serum is meant for those with dry to normal skin types. If your skin is oily, you can still use this serum, but place it only around the eyes and neck and on dry patches–not on the oily T-zone.

Dr. Denese Hydrating Cleanser
Another best selling Dr. Denese Skin Care product is the Hydrating Cleanser. This cleanser can be used by all skin types and is said to hydrate and clean the skin while also delivering antioxidants, vitamins, and lipids to the skin at the same time. 

Dr. Denese Advanced Firming Facial Pads
Dr. Denese Advanced Firming Facial Pads are exfoliating facial pads that work by removing dead old skin cells and facilitating the rise of fresh young skin cells to the surface. The Dr. Denese firming facial pads are meant for anyone who is dealing with dull skin, uneven skin tone, enlarged pores, and fine lines and wrinkles. 

Where is Dr. Denese Skin Care sold?

Dr. Denese Skin Care is sold on the brand’s website, as well as QVC and Amazon. 

What is the Dr. Denese return policy?

The Dr. Denese return policy states that returns are accepted within 30 days of package arrival. However, the brand does not accept returns on products that have been heavily used, and original shipping and handling charges are non-refundable. 

Are Dr. Denese products cruelty free?

Dr. Denese products are cruelty free and the brand can be found in PETA’s Beauty without Bunnies Cruelty Free Database. The brand states, “We at SkinScience Labs, Inc. do not believe in animal testing. None of our vendors, suppliers or raw material producers perform any type of animal testing.”

Dr. Denese reviews

Dr. Denese reviews on the brand’s website are overall very positive, with most products receiving 4 and 5 star ratings. 

Several positive Dr. Denese reviews for the HydroShield Ultra Moisturizing Face Serum mention that it leaves the skin feeling clean, moisturized, and silky. However, there are several reviews for this product that mention it has an oily feel when applied. For example, one reviewer shares, “It seems to go on oily but soon it absorbs. I’m not really seeing much change in my face or wrinkles so I’d say the product is ok but overpriced.”

The Dr. Denese Hydrating Cleanser reviews mention that it is refreshing, gentle, and does not dry out the skin. There are also several reviews that say it removes makeup well. For example, “Love how this product removes all my make up including mascara and leaves my skin moisturized and not dry.” However, some customers find this cleanser to be too rich and others experienced breakouts after using it. 

Positive reviews for the Dr. Denese Firming Facial Pads mention that these pads really do help to minimize the look of pores and keep the skin very smooth. One long time customer says, “I have been using Dr. Denese’s Advanced Firming Facial Pads for many, many years and they have made my facial skin look fantastic. My pores are nonexistent now and my face looks and feels so firm and smooth.” There aren’t any negative reviews for this product at the moment. 

What are some alternatives to Dr. Denese Skin Care?

If you’re looking for skincare products to address the signs of aging, we recommend Carrot & Stick. Carrot & Stick maximizes the use of powerful ingredients and minimizes the use of superficial ones, resulting in advanced skincare solutions that help promote healthy, more youthful-looking skin. We recommend the Day & Night Routine.



Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds. Read More


The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Read More

Dr. Denese Med Md 33 Neck Cream Review

So many skincare lovers focus their skincare on the facial skin and forget to treat the neck as well. To help with this issue, brands like Dr. Denese have created entire ranges dedicated to address neck-related skin concerns. Unfortunately, products like the Dr. Denese Med MD 33 Neck Cream have been discontinued and are no longer available on the company’s website. With that said, you can still find this product through a few stockists including Amazon, QVC and Ebay. Additionally, Dr. Denese offers a full range of skincare products that focus on the neck area, that work similarly to the Med MD 33 Neck Cream. This includes products like the their Triple Strength Neck Wrinkle Smoother, and the Neck Saver Firming Pads. These products all feature key ingredients such as their unique triple strength peptide technology to plump and smooth the skin while boosting collagen production as well.


