plus-icon

Bioma Review: Does It Really Work?

SKIN CARE REVIEWS

02.07.24DISCLAIMER

Bioma, operating from Lithuania, is a probiotics company offering a supplement claim to foster gut health, reduce IBS symptoms and facilitate weight loss. Bioma is a Lithuanian company that manages some manufacturing of their product in the USA. The distribution is managed by Max Nutrition LLC in San Francisco, USA. 

Although specific details about the founders and researchers responsible for the formulation are undisclosed, Christine, Bioma’s Chief Dietitian, emphasizes that Bioma is crafted to be the ‘ultimate probiotic for sustained weight loss.’ 

Further reading: Best supplements 2024.

Does the research support these claims? Keep reading to learn more about the key ingredients inside Bioma, the potential benefits of this supplement, what side effects to look out for, and more. 

We’ll also share some customer reviews so you can get to know if the product is for you.

What Is Bioma? 

Bioma is a supplement claiming to offer benefits for gut health and weight loss. 

Like most probiotics on the market today, Bioma aims to support the gut microbiome. As you will have likely heard, the gut microbiome, often aptly named ‘the body’s second brain’ is a complex and intricate ecosystem of microorganisms that seem to have a significant influence on your overall health. 

The scientific literature continues to grow with studies that support the idea that the gut microbiome influences, digestion, mental health, and support your immune system. 

It is important to note at this point that while the literature is amassing, many studies on the benefits of specific strains are still in their infancy, having yet to progress to human trials. 

With that in mind, the Bioma formulation claims to specifically address or ‘start fixing’ issues such as constipation, diahorea, bloating, nausea and weight loss. 

The supplement incorporates key ingredients like xylooligosaccharide (XOS) a prebiotic, thermogenic probiotics, and tributyrin postbiotic to promote a balanced gut environment. 

Scientific studies are cited to validate the effectiveness of Bioma, emphasizing its unique combination of prebiotics, probiotics, and postbiotics as a comprehensive approach. However, when you dive a little deeper it becomes unclear as to whether the science actually backs this specific formulation. 

Bioma’s website emphasizes that individual experiences may vary, and users are advised to consult healthcare professionals before incorporating Bioma into their routine. 

Does Bioma Actually Personalise Thier Product To You? 

Part of Bioma’s selling point is that they give you information on your ‘gut type’ and provide you with personalised advice. 

The results of the ‘gut type’ quiz give you generalised, supportive advice that is designed to be incorporated into your daily routine, such as gentle movement. 

Despite Bioma having a personalized ‘gut typing’ quiz on their website which you need to fill out in order to purchase, there is no personalization in the product you receive. While the content highlights the supplement’s ingredients, mechanisms of action, and potential benefits, it does not indicate that Bioma tailors its product to specific user profiles. 

The absence of customization is underscored by the information that Bioma only produces a single product.

 It is recommended for individuals interested in understanding their digestive type to take the quiz on the Bioma website, but it’s important to note that consumers should be aware of the product’s general features and consult healthcare professionals for personalized advice and guidance.

What Are The Three Main Ingredients In Bioma?

Bioma’s formulation includes three main ingredient types: 

Xylooligosaccharide
Xylooligosaccharide (XOS) is a type of prebiotic. For those who may not be familiar with exactly what a prebiotic is, let us explain. 

A prebiotic is a non-digestible ingredient that supports the growth and activity of bacteria in the gut. Think of it as the bacteria’s food. XOS, specifically, is a complex carbohydrate composed of xylose sugar molecules. 

In a 2021 review article published in Frontiers in Nutrition Xylooligosaccharides, may have protective benefits to the body. 

It is often derived from plants such as corn, sugarcane, rice and wheat. 

Some studies support the use of XOS in probiotic formulations to support the growth of beneficial bacteria in the gut.

As a prebiotic, XOS serves as a source of nourishment for beneficial bacteria, helping them thrive and contribute to a balanced and harmonious gut environment. This, in turn, is believed to support various aspects of health, in particular healthy digestion and may help to improve nutritional absorption. 

As a side note, most formulations containing XOS are unlikely to contain as much of the ingredient as what has been tested in a research setting. This is in part the reason that a healthy balanced diet with other sources of insoluble fibre is important to gut health. 

Tributyrin 

Naurally found in butter, this ingredient, according to a PLOS One research article, support intestinal barrier repair’ 

Tributyrin is a chemical that acts as a precursor for butyric acid. Butyric acid is a short-chain fatty acid that is essential for many physiological activities, particularly those in the gastrointestinal tract. 

It has been reported that the roles of tributyrin in antibiotic-induced gut microbiota disorders are unclear. This shows that, while tributyrin may benefit certain aspects of gut health, its precise effect on microbiome disruptions caused by antibiotic use is not well understood.

Many of the studies that have been conducted on this ingredient have been mice studies which can be hard to extrapolate to benefits in humans. 

Proprietary Blend – Bifidobacterium lactis, Bifidobacterium longum, and Bifidobacterium breve

Bifidobacterium lactis, Bifidobacterium longum, and Bifidobacterium breve are commonly known and researched probiotic strains. They are recognized for their potential benefits in supporting gut health, digestion, and immune function. However, the specific strains and their concentrations in a probiotic supplement can vary between products. 

As Bioma uses a blend that is proprietary it is hard to know whether the concentrations would be considered beneficial. Their dietary information notes that it contains 9 billion Colony Forming Units or CFUs. 

CFU, or Colony Forming Units, is a standard unit of measurement used to quantify the viable microorganisms, such as bacteria or yeast, in a probiotic supplement. This measurement is crucial in assessing the potency and effectiveness of the probiotic product. 

Other Ingredients 

On Bioma’s dietary information includes four other ‘non-active ingredients’. They include microcrystalline cellulose, hypromellose, magnesium sterate and silicone dioxide. These ingredients are likely used to stabilise the formulation or are present in the capsule that contains the probiotic. 

What Do Probiotics Do? 

Probiotics are beneficial bacteria that can help support your health. Your gut has a large amount of naturally occurring bacteria that help with immune health, digestion, and some studies suggest, mental health. With our modern diets, medications and lifestyles it can be easy for the balance of bacteria to get out of whack, this is where probiotics may support your health.  

Here are the main benefits of probiotics:

  1. Gut health: This is the most general benefit. Probiotics help to maintain a balanced and healthy gut microbiome. They help balance the ‘good’ and ‘bad’ bacteria in the gut. 
  2. Digestive support: Research suggests that probiotics may help you to digest and absorb nutrients better, improving nutrition. 
  3. Immune support: Probiotics may work by interacting with our immune system, defending your body against harmful pathogens.
  4. Soothing irritation: A 2021 article in Frontiers in Immunology, discusses how certain strains of probiotics may have anti-inflammatory benefits to your gut. , 
  5. Mental health: This is an interesting one, you may think that probiotics wouldn’t affect your mental health. There is growing research that suggests that there is a strong link between the gut and the brain and that the balance and types of bacteria in the gut may have an effect on your mental wellbeing. 
  6. Post-antibiotic care: After you take a course of antibiotics, you may have been told by your health professional to try probiotics. This is because antibiotics, while treating your infection, may kill off some of the bacteria in the gut. This may result in an imbalance in types and numbers of bacteria usually present. 
  7. Gut-related symptoms: Probiotics may offer relief for those of us who have some trouble with their gut, such as those who experience Irritable Bowel Syndrome (IBS). However, it is important to note that much of the research suggests that there are specific strains that are more useful in these cases than others. 

It’s important for us to acknowledge that the efficacy of specific probiotics can vary significantly based on the strains used, dosage, and individual health conditions. 

Seeking advice from a healthcare professional can help determine the most appropriate support for you.

What Are The Benefits of Bioma?

Now that you know the general benefits that research suggests probiotics may have to your overall health we can run through Bioma’s claims. Bioma Probiotic’s websites boasts a range of potential benefits for your overall well-being, especially when it comes to your gut health and managing your weight.

  1. Gut health: Bioma claims to help with symptoms such a diahorea, contipsation, bloating and nausea.
  2. Weight loss: This is one of the biggest claims made by the brand. While there is some evidence to suggest that some probiotics can support in weight loss, the research is limited and does not necessarily include the strains present in the Bioma Probiotic. 
  3. Broad overall health benefits: The Bioma website discusses potential benefits to the hair, skin, muscle and heart health. Be mindful that this is an extrapolation of information relating to all probiotics, often at much higher doses and does not account for Bioma’s specific formulation. 
  4. Post meal discomfort:  The ingredient, Tributyrin in Bioma’s formulation may help to reduce that pesky discomfort after eating. However, keep in mind that the research is not yet in depth enough to fully support this claim.

Keep in mind, it is always best to speak with your healthcare professionals before including any new supplementation into your routine.  

Will Bioma Actually Support Weight Loss Like They Claim? 

One of Bioma main claims is that it supports weight loss. Based on the information on their ‘scientific references’ page of their website this is likely to occur through appetite regulation, reduced fat absorption and an increase in insoluable dietary fiibre. 