Dr. Denese Hydroshield Dream Cream Review

If you’re currently battling with extremely dry skin this season, you may want to try the Dr. Denese Hydroshield Dream Cream. This product has been designed to plump and hydrate the skin after only one use. This product features the brand’s unique Intelligent Hydration Technology, which is able to locate the dry patches on your skin and effectively treatment with the highly moisturizing and nourishing ingredients. In addition to finding the driest area on your skin, this product also helps to retain moisture. Transepidermal water loss is one of the most common reasons why your skin experiences extreme dryness and sensitivity. Improving your skin’s natural ability to retain moisture is critical to normalizing your skin and managing dryness long term.


Dr. Denese Essential Lipid Power Infusion Review

The Dr. Denese Essential Lipid Power Infusion is a balancing serum that aims to help boost and heal the skin using a number of powerful dry plant oils and beneficial antioxidants. This serum contains over 6 plant oils including macadamia nut oil, avocado oil, argan oil, olive oil, amaranth seed oil, and rosehip seed oil which help to soften and smooth the skin, as well as reveal a radiant glow. These oils are all incredibly rich, which make them ideal for those with extra dry or mature skin types that tolerate plant oils well. In addition to this plant oils, the formula behind the Essential Lipid Power Infusion also contains a variety of antioxidants to help fight against free radicals including chamomile extract and resveratrol. Together, these ingredients are rich in essential vitamins, minerals and nutrients that help to keep the skin healthy. That being said, this is an incredibly rich product and because of this, can be potentially pore clogging, so we recommend patch testing before incorporating it into your everyday skincare routine.


Dr. Denese Firming Facial Collagen Night Serum Review

The Dr. Denese Firming Facial Collagen Night Serum was designed to serve as a nighttime treatment to help boost firmness and suppleness while you sleep. This product uses a number of sophisticated technologies in order to deliver a potent dose of hydrating and age-defying ingredients. Starting off with hydration, this formula features three different weights of hyaluronic acid, which help to deliver vital hydration to different layers within the skin, results in thorough hydration and plumpness. Secondarily, this product also features their SoluXome technology. This unique delivery system helps to ensure that the skin is able to effectively use all of the beneficial ingredients that are contained within the formula. Some of these active ingredients include several fruit derived alpha hydroxy acids as well as soluble collagen to help with exfoliation and brightening. In clinical trials, the Facial Collagen Night Serum was able to significantly improve tightness, skin firmness and elasticity.


Dr. Denese Hydroshield Ultra Moisturizing Face Serum Review

Dr. Denese is known for their anti-aging moisturizing products, such as the Hydroshield Ultra Moisturizing Face Serum. This product was designed to intensely moisturize and hydrate the skin. As we age, dryness can become more and more apparent, and it can cause your wrinkles and fine lines to become more obvious. In order to prevent this, it’s important to use the right products that hydrate and plump the skin without being too rich. The Ultra Moisturizing Face Serum uses HydroShield Technology in order to do just that. This technology includes a blend of important ingredients including ceramides, soy, vitamin E, retinol, linoleic acids, EFA, and glycolipids which target many of the factors that contribute to dryness. Ceramides and soy help to reinforce the skin’s natural moisture barrier, while linoleic acids and vitamin E help to soften the give and deliver that radiant glow. Additionally, actives like retinol help to address the anti-aging concerns that often go hand and hand with increased dryness and dehydration.

  • Kay Original review: Aug 19, 2023. Reply

    The tinted sunscreen is such an amazing product!!! It makes me love sunscreen! So creamy and light, the tint blends perfectly with any skin type and gives you coverage too.
    It’s my new go to daily sunscreen when going out. I love this product!

  • Janice Original review: Sep 23, 2022. Reply

    Thank you for your honesty!
    Karen, truth is so important! Many
    People believe these claims because they want so desperately to look younger. I happen to be in my 70s and if you met me, you would think I
    Was much younger. Just keep your face out of the Sun and always wear sunblock!
    Make sure that your moisturizer and foundation have an SPF. Lots of luck!

  • karen bulmer Original review: Jan 25, 2019. Reply

    Do not buy this product until you read all the charges that you’re going to incur after you purchase it. it is very expensive and I saw no results that they claim.

  • Your Review
    User Rating: 0.0 (0 votes)

    Recommended Articles