The supplement includes ingredients such as XOS, ‘thermogenic probiotics’ and the postbiotic tributyrin. Bioma’s claim is that this combination will support you in your weight loss. 

However, it’s important to note that the scientific articles referenced by Bioma may not directly correlate with the specific strains of probiotics in their formulation. While scientific research may support some strains of probiotics having the above mentioned effects it is unclear whether any of the strains included in this formulation actually have this benefit. 

Much of the research that has been cited on their ‘scientific references’ page of their website is non-specific or generalised research around this potential benefit. For instance, their website discusses how some probiotics may reduce fat absorption. However, when you look at the study they make reference to, it is a strain, Lactobacillus gasseri SBT2055, that may have this effect, which is not included in their formulation. 

 In terms of the types of studies, they are often small scale and not easily relatable to human outcomes. To use the above study as an example, the research on this potential fat absorption reducing strain has only been conducted in vitro, which means it hasn’t been tested outside of a petri dish. 

As with any health supplement, consulting with a healthcare professional is recommended.

Are There Any Side Effects To Using Bioma? 

Probiotics are generally considered safe for most people when used as directed, and they are commonly found in fermented foods and dietary supplements. 

However, some individuals may experience mild side effects. 

Some of the common poetntial side effects of probiotics are gas, bloating, increase in bowel movements and nausea. 

In some rare cases individuals may be allergic to particular ingredients of bacteria strains, leading to an allergic reaction. If this is something you suspect, seek medical advice. 

Some people who have weakened immune systems or are on immunosuppressive drugs should speak with their healthcare professionals before including any new supplement in their routine. 

For most people, probiotics are considered generally safe. 

How to Use Bioma?

According to the brand’s website they recommend 2 capsules before your first meal of the day. 

Where to Buy Bioma?

Bioma can be purchased through the Bioma website or through Amazon.  

How Much is Bioma?

On the brand’s website you have to go through the online ‘gut type’ quiz in order to purchase. This allows them to collect information on the common gut issues and demographic data of their customers. Before you can access their purchase page you have to answer 17 questions and input your email address. Once you have completed these requirements they provide you with some information about gut health and supporting habits. 

The purchase page lists the cost of a one month supply or one bottle as $79.99. 

On Amazon, there is no need to go through the quiz in order to purchase and the cost per bottle $57.49. 

What is Bioma’s Return Policy?

According to their website ‘Bioma offers a 14-day money back policy. This means you can return your Bioma within 14 days of receiving your purchase according to our terms & conditions’. However, their terms and conditions specify that the product can only be returned if it is unopened, faulty or the product is not as described.

Bioma Reviews

In our opinion, Amazon provides a more reliable source for genuine customer reviews compared to a brand’s official website.

According to the Amazon review summary; ‘Customers are not impressed with the performance, value, and effect of the nutritional supplement.’ Many customers mention that it does not work as advertised and that it is overrated and not worth the cost.

The Amazon review also mentions that customers have had reported side effects such as ‘severe abdominal pain and cramps.’ Customers have different opinions on weight loss, and side effects.

On Amazon.com, Bioma has earned an average rating of 3.6 out of 5 stars after more than 336 customer reviews. 

There are many 5-star reviews from customers. 

For example, one 5-star Amazon review says, ‘Good probiotics, not sure about weight loss.’ 

A four star review discusses a historical price increase and attributes their weightloss to cutting out alcohol, not the probiotic.  ’

A customer who wrote a three star review for Bioma’s product said they had not seen any weight loss but may have seen an ‘improvement in my bathroom habits and overall digestive system.’

When we look at some more low scoring reviews such as one or two star reviews the sentiment seems to be that the product is expensive, ineffective and often gave customers unwanted side effects. With one customer describing the product as a waste of their money. 

Our Verdict: Is Bioma Worth It?

While there may be benefits to the ingredients in the Bioma Probiotics blend, it is unclear as to whether their proprietary blend is supported by science. The product does seem to have fairly mixed responses on Amazon reviews. As far as probiotics go, it is on the higher cost end of the markets. Overall, we don’t think Bioma is worth the high cost and the research to support its use is unclear. 

Pros

  • Lovely branding and logos that make the product appealing. 
  • References scientific research and clinical trials, contributing to credibility and a science-backed approach. Note: unclear as to whether research has been undertaken to validate the product’s purported benefits. 
  • Inclusion of tributyrin as a postbiotic offers potential additional benefits.
  • Offers a quiz on the website for personalized insights into gut health.

Cons

  • Provides a single product without customization based on individual needs.
  • Some cited studies may not directly correlate with the specific strains in the formulation.
  • Not everyone may experience the same level of benefits.
  • Some users have described side effects with its use.
  • Lack of details on the specific Colony Forming Units (CFU) count for each strain, crucial for assessing potency and efficacy. CFU overall are low
  • Expensive 
  • Low bacterial strain variety- only three strains present 

What Are Some Alternatives to Bioma? 

Ritual Synbiotic+ Probiotic Capsules is considered all rounder for gut health with a larger variety of probiotic strains and a larger CFU count. 

Culturelle Women’s 4-in-1 Protection has a large number of lactobacillus strains which are generally more well-researched. 

Seed DS-01 Daily Synbiotic is one of the highest strengths in terms of CFU and probiotic variety. They also offer refills to their product to reduce waste. You can read our review here.

References:
Pratt, Charlotte; Campbell, Matthew D. (2019-11-18). “The Effect of Bifidobacterium on Reducing Symptomatic Abdominal Pain in Patients with Irritable Bowel Syndrome: A Systematic Review”. Probiotics and Antimicrobial Proteins. 12 (3): 834–839. doi:10.1007/s12602-019-09609-
Lim S, Moon JH, Shin CM, Jeong D, Kim B. Effect of Lactobacillus sakei, a Probiotic Derived from Kimchi, on Body Fat in Koreans with Obesity: A Randomized Controlled Study. Endocrinol Metab (Seoul). 2020 Jun;35(2):425-434. doi: 10.3803/EnM.2020.35.2.425.
Yang N, Lan T, Han Y, Zhao H, Wang C, Xu Z, Chen Z, Tao M, Li H, Song Y, Ma X. Tributyrin alleviates gut microbiota dysbiosis to repair intestinal damage in antibiotic-treated mice. PLoS One. 2023 Jul 31;18(7):e0289364. doi: 10.1371/journal.pone.0289364
Álvarez-Arraño V, Martín-Peláez S. Effects of Probiotics and Synbiotics on Weight Loss in Subjects with Overweight or Obesity: A Systematic Review. Nutrients. 2021 Oct 17;13(10):3627. doi: 10.3390/nu13103627.
Tateyama I, Hashii K, Johno I, Iino T, Hirai K, Suwa Y, Kiso Y. Effect of xylooligosaccharide intake on severe constipation in pregnant women. J Nutr Sci Vitaminol (Tokyo). 2005 Dec;51(6):445-8. doi: 10.3177/jnsv.51.445.
Cristofori F, Dargenio VN, Dargenio C, Miniello VL, Barone M, Francavilla R. Anti-Inflammatory and Immunomodulatory Effects of Probiotics in Gut Inflammation: A Door to the Body. Front Immunol. 2021 Feb 26;12:578386. doi: 10.3389/fimmu.2021.578386.
Yan F, Tian S, Du K, Xue X, Gao P, Chen Z. Preparation and nutritional properties of xylooligosaccharide from agricultural and forestry byproducts: A comprehensive review. Front Nutr. 2022 Sep 13;9:977548. doi: 10.3389/fnut.2022.977548.
Jungersen M, Wind A, Johansen E, Christensen JE, Stuer-Lauridsen B, Eskesen D. The Science behind the Probiotic Strain Bifidobacterium animalis subsp. lactis BB-12(®). Microorganisms. 2014 Mar 28;2(2):92-110. doi: 10.3390/microorganisms2020092
Ogawa A, Kobayashi T, Sakai F, Kadooka Y, Kawasaki Y. Lactobacillus gasseri SBT2055 suppresses fatty acid release through enlargement of fat emulsion size in vitro and promotes fecal fat excretion in healthy Japanese subjects. Lipids Health Dis. 2015 Mar 20;14:20. doi: 10.1186/s12944-015-0019-0. PMID: 25884980;

OUR TOP SKINCARE PICKS

1

Carrot & Stick

Carrot & Stick takes a tough love approach to skincare. What does this mean? It perfectly balances the power of plants with innovative science, offering the best of both worlds. Read More
2

Formulyst

The philosophy of Formulyst is long-term and effective skincare, rather than covering up any imperfections. The comprehensive line of products tackles everything from wrinkles to dark spots and dry skin. While some brands rely on unnecessary fillers and scents, Formulyst focuses on ingredients that help create results, such as vitamins, minerals and antioxidants. Read More

No comments yet

Your Review
User Rating: 0.0 (0 votes)
Sending

Recommended Articles